标题
Latest update on chemokine receptors as therapeutic targets
作者
关键词
-
出版物
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 49, Issue 3, Pages 1385-1395
出版商
Portland Press Ltd.
发表日期
2021-06-02
DOI
10.1042/bst20201114
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- The G Protein-Coupled Receptor Kinases (GRKs) in Chemokine Receptor-Mediated Immune Cell Migration: From Molecular Cues to Physiopathology
- (2021) Marta Laganà et al. Cells
- Co-targeting of CXCR4 and hedgehog pathways disrupts tumor-stromal crosstalk and improves chemotherapeutic efficacy in pancreatic cancer
- (2020) Mohammad Aslam Khan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CXCL12/CXCR4 axis in the microenvironment of solid tumors: A critical mediator of metastasis
- (2020) Keywan Mortezaee LIFE SCIENCES
- CCR7 as a therapeutic target in Cancer
- (2020) Anwar Salem et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- G Protein‐Coupled receptors and heterotrimeric G proteins as cancer drivers
- (2020) Nadia Arang et al. FEBS LETTERS
- Discovery of the Potent, Selective, Orally Available CXCR7 Antagonist ACT-1004-1239
- (2020) Sylvia Richard-Bildstein et al. JOURNAL OF MEDICINAL CHEMISTRY
- CXCR7: a β-arrestin-biased receptor that potentiates cell migration and recruits β-arrestin2 exclusively through Gβγ subunits and GRK2
- (2020) Huong Thi Nguyen et al. Cell and Bioscience
- New Routes in GPCR/β-Arrestin-Driven Signaling in Cancer Progression and Metastasis
- (2019) Anna Bagnato et al. Frontiers in Pharmacology
- Mogamulizumab: a new tool for management of cutaneous T-cell lymphoma
- (2019) Thomas A Ollila et al. OncoTargets and Therapy
- Advancing Chemokine GPCR Structure Based Drug Discovery
- (2019) Suwen Zhao et al. STRUCTURE
- CXCR4/ACKR3 phosphorylation and recruitment of interacting proteins: key mechanisms regulating their functional status
- (2019) Amos Fumagalli et al. MOLECULAR PHARMACOLOGY
- Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy
- (2019) Victoria Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chemokine receptor crystal structures: what can be learnt from them?
- (2019) Marta Arimont et al. MOLECULAR PHARMACOLOGY
- Leukocyte Adhesion: Reconceptualizing Chemokine Presentation by Glycosaminoglycans
- (2019) Gerard J. Graham et al. TRENDS IN IMMUNOLOGY
- The Role of the CXCL12/CXCR4/ACKR3 Axis in Autoimmune Diseases
- (2019) Eva M. García-Cuesta et al. Frontiers in Endocrinology
- CXCL12-CXCL4 heterodimerization prevents CXCL12-driven breast cancer cell migration
- (2019) Khanh T.P. Nguyen et al. CELLULAR SIGNALLING
- Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3
- (2018) Martyna Szpakowska et al. BRITISH JOURNAL OF PHARMACOLOGY
- A guide to chemokines and their receptors
- (2018) Catherine E. Hughes et al. FEBS Journal
- Structure and dynamics of GPCR signaling complexes
- (2018) Daniel Hilger et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure and dynamics of GPCR signaling complexes
- (2018) Daniel Hilger et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Closely related, yet unique: Distinct homo- and heterodimerization patterns of G protein coupled chemokine receptors and their fine-tuning by cholesterol
- (2018) Stefan Gahbauer et al. PLoS Computational Biology
- Pathological roles of the homeostatic chemokine CXCL12
- (2018) Rik Janssens et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Regulation of Chemokine Function: The Roles of GAG-Binding and Post-Translational Nitration
- (2017) Sarah Thompson et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Modulation of Chemokine Receptor Function by Cholesterol: New Prospects for Pharmacological Intervention
- (2017) Daniel F. Legler et al. MOLECULAR PHARMACOLOGY
- Phosphorylation of G Protein-Coupled Receptors: From the Barcode Hypothesis to the Flute Model
- (2017) Zhao Yang et al. MOLECULAR PHARMACOLOGY
- Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer
- (2017) Larissa Kistner et al. Oncotarget
- Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients
- (2016) Niels Halama et al. CANCER CELL
- Inflammation-Induced CCR7 Oligomers Form Scaffolds to Integrate Distinct Signaling Pathways for Efficient Cell Migration
- (2016) Mark A. Hauser et al. IMMUNITY
- Molecular Basis of Chemokine CXCL5-Glycosaminoglycan Interactions
- (2016) Krishna Mohan Sepuru et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Common and biased signaling pathways of the chemokine receptor CCR7 elicited by its ligands CCL19 and CCL21 in leukocytes
- (2016) M. A. Hauser et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Differential CCR7 Targeting in Dendritic Cells by Three Naturally Occurring CC-Chemokines
- (2016) Gertrud M. Hjortø et al. Frontiers in Immunology
- Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions
- (2016) Kirti V. Sawant et al. Scientific Reports
- Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions
- (2015) P. R. B. Joseph et al. BIOCHEMICAL JOURNAL
- “Chemokine receptors as therapeutic targets: Why aren’t there more drugs?”
- (2015) Roberto Solari et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies
- (2015) Irina Kufareva et al. IMMUNOLOGY AND CELL BIOLOGY
- Dual Targeting of the Chemokine Receptors CXCR4 and ACKR3 with Novel Engineered Chemokines
- (2015) Melinda S. Hanes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Application of BRET to monitor ligand binding to GPCRs
- (2015) Leigh A Stoddart et al. NATURE METHODS
- Polysialylation controls dendritic cell trafficking by regulating chemokine recognition
- (2015) E. Kiermaier et al. SCIENCE
- Differential ligand-signaling network of CCL19/CCL21-CCR7 system
- (2015) Rajesh Raju et al. Database-The Journal of Biological Databases and Curation
- Novel insights into G protein and G protein-coupled receptor signaling in cancer
- (2014) Morgan O’Hayre et al. CURRENT OPINION IN CELL BIOLOGY
- New nomenclature for atypical chemokine receptors
- (2014) Françoise Bachelerie et al. NATURE IMMUNOLOGY
- Dynamic conformational switching in the chemokine ligand is essential for G-protein-coupled receptor activation
- (2013) Prem Raj B. Joseph et al. BIOCHEMICAL JOURNAL
- Signalling bias in new drug discovery: detection, quantification and therapeutic impact
- (2013) Terry Kenakin et al. NATURE REVIEWS DRUG DISCOVERY
- CXCR4 Expression in Prostate Cancer Progenitor Cells
- (2012) Anna Dubrovska et al. PLoS One
- Receptor-Heteromer Investigation Technology and its application using BRET
- (2012) Elizabeth K. M. Johnstone et al. Frontiers in Endocrinology
- Maximal T Cell-Mediated Antitumor Responses Rely upon CCR5 Expression in Both CD4+ and CD8+ T Cells
- (2011) A. Gonzalez-Martin et al. CANCER RESEARCH
- CXCR7/CXCR4 Heterodimer Constitutively Recruits β-Arrestin to Enhance Cell Migration
- (2011) Fabien M. Décaillot et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The monomer-dimer equilibrium and glycosaminoglycan interactions of chemokine CXCL8 regulate tissue-specific neutrophil recruitment
- (2011) Pavani Gangavarapu et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways
- (2011) L. J. Drury et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distinct Phosphorylation Sites on the 2-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of -Arrestin
- (2011) K. N. Nobles et al. Science Signaling
- Site-specific Phosphorylation of CXCR4 Is Dynamically Regulated by Multiple Kinases and Results in Differential Modulation of CXCR4 Signaling
- (2010) John M. Busillo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
- (2009) D. A. Zidar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The exploration of macrocycles for drug discovery — an underexploited structural class
- (2008) Edward M. Driggers et al. NATURE REVIEWS DRUG DISCOVERY
- Structural Basis of CXCR4 Sulfotyrosine Recognition by the Chemokine SDF-1/CXCL12
- (2008) C. T. Veldkamp et al. Science Signaling
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