Structure and function of aerotolerant, multiple-turnover THI4 thiazole synthases

The number of catalytic cycles in an enzyme’s lifetime and why it matters to metabolic engineering

(2021) Andrew D. Hanson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems for in vivo hypermutation: a quest for scale and depth in directed evolution

(2021) Gordon Rix et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Structure, function, and biosynthesis of nickel‐dependent enzymes

(2020) Marila Alfano et al.   PROTEIN SCIENCE

Bioinformatic and experimental evidence for suicidal and catalytic plant THI4s

(2020) Jaya Joshi et al.   BIOCHEMICAL JOURNAL

Enzymes as Parts in Need of Replacement – and How to Extend Their Working Life

(2020) Nathan D. Tivendale et al.   TRENDS IN PLANT SCIENCE

Potential for Applying Continuous Directed Evolution to Plant Enzymes: An Exploratory Study

(2020) Jorge D. García-García et al.   Life-Basel

Fluid geochemistry, local hydrology, and metabolic activity define methanogen community size and composition in deep-sea hydrothermal vents

(2019) Lucy C. Stewart et al.   ISME Journal

Protein crystal structure determination with the crystallophore, a nucleating and phasing agent

(2019) Sylvain Engilberge et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

The EFI Web Resource for Genomic Enzymology Tools: Leveraging Protein, Genome, and Metagenome Databases to Discover Novel Enzymes and Metabolic Pathways

(2019) Rémi Zallot et al.   BIOCHEMISTRY

Nickel–pincer nucleotide cofactor

(2018) Robert P Hausinger et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Redesigning thiamin synthesis: Prospects and potential payoffs

(2018) Andrew D. Hanson et al.   PLANT SCIENCE

Tracking the route of molecular oxygen in O2-tolerant membrane-bound [NiFe] hydrogenase

(2018) Jacqueline Kalms et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parts-prospecting For a High-efficiency Thiamin Thiazole Biosynthesis Pathway

(2018) Jiayi Sun et al.   PLANT PHYSIOLOGY

Oxygen activation by mononuclear nonheme iron dioxygenases involved in the degradation of aromatics

(2017) Yifan Wang et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Protein Degradation Rate in Arabidopsis thaliana Leaf Growth and Development

(2017) Lei Li et al.   PLANT CELL

Insight into the evolution of microbial metabolism from the deep-branching bacterium, Thermovibrio ammonificans

(2017) Donato Giovannelli et al.   eLife

Krypton Derivatization of an O2-Tolerant Membrane-Bound [NiFe] Hydrogenase Reveals a Hydrophobic Tunnel Network for Gas Transport

(2016) Jacqueline Kalms et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Basis for Iron-Mediated Sulfur Transfer in Archael and Yeast Thiazole Synthases

(2016) Xuan Zhang et al.   BIOCHEMISTRY

Oxygen activation by mononuclear Mn, Co, and Ni centers in biology and synthetic complexes

(2016) Adam T. Fiedler et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

From Suicide Enzyme to Catalyst: The Iron-Dependent Sulfide Transfer in Methanococcus jannaschii Thiamin Thiazole Biosynthesis

(2016) Bekir E. Eser et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The cytochromebdoxidase ofEscherichia coliprevents respiratory inhibition by endogenous and exogenous hydrogen sulfide

(2016) Sergey Korshunov et al.   MOLECULAR MICROBIOLOGY

Does Abiotic Stress Cause Functional B Vitamin Deficiency in Plants?

(2016) Andrew D. Hanson et al.   PLANT PHYSIOLOGY

Enzyme Function Initiative-Enzyme Similarity Tool (EFI-EST): A web tool for generating protein sequence similarity networks

(2015) John A. Gerlt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Functional expression of a heterologous nickel-dependent, ATP-independent urease in Saccharomyces cerevisiae

(2015) N. Milne et al.   METABOLIC ENGINEERING

Yap1 mediates tolerance to cobalt toxicity in the yeast Saccharomyces cerevisiae

(2014) Catarina Pimentel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

UniRef clusters: a comprehensive and scalable alternative for improving sequence similarity searches

(2014) B. E. Suzek et al.   BIOINFORMATICS

Conserved active site cysteine residue of archaeal THI4 homolog is essential for thiamine biosynthesis in Haloferax volcanii

(2014) Sungmin Hwang et al.   BMC MICROBIOLOGY

Cysteinate Protonation and Water Hydrogen Bonding at the Active-Site of a Nickel Superoxide Dismutase Metallopeptide-Based Mimic: Implications for the Mechanism of Superoxide Reduction

(2014) Jason Shearer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Proteins with High Turnover Rate in Barley Leaves Estimated by Proteome Analysis Combined with in Planta Isotope Labeling

(2014) Clark J. Nelson et al.   PLANT PHYSIOLOGY

Expanding the paradigm of thiol redox in the thermophilic root of life

(2013) Joshua Heinemann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Molecular Characterization of Copper and Cadmium Resistance Determinants in the Biomining Thermoacidophilic ArchaeonSulfolobus metallicus

(2013) Alvaro Orell et al.   ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Thiamin biosynthesis: still yielding fascinating biological chemistry

(2012) Tadhg P. Begley et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Structure-based replacement of methionine residues at the catalytic domains with serine significantly improves the oxidative stability of alkaline amylase from alkaliphilicAlkalimonas amylolytica

(2012) Haiquan Yang et al.   BIOTECHNOLOGY PROGRESS

The Mercury Resistance Operon: From an Origin in a Geothermal Environment to an Efficient Detoxification Machine

(2012) Eric S. Boyd et al.   Frontiers in Microbiology

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase

(2011) Abhishek Chatterjee et al.   NATURE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Redox Regulation of SCO Protein Function: Controlling Copper at a Mitochondrial Crossroad

(2010) Scot C. Leary   ANTIOXIDANTS & REDOX SIGNALING

electronic Ligand Builder and Optimization Workbench(eLBOW): a tool for ligand coordinate and restraint generation

(2009) Nigel W. Moriarty et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Comparative genomic analyses of nickel, cobalt and vitamin B12 utilization

(2009) Yan Zhang et al.   BMC GENOMICS

Zinc Binding in Pestivirus Npro Is Required for Interferon Regulatory Factor 3 Interaction and Degradation

(2009) Michal R. Szymanski et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification and Characterization of a Bacterial Glycerol-1-phosphate Dehydrogenase: Ni2+-Dependent AraM fromBacillus subtilis†

(2008) Harald Guldan et al.   BIOCHEMISTRY

Special issue: Redox regulation of protein folding

(2008) Johannes M. Herrmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH