Cytoplasmic p27 promotes epithelial–mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation

Oncogenic roles of EMT-inducing transcription factors

(2014) Alain Puisieux et al.   NATURE CELL BIOLOGY

PI3K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy

(2013) Seth A. Wander et al.   BREAST CANCER RESEARCH AND TREATMENT

p27Kip1 Directly Represses Sox2 during Embryonic Stem Cell Differentiation

(2012) Han Li et al.   Cell Stem Cell

High cytoplasmic expression of p27Kip1 is associated with a worse cancer-specific survival in clear cell renal cell carcinoma

(2011) Stephan Kruck et al.   BJU INTERNATIONAL

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

The cell cycle inhibitor p27Kip1controls self-renewal and pluripotency of human embryonic stem cells by regulating the cell cycle,BrachyuryandTwist

(2011) Cristina Menchón et al.   CELL CYCLE

Roles of STAT3 and ZEB1 Proteins in E-cadherin Down-regulation and Human Colorectal Cancer Epithelial-Mesenchymal Transition

(2011) Hua Xiong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

(2011) Lauren L.C. Marotta et al.   JOURNAL OF CLINICAL INVESTIGATION

p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes

(2011) R Pippa et al.   ONCOGENE

Cytoplasmic p27 is oncogenic and cooperates with Ras both in vivo and in vitro

(2011) M P Serres et al.   ONCOGENE

Phosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle control

(2011) H Jäkel et al.   ONCOGENE

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

p27: A Barometer of Signaling Deregulation and Potential Predictor of Response to Targeted Therapies

(2010) S. A. Wander et al.   CLINICAL CANCER RESEARCH

Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression

(2010) Douglas S. Micalizzi et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

TWISTing an embryonic transcription factor into an oncoprotein

(2010) S Ansieau et al.   ONCOGENE

A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers

(2010) Bryan T. Hennessy et al.   Clinical Proteomics

Tumor Self-Seeding by Circulating Cancer Cells

(2009) Mi-Young Kim et al.   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

STAT3 as a Central Regulator of Tumor Metastases

(2009) Eswaran Devarajan et al.   CURRENT MOLECULAR MEDICINE

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility

(2009) M. D. Larrea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAT3 can be activated through paracrine signaling in breast epithelial cells

(2008) Jacqueline C Lieblein et al.   BMC CANCER

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

Twist Is Transcriptionally Induced by Activation of STAT3 and Mediates STAT3 Oncogenic Function

(2008) George Z. Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR-Raptor Binds and Activates SGK1 to Regulate p27 Phosphorylation

(2008) Feng Hong et al.   MOLECULAR CELL

Molecular Basis of Metastasis

(2008) Anne C. Chiang et al.   NEW ENGLAND JOURNAL OF MEDICINE