Inhibition of METTL3/m6A/miR126 promotes the migration and invasion of endometrial stromal cells in endometriosis

The m6A methyltransferase METTL3 contributes to Transforming Growth Factor-beta-induced epithelial-mesenchymal transition of lung cancer cells through the regulation of JUNB

(2020) Sasithorn Wanna-udom et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

N6-methyladenosine METTL3 modulates the proliferation and apoptosis of lens epithelial cells in diabetic cataract

(2020) Jun Yang et al.   Molecular Therapy-Nucleic Acids

MicroRNA‑16 inhibits endometrial stromal cell migration and invasion through suppression of the inhibitor of nuclear factor‑κB kinase subunit β/nuclear factor‑κB pathway

(2020) Xiaoping Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

METTL3-mediated maturation of miR-126-5p promotes ovarian cancer progression via PTEN-mediated PI3K/Akt/mTOR pathway

(2020) Xuehan Bi et al.   CANCER GENE THERAPY

LncRNA MALAT1 inhibits apoptosis of endometrial stromal cells through miR-126-5p-CREB1 axis by activating PI3K-AKT pathway

(2020) Ying Feng et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Assessing Research Gaps and Unmet Needs in Endometriosis

(2019) Sawsan As-Sanie et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Endometriosis

(2019) Serdar E Bulun et al.   ENDOCRINE REVIEWS

The role of m6A RNA methylation in human cancer

(2019) Xiao-Yu Chen et al.   Molecular Cancer

Dysregulated N6-methyladenosine methylation writer METTL3 contributes to the proliferation and migration of gastric cancer

(2019) Tong Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner

(2019) Jie Han et al.   Molecular Cancer

m6A methyltransferase METTL3 suppresses colorectal cancer proliferation and migration through p38/ERK pathways

(2019) Ru Deng et al.   OncoTargets and Therapy

Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway

(2019) Wen Peng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MicroRNA-126-5p downregulates BCAR3 expression to promote cell migration and invasion in endometriosis

(2019) Xiannan Meng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Rethinking mechanisms, diagnosis and management of endometriosis

(2019) Charles Chapron et al.   Nature Reviews Endocrinology

METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer

(2019) Ben Yue et al.   Molecular Cancer

HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g

(2018) Xiaoli Cai et al.   CANCER LETTERS

Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d

(2018) Philip Knuckles et al.   GENES & DEVELOPMENT

RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2

(2018) Mengnuo Chen et al.   HEPATOLOGY

Multiple functions of m6A RNA methylation in cancer

(2018) Yutian Pan et al.   Journal of Hematology & Oncology

N 6-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential

(2018) Dandan Yang et al.   NUCLEIC ACIDS RESEARCH

Estradiol promotes EMT in endometriosis via MALAT1/miR200s sponge function

(2018) Yu Du et al.   REPRODUCTION

mir-126 rs4636297 and TGFβRI rs334348 functional gene variants are associated with susceptibility to endometriosis and its severity

(2017) Neda Sepahi et al.   GYNECOLOGICAL ENDOCRINOLOGY

m 6 A Facilitates eIF4F-Independent mRNA Translation

(2017) Ryan A. Coots et al.   MOLECULAR CELL

Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control

(2017) Isaia Barbieri et al.   NATURE

Human m6A writers: Two subunits, 2 roles

(2017) Xiang Wang et al.   RNA Biology

ALKBHs-facilitated RNA modifications and de-modifications

(2016) Endalkachew A. Alemu et al.   DNA REPAIR

Aromatase inhibitor regulates let-7 expression and let-7f–induced cell migration in endometrial cells from women with endometriosis

(2016) SiHyun Cho et al.   FERTILITY AND STERILITY

METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulatingN6-methyladenosine-dependent primary MicroRNA processing

(2016) Jin-zhao Ma et al.   HEPATOLOGY

Hypoxia-inducible factor 1α-induced epithelial–mesenchymal transition of endometrial epithelial cells may contribute to the development of endometriosis

(2016) Yao Xiong et al.   HUMAN REPRODUCTION

Sexual function in endometriosis patients and their partners: effect of the disease and consequences of treatment

(2016) Nicola Pluchino et al.   HUMAN REPRODUCTION UPDATE

Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

(2016) Ping Wang et al.   MOLECULAR CELL

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

(2016) Xiang Wang et al.   NATURE

Reversible methylation of m6Am in the 5′ cap controls mRNA stability

(2016) Jan Mauer et al.   NATURE

YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

(2016) Hao Du et al.   Nature Communications

Structural insights into the molecular mechanism of the m6A writer complex

(2016) Paweł Śledź et al.   eLife

The Role of the Lymphatic System in Endometriosis: A Comprehensive Review of the Literature1

(2015) Laila F. Jerman et al.   BIOLOGY OF REPRODUCTION

HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events

(2015) Claudio R. Alarcón et al.   CELL

N6-methyladenosine marks primary microRNAs for processing

(2015) Claudio R. Alarcón et al.   NATURE

The Role of Stem Cells in the Etiology and Pathophysiology of Endometriosis

(2015) Demetra Hufnagel et al.   SEMINARS IN REPRODUCTIVE MEDICINE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Endometriosis: pathogenesis and treatment

(2013) Paolo Vercellini et al.   Nature Reviews Endocrinology

Müllerianosis

(2013) Ronald E. Batt et al.   Reproductive Sciences

The burden of endometriosis: costs and quality of life of women with endometriosis and treated in referral centres

(2012) S. Simoens et al.   HUMAN REPRODUCTION

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Leptin receptor is induced in endometriosis and leptin stimulates the growth of endometriotic epithelial cells through the JAK2/STAT3 and ERK pathways

(2012) H. K. Oh et al.   MOLECULAR HUMAN REPRODUCTION

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Expression of miR-126 and Crk in endometriosis: miR-126 may affect the progression of endometriosis by regulating Crk expression

(2011) Shuang Liu et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries

(2011) Kelechi E. Nnoaham et al.   FERTILITY AND STERILITY

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

A Non-Heme Iron-Mediated Chemical Demethylation in DNA and RNA

(2009) Chengqi Yi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Endometriosis

(2009) Serdar E. Bulun   NEW ENGLAND JOURNAL OF MEDICINE

Modeling the early endometriotic lesion: mesothelium-endometrial cell co-culture increases endometrial invasion and alters mesothelial and endometrial gene transcription

(2008) Anitha S. Nair et al.   FERTILITY AND STERILITY