期刊
BIOORGANIC & MEDICINAL CHEMISTRY
卷 19, 期 19, 页码 5782-5787出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2011.08.029
关键词
Antifungal agents; Broad spectrum
A series of broad-spectrum antifungal agents based on the 1,2-benzisothiazol-3(2H)-one scaffold is reported. Preliminary structure-activity relationship studies have established the importance of the presence of the heterocyclic ring, a methyl group, and a phenyl ring for optimal manifestation of antifungal activity. (C) 2011 Elsevier Ltd. All rights reserved.
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