Interaction of silymarin components and their sulfate metabolites with human serum albumin and cytochrome P450 (2C9, 2C19, 2D6, and 3A4) enzymes
出版年份 2021 全文链接
标题
Interaction of silymarin components and their sulfate metabolites with human serum albumin and cytochrome P450 (2C9, 2C19, 2D6, and 3A4) enzymes
作者
关键词
Silymarin, Sulfate conjugates, Human serum albumin, Cytochrome P450, Pharmacokinetic interaction, Herb-drug interaction
出版物
BIOMEDICINE & PHARMACOTHERAPY
Volume 138, Issue -, Pages 111459
出版商
Elsevier BV
发表日期
2021-03-09
DOI
10.1016/j.biopha.2021.111459
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Silymarin as Supportive Treatment in Liver Diseases: A Narrative Review
- (2020) Anton Gillessen et al. ADVANCES IN THERAPY
- Silymarin and Cancer: A Dual Strategy in Both in Chemoprevention and Chemosensitivity
- (2020) Dominique Delmas et al. MOLECULES
- Testing the Pharmacokinetic Interactions of 24 Colonic Flavonoid Metabolites with Human Serum Albumin and Cytochrome P450 Enzymes
- (2020) Violetta Mohos et al. Biomolecules
- Effects of chrysin and its major conjugated metabolites chrysin-7-sulfate and chrysin-7-glucuronide on cytochrome P450 enzymes, and on OATP, P-gp, BCRP and MRP2 transporters
- (2020) Violetta Mohos et al. DRUG METABOLISM AND DISPOSITION
- Inhibitory Effects of Quercetin and Its Main Methyl, Sulfate, and Glucuronic Acid Conjugates on Cytochrome P450 Enzymes, and on OATP, BCRP and MRP2 Transporters
- (2020) Violetta Mohos et al. Nutrients
- Identification of Human Sulfotransferases Active towards Silymarin Flavonolignans and Taxifolin
- (2020) Jiří Vrba et al. Metabolites
- The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction
- (2020) Fengyan Xiao et al. MEDICINE
- Effects of silymarin supplementation on blood lipids: A systematic review and meta-analysis of clinical trials
- (2019) Hamed Mohammadi et al. PHYTOTHERAPY RESEARCH
- Defying Multidrug resistance! Modulation of Related Transporters by Flavonoids and Flavonolignans
- (2019) Christopher Steven Chambers et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Silymarin’s Inhibition and Treatment Effects for Alzheimer’s Disease
- (2019) Hong Guo et al. MOLECULES
- Inhibitory Effects of Quercetin and Its Human and Microbial Metabolites on Xanthine Oxidase Enzyme
- (2019) Violetta Mohos et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Silymarin antiproliferative and apoptotic effects: Insights into its clinical impact in various types of cancer
- (2019) Tahereh Hosseinabadi et al. PHYTOTHERAPY RESEARCH
- A glassy carbon electrode modified with a nanocomposite prepared from Pd/Al layered double hydroxide and carboxymethyl cellulose for voltammetric sensing of hydrogen peroxide
- (2019) Gozal Fazli et al. MICROCHIMICA ACTA
- Metabolism, Transport and Drug–Drug Interactions of Silymarin
- (2019) Xie et al. MOLECULES
- The Effect of Silymarin Flavonolignans and Their Sulfated Conjugates on Platelet Aggregation and Blood Vessels Ex Vivo
- (2019) Jana Pourová et al. Nutrients
- Interactions of 7,8-Dihydroxyflavone with Serum Albumin as well as with CYP2C9, CYP2C19, CYP3A4, and Xanthine Oxidase Biotransformation Enzymes
- (2019) Fliszár-Nyúl et al. Biomolecules
- Antioxidant, Anti-Inflammatory, and Multidrug Resistance Modulation Activity of Silychristin Derivatives
- (2019) Jitka Viktorová et al. Antioxidants
- Antioxidant effects and mechanism of silymarin in oxidative stress induced cardiovascular diseases
- (2018) Abdoh Taleb et al. BIOMEDICINE & PHARMACOTHERAPY
- Pharmacokinetic interaction of diosmetin and silibinin with other drugs: Inhibition of CYP2C9-mediated biotransformation and displacement from serum albumin
- (2018) Miklós Poór et al. BIOMEDICINE & PHARMACOTHERAPY
- Metabolism of flavonolignans in human hepatocytes
- (2018) Jiří Vrba et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Effects of silymarin on metabolic syndrome: a review
- (2018) Maryam Vahabzadeh et al. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
- Anti-Parkinson Potential of Silymarin: Mechanistic Insight and Therapeutic Standing
- (2018) Hammad Ullah et al. Frontiers in Pharmacology
- Sulfated Metabolites of Flavonolignans and 2,3-Dehydroflavonolignans: Preparation and Properties
- (2018) Kateřina Valentová et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Milk thistle (Silybum marianum ): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases
- (2018) Ludovico Abenavoli et al. PHYTOTHERAPY RESEARCH
- Interaction of Chrysin and Its Main Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide with Serum Albumin
- (2018) Violetta Mohos et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The silymarin composition… and why does it matter???
- (2017) Christopher Steven Chambers et al. FOOD RESEARCH INTERNATIONAL
- Silymarin impacts on immune system as an immunomodulator: One key for many locks
- (2017) Nafiseh Esmaeil et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years
- (2017) Alessandro Federico et al. MOLECULES
- Effects of Silymarin on Diabetes Mellitus Complications: A Review
- (2017) Aline Maria Stolf et al. PHYTOTHERAPY RESEARCH
- Effect of silymarin on biochemical indicators in patients with liver disease: Systematic review with meta-analysis
- (2017) Camila Ribeiro de Avelar et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Silymarin: a potent hepatoprotective agent in poultry industry
- (2017) M. SAEED et al. WORLDS POULTRY SCIENCE JOURNAL
- Silychristin: Skeletal Alterations and Biological Activities
- (2016) David Biedermann et al. JOURNAL OF NATURAL PRODUCTS
- Silymarin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- (2016) Luminita Voroneanu et al. Journal of Diabetes Research
- Silymarin and its constituents in cardiac preconditioning
- (2014) A. Zholobenko et al. FITOTERAPIA
- Albumin–drug interaction and its clinical implication
- (2013) Keishi Yamasaki et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Bioavailability of silymarin flavonolignans: drug formulations and biotransformation
- (2013) Eleni Theodosiou et al. PHYTOCHEMISTRY REVIEWS
- A sensitive LC–MS/MS assay for the simultaneous analysis of the major active components of silymarin in human plasma
- (2012) Bryan J. Brinda et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Preparation of silybin and isosilybin sulfates by sulfotransferase from Desulfitobacterium hafniense
- (2012) Petr Marhol et al. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
- Absorption and metabolism of milk thistle flavanolignans in humans
- (2012) Luca Calani et al. PHYTOMEDICINE
- Preparative method for isosilybin isolation based on enzymatic kinetic resolution of silymarin mixture
- (2012) Radek Gažák et al. PROCESS BIOCHEMISTRY
- Investigation on the interactions of silymarin to bovine serum albumin and lysozyme by fluorescence and absorbance
- (2011) Bo Pang et al. JOURNAL OF LUMINESCENCE
- Human serum albumin: From bench to bedside
- (2011) Gabriella Fanali et al. MOLECULAR ASPECTS OF MEDICINE
- Large-scale separation of silybin diastereoisomers using lipases
- (2010) Radek Gažák et al. PROCESS BIOCHEMISTRY
- Significance of Protein Binding in Pharmacokinetics and Pharmacodynamics
- (2009) Stephan Schmidt et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Two Flavonolignans from Milk Thistle (Silybum marianum) Inhibit CYP2C9-Mediated Warfarin Metabolism at Clinically Achievable Concentrations
- (2009) S. J. Brantley et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Multitargeted therapy of cancer by silymarin
- (2008) Kumaraguruparan Ramasamy et al. CANCER LETTERS
- The interaction of silibinin with human serum albumin: A spectroscopic investigation
- (2007) Tushar Kanti Maiti et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
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