Targeting of NADPH oxidase in vitro and in vivo suppresses fibroblast activation and experimental skin fibrosis

Increased Expression of NAPDH Oxidase 4 in Systemic Sclerosis Dermal Fibroblasts: Regulation by Transforming Growth Factor β

(2015) Sonsoles Piera-Velazquez et al.   Arthritis & Rheumatology

A Reactive Oxygen Species-Mediated Loop Maintains Increased Expression of NADPH Oxidases 2 and 4 in Skin Fibroblasts From Patients With Systemic Sclerosis

(2015) Tatiana Spadoni et al.   Arthritis & Rheumatology

Is Nox4 a key regulator of the activated state of fibroblasts in systemic sclerosis?

(2014) Markus Böhm et al.   EXPERIMENTAL DERMATOLOGY

Fibroblast-to-myofibroblast switch is mediated by NAD(P)H oxidase generated reactive oxygen species

(2013) Lirija Alili et al.   BIOSCIENCE REPORTS

Activation of NADPH Oxidase 4 in the Endoplasmic Reticulum Promotes Cardiomyocyte Autophagy and Survival During Energy Stress Through the Protein Kinase RNA-Activated-Like Endoplasmic Reticulum Kinase/Eukaryotic Initiation Factor 2α/Activating Transcription Factor 4 Pathway

(2013) Sebastiano Sciarretta et al.   CIRCULATION RESEARCH

Inhibition of sumoylation prevents experimental fibrosis

(2012) Aisa Khodzhigorova et al.   ANNALS OF THE RHEUMATIC DISEASES

Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model

(2012) Agatha Stegemann et al.   ARTHRITIS AND RHEUMATISM

The NOX toolbox: validating the role of NADPH oxidases in physiology and disease

(2012) Sebastian Altenhöfer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

(2012) Katrin Schröder et al.   CIRCULATION RESEARCH

Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent

(2012) Tomonori Aoyama et al.   HEPATOLOGY

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

(2011) Balaraman Kalyanaraman et al.   FREE RADICAL BIOLOGY AND MEDICINE

The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4

(2011) Ina Takac et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH Oxidase-Mediated Redox Signaling: Roles in Cellular Stress Response, Stress Tolerance, and Tissue Repair

(2011) F. Jiang et al.   PHARMACOLOGICAL REVIEWS

NADPH oxidase 4 is an oncoprotein localized to mitochondria

(2010) Kelly A. Graham et al.   CANCER BIOLOGY & THERAPY

Nox4 B-loop Creates an Interface between the Transmembrane and Dehydrogenase Domains

(2010) Heather M. Jackson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NAD(P)H Oxidase Mediates TGF- 1-Induced Activation of Kidney Myofibroblasts

(2009) C. D. Bondi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE