Anti-norovirus therapeutics: a patent review (2010-2015)

Biochemical Evaluation of the Inhibition Properties of Favipiravir and 2′-C-Methyl-Cytidine Triphosphates against Human and Mouse Norovirus RNA Polymerases

(2015) Zhinan Jin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Norovirus

(2015) Elizabeth Robilotti et al.   CLINICAL MICROBIOLOGY REVIEWS

Noroviruses: epidemiology, immunity and prospects for prevention

(2015) Kimberly Pringle et al.   Future Microbiology

Structure-Guided Design and Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. Structure–Activity Relationships and Biochemical, X-ray Crystallographic, Cell-Based, and In Vivo Studies

(2015) Anushka C. Galasiti Kankanamalage et al.   JOURNAL OF MEDICINAL CHEMISTRY

Molecular Chaperone Hsp90 Is a Therapeutic Target for Noroviruses

(2015) Surender Vashist et al.   JOURNAL OF VIROLOGY

Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance

(2015) Auda Eltahla et al.   Viruses-Basel

A Working Model of How Noroviruses Infect the Intestine

(2015) Stephanie M. Karst et al.   PLoS Pathogens

Nonnucleoside Inhibitors of Norovirus RNA Polymerase: Scaffolds for Rational Drug Design

(2014) Auda A. Eltahla et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Enterovirus Protease Inhibitor Rupintrivir Exerts Cross-Genotypic Anti-Norovirus Activity and Clears Cells from the Norovirus Replicon

(2014) J. Rocha-Pereira et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nitazoxanide: A first-in-class broad-spectrum antiviral agent

(2014) Jean-François Rossignol   ANTIVIRAL RESEARCH

Treatment of norovirus infections: Moving antivirals from the bench to the bedside

(2014) Stuart S. Kaufman et al.   ANTIVIRAL RESEARCH

Norovirus: Targets and tools in antiviral drug discovery

(2014) Joana Rocha-Pereira et al.   BIOCHEMICAL PHARMACOLOGY

Advances in Norovirus Biology

(2014) Stephanie M. Karst et al.   Cell Host & Microbe

Synthesis of Nucleoside Phosphate and Phosphonate Prodrugs

(2014) Ugo Pradere et al.   CHEMICAL REVIEWS

The burden of norovirus gastroenteritis: an important foodborne and healthcare-related infection

(2014) G. Belliot et al.   CLINICAL MICROBIOLOGY AND INFECTION

Evolution of norovirus

(2014) P.A. White   CLINICAL MICROBIOLOGY AND INFECTION

Affinities of human histo-blood group antigens for norovirus capsid protein complexes

(2014) Ling Han et al.   GLYCOBIOLOGY

Prophylactic treatment with the nucleoside analogue 2'-C-methylcytidine completely prevents transmission of norovirus

(2014) J. Rocha-Pereira et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The molecular pathology of noroviruses

(2014) Stephanie M Karst et al.   JOURNAL OF PATHOLOGY

Gangliosides are Ligands for Human Noroviruses

(2014) Ling Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Analysis of Determinants of Histo-Blood Group Antigen Binding Specificity in Genogroup I Noroviruses

(2014) S. Shanker et al.   JOURNAL OF VIROLOGY

Structural Bases of Norovirus RNA Dependent RNA Polymerase Inhibition by Novel Suramin-Related Compounds

(2014) Romina Croci et al.   PLoS One

Chemical Derivatives of a Small Molecule Deubiquitinase Inhibitor Have Antiviral Activity against Several RNA Viruses

(2014) Marta J. Gonzalez-Hernandez et al.   PLoS One

Enteric bacteria promote human and mouse norovirus infection of B cells

(2014) M. K. Jones et al.   SCIENCE

Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics

(2013) Sivakoteswara Rao Mandadapu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus

(2013) Sivakoteswara Rao Mandadapu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors

(2013) Allan M. Prior et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New strains of norovirus and the mystery of viral gastroenteritis epidemics

(2013) B. E. Lee et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Progress towards the prevention and treatment of norovirus infections

(2013) Armando Arias et al.   Future Microbiology

Norovirus gene expression and replication

(2013) L. G. Thorne et al.   JOURNAL OF GENERAL VIROLOGY

Identifying Carbohydrate Ligands of a Norovirus P Particle using a Catch and Release Electrospray Ionization Mass Spectrometry Assay

(2013) Ling Han et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The Viral Polymerase Inhibitor 2'-C-Methylcytidine Inhibits Norwalk Virus Replication and Protects against Norovirus-Induced Diarrhea and Mortality in a Mouse Model

(2013) J. Rocha-Pereira et al.   JOURNAL OF VIROLOGY

Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

(2013) Z. Muhaxhiri et al.   JOURNAL OF VIROLOGY

Inhibition of Histo-blood Group Antigen Binding as a Novel Strategy to Block Norovirus Infections

(2013) Xu-Fu Zhang et al.   PLoS One

Structural and dynamics characterization of norovirus protease

(2013) Daisuke Takahashi et al.   PROTEIN SCIENCE

Synthesis, activity and structure–activity relationship of noroviral protease inhibitors

(2013) Lisheng Deng et al.   MedChemComm

A Mouse Model for Human Norovirus

(2013) S. Taube et al.   mBio

Antiviral activity of nucleoside analogues against norovirus

(2012) Verónica P Costantini et al.   ANTIVIRAL THERAPY

Favipiravir (T-705) inhibits in vitro norovirus replication

(2012) J. Rocha-Pereira et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Potent norovirus inhibitors based on the acyclic sulfamide scaffold

(2012) Dengfeng Dou et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and anti-norovirus activity of pyranobenzopyrone compounds

(2012) Laxman Pokhrel et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles

(2012) Sivakoteswara Rao Mandadapu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of norovirus 3CL protease by bisulfite adducts of transition state inhibitors

(2012) Sivakoteswara Rao Mandadapu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases

(2012) Eloise Mastrangelo et al.   JOURNAL OF MOLECULAR BIOLOGY

Broad-Spectrum Antivirals against 3C or 3C-Like Proteases of Picornaviruses, Noroviruses, and Coronaviruses

(2012) Y. Kim et al.   JOURNAL OF VIROLOGY

Multiple Antigenic Sites Are Involved in Blocking the Interaction of GII.4 Norovirus Capsid with ABH Histo-Blood Group Antigens

(2012) G. I. Parra et al.   JOURNAL OF VIROLOGY

Norovirus Gastroenteritis in Immunocompromised Patients

(2012) Karin Bok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin

(2012) Intekhab Alam et al.   VIROLOGY

Applications of a Catch and Release Electrospray Ionization Mass Spectrometry Assay for Carbohydrate Library Screening

(2011) Amr El-Hawiet et al.   ANALYTICAL CHEMISTRY

Potent inhibition of Norwalk virus by cyclic sulfamide derivatives

(2011) Dengfeng Dou et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antifungal activity of a series of 1,2-benzisothiazol-3(2H)-one derivatives

(2011) Dengfeng Dou et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, and evaluation of inhibitors of Norwalk virus 3C protease

(2011) Kok-Chuan Tiew et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of noroviruses by piperazine derivatives

(2011) Dengfeng Dou et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cyclosulfamide-based derivatives as inhibitors of noroviruses

(2011) Dengfeng Dou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase

(2011) J.-H. Lee et al.   JOURNAL OF GENERAL VIROLOGY

Norovirus gastroenteritis successfully treated with nitazoxanide

(2011) Danish M. Siddiq et al.   JOURNAL OF INFECTION

Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase

(2011) Michael J. Sofia et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability

(2011) G. S. Hansman et al.   JOURNAL OF VIROLOGY

Characterization and inhibition of norovirus proteases of genogroups I and II using a fluorescence resonance energy transfer assay

(2011) Kyeong-Ok Chang et al.   VIROLOGY

Crystallography of a Lewis-Binding Norovirus, Elucidation of Strain-Specificity to the Polymorphic Human Histo-Blood Group Antigens

(2011) Yutao Chen et al.   PLoS Pathogens

A Structural Study of Norovirus 3C Protease Specificity: Binding of a Designed Active Site-Directed Peptide Inhibitor

(2010) Robert J. Hussey et al.   BIOCHEMISTRY

(E)-2-Styrylchromones as potential anti-norovirus agents

(2010) Joana Rocha-Pereira et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chimpanzees as an animal model for human norovirus infection and vaccine development

(2010) K. Bok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Norovirus Gastroenteritis, Carbohydrate Receptors, and Animal Models

(2010) Ming Tan et al.   PLoS Pathogens

Role of Cholesterol Pathways in Norovirus Replication

(2009) K.-O. Chang   JOURNAL OF VIROLOGY

Conservation of Carbohydrate Binding Interfaces — Evidence of Human HBGA Selection in Norovirus Evolution

(2009) Ming Tan et al.   PLoS One

Leader of the Capsid Protein in Feline Calicivirus Promotes Replication of Norwalk Virus in Cell Culture

(2008) K.-O. Chang et al.   JOURNAL OF VIROLOGY

Structural Basis for the Receptor Binding Specificity of Norwalk Virus

(2008) W. Bu et al.   JOURNAL OF VIROLOGY

Atomic resolution structural characterization of recognition of histo-blood group antigens by Norwalk virus

(2008) J.-M. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA