Catalytic Kinetics Considerations and Molecular Tools for the Design of Multienzymatic Cascade Nanoreactors

The pharmacology of plant virus nanoparticles

(2021) Christian Isalomboto Nkanga et al.   VIROLOGY

Bi-enzymatic virus-like bionanoreactors for the transformation of endocrine disruptor compounds

(2020) Oscar González-Davis et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Quantum Dots and Gold Nanoparticles as Scaffolds for Enzymatic Enhancement: Recent Advances and the Influence of Nanoparticle Size

(2020) Gregory A. Ellis et al.   Catalysts

Plasmid Display for Stabilization of Enzymes Inside the Cell to Improve Whole-Cell Biotransformation Efficiency

(2020) Yunjeong Park et al.   Frontiers in Bioengineering and Biotechnology

Surface Display of Complex Enzymes by in Situ SpyCatcher‐SpyTag Interaction

(2020) Sabrina Gallus et al.   CHEMBIOCHEM

Multi-Enzyme Assembly on T4 Phage Scaffold

(2020) Jinny L. Liu et al.   Frontiers in Bioengineering and Biotechnology

Immobilization of Multi-Enzymes on Support Materials for Efficient Biocatalysis

(2020) Kongliang Xu et al.   Frontiers in Bioengineering and Biotechnology

Gold Nanoparticle Templating Increases the Catalytic Rate of an Amylase, Maltase, and Glucokinase Multienzyme Cascade through Substrate Channeling Independent of Surface Curvature

(2020) Sebastián A. Díaz et al.   ACS Catalysis

Synthetic Virus-like Particles for Glutathione Biosynthesis

(2020) Yang Wang et al.   ACS Synthetic Biology

Surface display of organophosphorus-degrading enzymes on the recombinant spore of Bacillus subtilis

(2019) Tianyu Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy

(2019) Qing Wu et al.   Nature Communications

Creation of a functional hyperthermostable designer cellulosome

(2019) Amaranta Kahn et al.   Biotechnology for Biofuels

Multienzymatic Cascade Reactions via Enzyme Complex by Immobilization

(2019) Ee Taek Hwang et al.   ACS Catalysis

Bacillus subtilis Spore Surface Display of Haloalkane Dehalogenase DhaA

(2019) Fuli Wang et al.   CURRENT MICROBIOLOGY

Production of trehalose with trehalose synthase expressed and displayed on the surface of Bacillus subtilis spores

(2019) Hongling Liu et al.   Microbial Cell Factories

Enzyme immobilization in cage-like 3D-network PVA-H and GO modified PVA-H (GO@PVA-H) with stable conformation and high activity

(2019) Qinxue Yang et al.   CHEMICAL ENGINEERING JOURNAL

Application of Immobilized Enzymes in Food Industry

(2019) Ekaterina D. Yushkova et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Multienzymatic Nanoassemblies: Recent Progress and Applications

(2019) Archontoula Giannakopoulou et al.   TRENDS IN BIOTECHNOLOGY

Recent progress in multienzymes co-immobilization and multienzyme system applications

(2019) Sizhu Ren et al.   CHEMICAL ENGINEERING JOURNAL

Surface Display of Antigen Protein VP8* of Porcine Rotavirus on Bacillus Subtilis Spores Using CotB as a Fusion Partner

(2019) Wanqiang Li et al.   MOLECULES

Study of molecular transport through a single nanopore in the membrane of a giant unilamellar vesicle using COMSOL simulation

(2019) Mohammad Abu Sayem Karal et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Design and tailoring of an artificial DNA scaffolding system for efficient lycopene synthesis using zinc-finger-guided assembly

(2019) Xian Xu et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Approaching infinite affinity through engineering of peptide–protein interaction

(2019) Anthony H. Keeble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A DNA-scaffold platform enhances a multi-enzymatic cycling reaction

(2018) Yasumasa Mashimo et al.   BIOTECHNOLOGY LETTERS

Protein cage assembly across multiple length scales

(2018) William M. Aumiller et al.   CHEMICAL SOCIETY REVIEWS

Expanding the boundary of biocatalysis: design and optimization of in vitro tandem catalytic reactions for biochemical production

(2018) Yajie Wang et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Nanoreactors: Strategies to encapsulate enzyme biocatalysts in virus-like particles

(2018) Joshua W. Wilkerson et al.   New Biotechnology

Sporobeads: The Utilization of the Bacillus subtilis Endospore Crust as a Protein Display Platform

(2018) Julia Bartels et al.   ACS Synthetic Biology

Biomimetic Cascade Network between Interactive Multicompartments Organized by Enzyme-Loaded Silica Nanoreactors

(2018) Seong-Min Jo et al.   ACS Applied Materials & Interfaces

Enhancing Coupled Enzymatic Activity by Colocalization on Nanoparticle Surfaces: Kinetic Evidence for Directed Channeling of Intermediates

(2018) James Nicholas Vranish et al.   ACS Nano

Enzymatic Cascade Reactions in Biosynthesis

(2018) Christopher T. Walsh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multifunctional Enzyme Packaging and Catalysis in the Qβ Protein Nanoparticle

(2018) Jason D. Fiedler et al.   BIOMACROMOLECULES

Enzyme fusions in biocatalysis - Coupling reactions by pairing enzymes

(2018) Friso Aalbers et al.   CHEMBIOCHEM

A genetically-encoded synthetic self-assembled multienzyme complex of lipase and P450 fatty acid decarboxylase for efficient bioproduction of fatty alkenes

(2018) Fei Li et al.   BIORESOURCE TECHNOLOGY

Development of a novel bi-enzymatic silver dendritic hierarchical nanostructure cascade catalytic system for efficient conversion of starch into gluconic acid

(2018) Saghar Rezaei et al.   CHEMICAL ENGINEERING JOURNAL

Queueing Theory-Based Perspective of the Kinetics of “Channeled” Enzyme Cascade Reactions

(2018) Stanislav Tsitkov et al.   ACS Catalysis

Engineering bi-functional enzyme complex of formate dehydrogenase and leucine dehydrogenase by peptide linker mediated fusion for accelerating cofactor regeneration

(2017) Yonghui Zhang et al.   ENGINEERING IN LIFE SCIENCES

Assembling Enzymatic Cascade Pathways inside Virus-Based Nanocages Using Dual-Tasking Nucleic Acid Tags

(2017) Melanie Brasch et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A bienzymatic biocatalyst constituted by glucose oxidase and Horseradish peroxidase immobilized on ordered mesoporous silica

(2017) Federica Pitzalis et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Simulation of intermediate transport in nanoscale scaffolds for multistep catalytic reactions

(2017) Erica Earl et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Artificial Cell Fermentation as a Platform for Highly Efficient Cascade Conversion

(2017) Kei Fujiwara et al.   ACS Synthetic Biology

Biocatalytic virus capsid as nanovehicle for enzymatic activation of Tamoxifen in tumor cells

(2017) Alejandro Tapia-Moreno et al.   Biotechnology Journal

A parts list for fungal cellulosomes revealed by comparative genomics

(2017) Charles H. Haitjema et al.   Nature Microbiology

Mesoporous Silica Nanoparticles with Large Pores for the Encapsulation and Release of Proteins

(2016) Jing Tu et al.   ACS Applied Materials & Interfaces

Approach To Deliver Two Antioxidant Enzymes with Mesoporous Silica Nanoparticles into Cells

(2016) Yu-Hsuan Lin et al.   ACS Applied Materials & Interfaces

Insights into the functionality and stability of designer cellulosomes at elevated temperatures

(2016) Anastasia P. Galanopoulou et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A Catalytic Nanoreactor Based on in Vivo Encapsulation of Multiple Enzymes in an Engineered Protein Nanocompartment

(2016) Tobias W. Giessen et al.   CHEMBIOCHEM

Graphene-Oxide-Based Enzyme Nanoarchitectonics for Substrate Channeling

(2016) Motilal Mathesh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Carbon Nanodots as Peroxidase Nanozymes for Biosensing

(2016) Bhaskar Garg et al.   MOLECULES

Substrate channelling as an approach to cascade reactions

(2016) Ian Wheeldon et al.   Nature Chemistry

Enzymatic reactions in confined environments

(2016) Andreas Küchler et al.   Nature Nanotechnology

Immobilized multienzymatic systems for catalysis of cascade reactions

(2016) Qingzhi Ji et al.   PROCESS BIOCHEMISTRY

Coupling two enzymes into a tandem nanoreactor utilizing a hierarchically structured MOF

(2016) Xizhen Lian et al.   Chemical Science

Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade

(2016) Yifei Zhang et al.   Nature Communications

Investigation on characteristics of liquid self-diffusion in slit nanopores using simple quasicrystal model of liquid

(2015) Guangze Han et al.   CHINESE JOURNAL OF CHEMICAL ENGINEERING

Expression and display of a novel thermostable esterase from Clostridium thermocellum on the surface of Bacillus subtilis using the CotB anchor protein

(2015) Huayou Chen et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Graphene-Based Nanomaterials as Efficient Peroxidase Mimetic Catalysts for Biosensing Applications: An Overview

(2015) Bhaskar Garg et al.   MOLECULES

Bienzyme–Polymer–Graphene Oxide Quaternary Hybrid Biocatalysts: Efficient Substrate Channeling under Chemically and Thermally Denaturing Conditions

(2015) Omkar V. Zore et al.   ACS Catalysis

Tuning Enzyme Kinetics through Designed Intermolecular Interactions Far from the Active Site

(2015) Yingning Gao et al.   ACS Catalysis

Design of a VLP-nanovehicle for CYP450 enzymatic activity delivery

(2015) Lorena Sánchez-Sánchez et al.   JOURNAL OF NANOBIOTECHNOLOGY

Confined Multiple Enzymatic (Cascade) Reactions within Poly(dopamine)-based Capsosomes

(2014) Leticia Hosta-Rigau et al.   ACS Applied Materials & Interfaces

Cascade Biocatalysis by Multienzyme–Nanoparticle Assemblies

(2014) Wei Kang et al.   BIOCONJUGATE CHEMISTRY

Assembly of zinc finger motif-fused enzymes on a dsDNA scaffold for catalyzing consecutive reactions with a proximity effect

(2014) Hisakage Funabashi et al.   BIOTECHNOLOGY LETTERS

Chemotherapy pro-drug activation by biocatalytic virus-like nanoparticles containing cytochrome P450

(2014) Lorena Sánchez-Sánchez et al.   ENZYME AND MICROBIAL TECHNOLOGY

Co-immobilization of multi-enzyme on control-reduced graphene oxide by non-covalent bonds: an artificial biocatalytic system for the one-pot production of gluconic acid from starch

(2014) Fuhua Zhao et al.   GREEN CHEMISTRY

Coimmobilization of Acetylcholinesterase and Choline Oxidase on Gold Nanoparticles: Stoichiometry, Activity, and Reaction Efficiency

(2014) Jacqueline D. Keighron et al.   LANGMUIR

A system of vectors for Bacillus subtilis spore surface display

(2014) Adam Iwanicki et al.   Microbial Cell Factories

Inorganic Materials as Supports for Covalent Enzyme Immobilization: Methods and Mechanisms

(2014) Paolo Zucca et al.   MOLECULES

Graphene-based nanobiocatalytic systems: recent advances and future prospects

(2014) Ioannis V. Pavlidis et al.   TRENDS IN BIOTECHNOLOGY

Encapsulation of an Enzyme Cascade within the Bacteriophage P22 Virus-Like Particle

(2013) Dustin P. Patterson et al.   ACS Chemical Biology

Surface Display of Human Growth Hormone on Bacillus subtilis Spores for Oral Administration

(2013) Chaoqun Lian et al.   CURRENT MICROBIOLOGY

Display of Human Proinsulin on the Bacillus subtilis Spore Surface for Oral Administration

(2013) Fan Feng et al.   CURRENT MICROBIOLOGY

Chemical approaches for the construction of multi-enzyme reaction systems

(2013) Sanne Schoffelen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Current status and trends in enzymatic nanoimmobilization

(2013) Eliane P. Cipolatti et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Regulation of an Enzyme Cascade Reaction by a DNA Machine

(2013) Ling Xin et al.   Small

Kinetic Enhancements in DNA–Enzyme Nanostructures Mimic the Sabatier Principle

(2013) Jyun-Liang Lin et al.   ACS Catalysis

Fusion protein linkers: Property, design and functionality

(2012) Xiaoying Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Coconfinement of Fluorescent Proteins: Spatially Enforced Communication of GFP and mCherry Encapsulated within the P22 Capsid

(2012) Alison O’Neil et al.   BIOMACROMOLECULES

Interenzyme Substrate Diffusion for an Enzyme Cascade Organized on Spatially Addressable DNA Nanostructures

(2012) Jinglin Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Natural strategies for the spatial optimization of metabolism in synthetic biology

(2012) Christina M Agapakis et al.   Nature Chemical Biology

Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

(2012) B. Zakeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced cellulose degradation by targeted integration of a cohesin-fused  -glucosidase into the Clostridium thermocellum cellulosome

(2012) G. Gefen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-Assembly of Synthetic Metabolons through Synthetic Protein Scaffolds: One-Step Purification, Co-immobilization, and Substrate Channeling

(2012) Chun You et al.   ACS Synthetic Biology

Nanotube-supported bioproduction of 4-hydroxy-2-butanone via in situ cofactor regeneration

(2011) Liang Wang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Modeling Self-Diffusion of Simple Fluids in Nanopores

(2011) Suresh K. Bhatia et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Controlling protein translocation through nanopores with bio-inspired fluid walls

(2011) Erik C. Yusko et al.   Nature Nanotechnology

Directed Evolution of a Protein Container

(2011) B. Worsdorfer et al.   SCIENCE

Organization of Intracellular Reactions with Rationally Designed RNA Assemblies

(2011) C. J. Delebecque et al.   SCIENCE

Multi-enzyme systems: bringing enzymes together in vitro

(2011) Sanne Schoffelen et al.   Soft Matter

Effect of diffusion on enzyme activity in a microreactor

(2010) Jan W. Swarts et al.   CHEMICAL ENGINEERING JOURNAL

Immobilization of lignin peroxidase on nanoporous gold: Enzymatic properties and in situ release of H2O2 by co-immobilized glucose oxidase

(2009) Huajun Qiu et al.   BIORESOURCE TECHNOLOGY

A Three-Enzyme Cascade Reaction through Positional Assembly of Enzymes in a Polymersome Nanoreactor

(2008) Stijn F. M. van Dongen et al.   CHEMISTRY-A EUROPEAN JOURNAL