Berberine suppresses bladder cancer cell proliferation by inhibiting JAK1-STAT3 signaling via upregulation of miR-17-5p

Circular RNA AKT3 governs malignant behaviors of esophageal cancer cells by sponging miR-17-5p

(2021) Hong-Liang Zang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Inhibition of urinary bladder cancer cell proliferation by silibinin

(2020) Tatiane M. B. Barros et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

The CUL4B-miR-372/373-PIK3CA-AKT axis regulates metastasis in bladder cancer

(2020) Xiaochen Liu et al.   ONCOGENE

Berberine in the treatment of metabolism-related chronic diseases: A drug cloud (dCloud) effect to target multifactorial disorders

(2020) Wei-Jia Kong et al.   PHARMACOLOGY & THERAPEUTICS

miR‐17‐5p reduces inflammation and bone erosions in collagen induced arthritis mice and directly targets the JAK‐STAT pathway in rheumatoid arthritis fibroblast‐like synoviocytes

(2020) Aurélie Najm et al.   Arthritis & Rheumatology

Wogonin Induces Apoptosis and Reverses Sunitinib Resistance of Renal Cell Carcinoma Cells via Inhibiting CDK4-RB Pathway

(2020) Yong Wang et al.   Frontiers in Pharmacology

Targeting Stat3 signaling impairs the progression of bladder cancer in a mouse model

(2020) Jelena Korac-Prlic et al.   CANCER LETTERS

DANCR Promotes Metastasis and Proliferation in Bladder Cancer Cells by Enhancing IL-11-STAT3 Signaling and CCND1 Expression

(2019) Ziyue Chen et al.   MOLECULAR THERAPY

Berberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytes

(2019) Shuna Sun et al.   Cell Death & Disease

Protective effects of berberine hydrochloride on DSS-induced ulcerative colitis in rats

(2019) Lei Zhu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Metformin induces human esophageal carcinoma cell pyroptosis by targeting the miR-497/PELP1 axis

(2019) Lu Wang et al.   CANCER LETTERS

Erdafitinib in Locally Advanced or Metastatic Urothelial Carcinoma

(2019) Yohann Loriot et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modulation of the IL-6-Signaling Pathway in Liver Cells by miRNAs Targeting gp130, JAK1, and/or STAT3

(2019) Florence A. Servais et al.   Molecular Therapy-Nucleic Acids

Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin

(2019) Dong Eun Kim et al.   AGING CELL

Clinical outcome after progressing to frontline and second-line Anti–PD-1/PD-L1 in advanced urothelial cancer

(2019) Alfonso Gómez de Liaño Lista et al.   EUROPEAN UROLOGY

EAU-ESMO Consensus Statements on the Management of Advanced and Variant Bladder Cancer—An International Collaborative Multistakeholder Effort†

(2019) J. Alfred Witjes et al.   EUROPEAN UROLOGY

Silencing of CXCL12 performs a protective effect on C5b-9-induced injury in podocytes

(2018) Wengang Sha et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

PEITC Promotes Neurite Growth in Primary Sensory Neurons via the miR-17-5p/STAT3/GAP-43 Axis

(2018) Zhijie Wang et al.   JOURNAL OF DRUG TARGETING

Berberine inhibits growth and inflammatory invasive phenotypes of ectopic stromal cells: Imply the possible treatment of adenomyosis

(2018) Li Liu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

MP78-07 CLINICAL CHARACTERISTICS ASSOCIATED WITH EARLY PROGRESSION OR LONG-TERM RESPONSE FROM THE PHASE II IMVIGOR210 STUDY: ATEZOLIZUMAB IN LOCALLY ADVANCED OR METASTATIC UROTHELIAL CARCINOMA

(2018) Richard W. Joseph et al.   JOURNAL OF UROLOGY

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

(2018) Daniel E. Johnson et al.   Nature Reviews Clinical Oncology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

miR-17-5p-CXCL14 axis related transcriptome profile and clinical outcome in diffuse gliomas

(2018) Ailiang Zeng et al.   OncoImmunology

PTENP1 inhibits the growth of esophageal squamous cell carcinoma by regulating SOCS6 expression and correlates with disease prognosis

(2017) Tuotuo Gong et al.   MOLECULAR CARCINOGENESIS

The Circular RNA Interacts with STAT3, Increasing Its Nuclear Translocation and Wound Repair by Modulating Dnmt3a and miR-17 Function

(2017) Zhen-Guo Yang et al.   MOLECULAR THERAPY

STAT3 is required for MiR-17-5p-mediated sensitization to chemotherapy-induced apoptosis in breast cancer cells

(2017) Xing-Hua Liao et al.   Oncotarget

JAK-mediated autophagy regulates stemness and cell survival in cisplatin resistant bladder cancer cells

(2016) R. Ojha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Protective mechanisms of berberine against experimental autoimmune myocarditis in a rat model

(2016) Xuefei Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

GFRα2 prompts cell growth and chemoresistance through down-regulating tumor suppressor gene PTEN via Mir-17-5p in pancreatic cancer

(2016) Jiangning Gu et al.   CANCER LETTERS

Inhibition of the EGFR/STAT3/CEBPD Axis Reverses Cisplatin Cross-resistance with Paclitaxel in the Urothelial Carcinoma of the Urinary Bladder

(2016) Wei-Jan Wang et al.   CLINICAL CANCER RESEARCH

KCa1.1, a calcium-activated potassium channel subunit alpha 1, is targeted by miR-17-5p and modulates cell migration in malignant pleural mesothelioma

(2016) Yuen Yee Cheng et al.   Molecular Cancer

Berberine exerts an anti-inflammatory role in ocular Behcet's disease

(2016) Yan Yang et al.   Molecular Medicine Reports

Berberine inhibits EGFR signaling and enhances the antitumor effects of EGFR inhibitors in gastric cancer

(2016) Junxiong Wang et al.   Oncotarget

The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention

(2015) John J. O'Shea et al.   Annual Review of Medicine

Metformin can block precancerous progression to invasive tumors of bladder through inhibiting STAT3-mediated signaling pathways

(2015) Qi Pan et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Targeted therapies in bladder cancer: an overview of in vivo research

(2015) Kim E. M. van Kessel et al.   Nature Reviews Urology

Cytoplasmic p27 promotes epithelial–mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation

(2015) D Zhao et al.   ONCOGENE

Berberine may rescue Fusobacterium nucleatum-induced colorectal tumorigenesis by modulating the tumor microenvironment

(2015) Ya-Nan Yu et al.   Oncotarget

By Targeting Stat3 microRNA-17-5p Promotes Cardiomyocyte Apoptosis in Response to Ischemia Followed by Reperfusion

(2014) Weijie Du et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MicroRNAs in Cancer

(2013) Gianpiero Di Leva et al.   Annual Review of Pathology-Mechanisms of Disease

Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts

(2013) Chi Man Tsang et al.   BMC CANCER

Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion

(2013) Xiangling Yang et al.   NUCLEIC ACIDS RESEARCH

Stat3 Activation in Urothelial Stem Cells Leads to Direct Progression to Invasive Bladder Cancer

(2012) P. L. Ho et al.   CANCER RESEARCH

MiR-17-5p targets TP53INP1 and regulates cell proliferation and apoptosis of cervical cancer cells

(2012) Qian Wei et al.   IUBMB LIFE

Berberine inhibits the migration and invasion of T24 bladder cancer cells via reducing the expression of heparanase

(2012) Lei Yan et al.   TUMOR BIOLOGY

MicroRNAs as Regulators of Signal Transduction in Urological Tumors

(2011) A. Fendler et al.   CLINICAL CHEMISTRY

Berberine as a Promising Safe Anti-Cancer Agent- Is there a Role for Mitochondria?

(2011) Catia V. Diogo et al.   CURRENT DRUG TARGETS

Induction of G1 cell cycle arrest and apoptosis by berberine in bladder cancer cells

(2011) Keqiang Yan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Germline deletion of the miR-17∼92 cluster causes skeletal and growth defects in humans

(2011) Loïc de Pontual et al.   NATURE GENETICS

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL