A global integrated analysis of UNC5C down-regulation in cancers: insights from mechanism and combined treatment strategy

A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells

(2020) Lei Guo et al.   Nature Communications

AID assists DNMT1 to attenuate BCL6 expression through DNA methylation in diffuse large B-cell lymphoma cell lines

(2020) Junna Jiao et al.   NEOPLASIA

CUDC‐907, a novel dual PI3K and HDAC inhibitor, in prostate cancer: Antitumour activity and molecular mechanism of action

(2020) Cheng Hu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation

(2020) Li Ren Kong et al.   Nature Communications

TET2 suppresses nasopharyngeal carcinoma progression by inhibiting glycolysis metabolism

(2020) Xixia Zhang et al.   Cancer Cell International

Purine/purine isoster based scaffolds as new derivatives of benzamide class of HDAC inhibitors

(2020) Kunal Nepali et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice

(2020) Stephanie Perkail et al.   Nature Communications

An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

(2019) Marian L. Burr et al.   CANCER CELL

LncRNA DANCR promotes cervical cancer progression by upregulating ROCK1 via sponging miR-335-5p

(2018) Huiling Liang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The DNA methyltransferase family: a versatile toolkit for epigenetic regulation

(2017) Frank Lyko   NATURE REVIEWS GENETICS

Methylation of the UNC5C gene and its protein expression in colorectal cancer

(2017) Jie Wu et al.   TUMOR BIOLOGY

miR-93-3p inhibition suppresses clear cell renal cell carcinoma proliferation, metastasis and invasion

(2017) Lu Wang et al.   Oncotarget

The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches

(2016) Andreas C. Joerger et al.   Annual Review of Biochemistry

Epigenetic balance of gene expression by Polycomb and COMPASS families

(2016) Andrea Piunti et al.   SCIENCE

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

Structural Basis for the Discriminative Recognition ofN6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins

(2015) Chao Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions

(2015) Nian Liu et al.   NATURE

PTEN

(2014) Carolyn A. Worby et al.   Annual Review of Biochemistry

Gene expression regulation mediated through reversible m6A RNA methylation

(2014) Ye Fu et al.   NATURE REVIEWS GENETICS

TET enzymes, TDG and the dynamics of DNA demethylation

(2013) Rahul M. Kohli et al.   NATURE

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer

(2013) J Wang et al.   ONCOGENE

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Genetic and epigenetic control of UNC5C expression in human renal cell carcinoma

(2011) Dan Lv et al.   EUROPEAN JOURNAL OF CANCER

Variants in the Netrin-1 Receptor UNC5C Prevent Apoptosis and Increase Risk of Familial Colorectal Cancer

(2011) Marie–May Coissieux et al.   GASTROENTEROLOGY

The evolution of Fox genes and their role in development and disease

(2009) Sridhar Hannenhalli et al.   NATURE REVIEWS GENETICS

Aberrant Methylation of the Netrin-1 Receptor Genes UNC5C and DCC Detected in Advanced Colorectal Cancer

(2009) Kenji Hibi et al.   WORLD JOURNAL OF SURGERY