A review of emerging IL-17 inhibitors in the treatment of psoriasis focusing on preclinical through phase II studies
出版年份 2016 全文链接
标题
A review of emerging IL-17 inhibitors in the treatment of psoriasis focusing on preclinical through phase II studies
作者
关键词
-
出版物
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Volume 25, Issue 11, Pages 1337-1344
出版商
Informa UK Limited
发表日期
2016-09-30
DOI
10.1080/13543784.2016.1237502
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Development of a Topical Treatment for Psoriasis Targeting RORγ: From Bench to Skin
- (2016) Susan H. Smith et al. PLoS One
- An inflammatory triangle in psoriasis: TNF, type I IFNs and IL-17
- (2015) Lynda Grine et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Genetics of Psoriasis
- (2015) Satveer K. Mahil et al. DERMATOLOGIC CLINICS
- Protective effect of a germline, IL-17-neutralizing antibody in murine models of autoimmune inflammatory disease
- (2015) Kiran Dallenbach et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- In vivoregulation of gene expression and T helper type 17 differentiation by RORγt inverse agonists
- (2015) Jill Skepner et al. IMMUNOLOGY
- Human mast cells are major IL-22 producers in patients with psoriasis and atopic dermatitis
- (2015) Shunya Mashiko et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Interleukin-17 and innate immunity in infections and chronic inflammation
- (2015) Natasa Isailovic et al. JOURNAL OF AUTOIMMUNITY
- Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials
- (2015) Christopher E M Griffiths et al. LANCET
- Discovery and characterization of COVA322, a clinical-stage bispecific TNF/IL-17A inhibitor for the treatment of inflammatory diseases
- (2015) Michela Silacci et al. mAbs
- IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases
- (2015) Michele W L Teng et al. NATURE MEDICINE
- Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis
- (2015) Mark Lebwohl et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ursolic acid ameliorates autoimmune arthritis via suppression of Th17 and B cell differentiation
- (2014) Seung-ye Baek et al. ACTA PHARMACOLOGICA SINICA
- Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms
- (2014) Sheng Xiao et al. IMMUNITY
- The role of IL-17 in psoriasis
- (2014) Mona Malakouti et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- Total skin clearance results in improvements in health-related quality of life and reduced symptom severity among patients with moderate to severe psoriasis
- (2014) Hema N. Viswanathan et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- Pharmacologic Inhibition of ROR t Regulates Th17 Signature Gene Expression and Suppresses Cutaneous Inflammation In Vivo
- (2014) J. Skepner et al. JOURNAL OF IMMUNOLOGY
- Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials
- (2014) Richard G. Langley et al. NEW ENGLAND JOURNAL OF MEDICINE
- IL-17 Induces an Expanded Range of Downstream Genes in Reconstituted Human Epidermis Model
- (2014) Andrea Chiricozzi et al. PLoS One
- Characterization of Innate Lymphoid Cells in Human Skin and Blood Demonstrates Increase of NKp44+ ILC3 in Psoriasis
- (2013) Federica Villanova et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses
- (2013) Michelle A. Lowes et al. TRENDS IN IMMUNOLOGY
- Psoriasis: Evolving treatment for a complex disease
- (2012) J. VILLASENOR-PARK et al. CLEVELAND CLINIC JOURNAL OF MEDICINE
- Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice
- (2012) Stanislav Pantelyushin et al. JOURNAL OF CLINICAL INVESTIGATION
- Ursolic Acid Suppresses Interleukin-17 (IL-17) Production by Selectively Antagonizing the Function of RORγt Protein
- (2011) Tao Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mast Cells and Neutrophils Release IL-17 through Extracellular Trap Formation in Psoriasis
- (2011) A. M. Lin et al. JOURNAL OF IMMUNOLOGY
- Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
- (2011) Jun R. Huh et al. NATURE
- Signal transduction pathways and transcriptional regulation in Th17 cell differentiation
- (2010) Kiyoshi Hirahara et al. CYTOKINE & GROWTH FACTOR REVIEWS
- IL-23-Mediated Psoriasis-Like Epidermal Hyperplasia Is Dependent on IL-17A
- (2010) H. L. Rizzo et al. JOURNAL OF IMMUNOLOGY
- Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis
- (2010) Andrea Chiricozzi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Psoriasis
- (2009) Frank O. Nestle et al. NEW ENGLAND JOURNAL OF MEDICINE
- Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22
- (2008) Hiroaki Takatori et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
- (2008) Elisabetta Volpe et al. NATURE IMMUNOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started