Emerging role of Tissue Resident Memory T cells in vitiligo: From pathogenesis to therapeutics

Tumor Necrosis Factor-alpha affects melanocyte survival and melanin synthesis via multiple pathways in vitiligo

(2021) Mala Singh et al.   CYTOKINE

Vitiligo: Mechanisms of Pathogenesis and Treatment

(2020) Michael L. Frisoli et al.   Annual Review of Immunology

Tissue-resident memory T cells in the skin

(2020) Samar Khalil et al.   INFLAMMATION RESEARCH

Developmental plasticity allows outside-in immune responses by resident memory T cells

(2020) Raissa Fonseca et al.   NATURE IMMUNOLOGY

Tissue-resident memory T cells in breast cancer control and immunotherapy responses

(2020) Ann Byrne et al.   Nature Reviews Clinical Oncology

Altered expression of nuclear factor of activated T cells, forkhead box P3, and immune‐suppressive genes in regulatory T cells of generalized vitiligo patients

(2020) Prashant S. Giri et al.   Pigment Cell & Melanoma Research

Perivascular tissue resident memory T cells as therapeutic target in multiple sclerosis

(2020) Joost Smolders et al.   Expert Review of Neurotherapeutics

The Role of TRM Cells in the Pathogenesis of Vitiligo—A Review of the Current State-Of-The-Art

(2020) Alicja Frączek et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

P19 Frequencies of IL-17+CD8+ T-cells and tissue resident memory T-cells in early inflammatory arthritis

(2020) Catherine D Hughes et al.   RHEUMATOLOGY

CD4+ Resident Memory T Cells Mediate Long-Term Local Skin Immune Memory of Contact Hypersensitivity in BALB/c Mice

(2020) Akihiko Murata et al.   Frontiers in Immunology

Decreased suppression of CD8 + and CD4 + T cells by peripheral regulatory T cells in generalized vitiligo due to reduced NFATC1 and FOXP3 proteins

(2020) Prashant S. Giri et al.   EXPERIMENTAL DERMATOLOGY

CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response

(2020) Shannon K. Bromley et al.   Cell Reports

Origins of CD 4 + circulating and tissue‐resident memory T cells

(2019) Quynh P. Nguyen et al.   IMMUNOLOGY

Juvenile polyautoimmunity in a rheumatology setting

(2019) Clara Malagón et al.   AUTOIMMUNITY REVIEWS

Polyphenols in the treatment of autoimmune diseases

(2019) Haroon Khan et al.   AUTOIMMUNITY REVIEWS

The Role of Memory CD8+ T Cells in Vitiligo

(2019) Rebecca L. Riding et al.   JOURNAL OF IMMUNOLOGY

The Functional Requirement for CD69 in Establishment of Resident Memory CD8+ T Cells Varies with Tissue Location

(2019) Daniel A. Walsh et al.   JOURNAL OF IMMUNOLOGY

Skin‐resident memory T cells as a potential new therapeutic target in vitiligo and melanoma

(2019) Marcella Willemsen et al.   Pigment Cell & Melanoma Research

The Roles of Liver-Resident Lymphocytes in Liver Diseases

(2019) Yanan Wang et al.   Frontiers in Immunology

Pathogenic role of tissue-resident memory T cells in autoimmune diseases

(2018) Haijing Wu et al.   AUTOIMMUNITY REVIEWS

CD103+Tumor-Resident CD8+T Cells Are Associated with Improved Survival in Immunotherapy-Naïve Melanoma Patients and Expand Significantly During Anti–PD-1 Treatment

(2018) Jarem Edwards et al.   CLINICAL CANCER RESEARCH

The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis -Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation

(2018) Dapeng Wang et al.   IMMUNITY

Vitiligo Skin Is Imprinted with Resident Memory CD8 T Cells Expressing CXCR3

(2018) Katia Boniface et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo

(2018) Jillian M. Richmond et al.   Science Translational Medicine

Identifying off-target effects of etomoxir reveals that carnitine palmitoyltransferase I is essential for cancer cell proliferation independent of β-oxidation

(2018) Cong-Hui Yao et al.   PLOS BIOLOGY

Metabolic Reprogramming and Longevity of Tissue-Resident Memory T Cells

(2018) Youdong Pan et al.   Frontiers in Immunology

Blimp-1 induces and Hobit maintains the cytotoxic mediator granzyme B in CD8 T cells

(2018) Natasja A.M. Kragten et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A skewed pool of resident T cells triggers psoriasis-associated tissue responses in never-lesional psoriasis skin

(2018) Irène Gallais Sérézal et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CD8+ Resident Memory T Cells and Viral Infection

(2018) Xuejie Wu et al.   Frontiers in Immunology

Resident memory and recirculating memory T cells cooperate to maintain disease in a mouse model of vitiligo

(2018) Jillian M. Richmond et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Lymphoid Stress Surveillance Response Contributes to Vitiligo Pathogenesis

(2018) Liisi Raam et al.   Frontiers in Immunology

CD4+ Memory T Cells at Home in the Tissue: Mechanisms for Health and Disease

(2018) David Schreiner et al.   Frontiers in Immunology

Resident-Memory T Cells in Tissue-Restricted Immune Responses: For Better or Worse?

(2018) Karin Steinbach et al.   Frontiers in Immunology

CD49a Expression Defines Tissue-Resident CD8 + T Cells Poised for Cytotoxic Function in Human Skin

(2017) Stanley Cheuk et al.   IMMUNITY

Staged development of long-lived T-cell receptor αβ T H 17 resident memory T-cell population to Candida albicans after skin infection

(2017) Chang Ook Park et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CXCR3 Depleting Antibodies Prevent and Reverse Vitiligo in Mice

(2017) Jillian M. Richmond et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-15 supports the generation of protective lung-resident memory CD4 T cells

(2017) T M Strutt et al.   Mucosal Immunology

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

(2017) Youdong Pan et al.   NATURE

Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours

(2017) J. Justin Milner et al.   NATURE

Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells

(2017) Michel Enamorado et al.   Nature Communications

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Skin-resident CD4+ T cells protect against Leishmania major by recruiting and activating inflammatory monocytes

(2017) Nelson D. Glennie et al.   PLoS Pathogens

Increased expression of CXCR3 and its ligands in patients with vitiligo and CXCL10 as a potential clinical marker for vitiligo

(2016) X. X. Wang et al.   BRITISH JOURNAL OF DERMATOLOGY

Understanding mechanisms of autoimmunity through translational research in vitiligo

(2016) James P Strassner et al.   CURRENT OPINION IN IMMUNOLOGY

The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis

(2016) Carmen Gerlach et al.   IMMUNITY

Resident memory T cells are a Notch above the rest

(2016) Sathi Wijeyesinghe et al.   NATURE IMMUNOLOGY

Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells

(2016) Pleun Hombrink et al.   NATURE IMMUNOLOGY

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

Microbial community profiling shows dysbiosis in the lesional skin of Vitiligo subjects

(2016) Parul Ganju et al.   Scientific Reports

Regulatory T cells in vitiligo: Implications for pathogenesis and therapeutics

(2015) Mitesh Dwivedi et al.   AUTOIMMUNITY REVIEWS

Tumour necrosis factor-α inhibition can stabilize disease in progressive vitiligo

(2015) K.C. Webb et al.   BRITISH JOURNAL OF DERMATOLOGY

Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B

(2015) Magali Grange et al.   IMMUNOLOGY

Persistent Antigen and Prolonged AKT–mTORC1 Activation Underlie Memory CD8 T Cell Impairment in the Absence of CD4 T Cells

(2015) Yingzhong Li et al.   JOURNAL OF IMMUNOLOGY

Transcriptional Analysis of Vitiligo Skin Reveals the Alteration of WNT Pathway: A Promising Target for Repigmenting Vitiligo Patients

(2015) Claire Regazzetti et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Maintenance Therapy of Adult Vitiligo with 0.1% Tacrolimus Ointment: A Randomized, Double Blind, Placebo–Controlled Study

(2015) Marine Cavalié et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma

(2015) Takeya Adachi et al.   NATURE MEDICINE

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

(2015) Rei Watanabe et al.   Science Translational Medicine

Type I interferon signature in the initiation of the immune response in vitiligo

(2014) Antoine Bertolotti et al.   Pigment Cell & Melanoma Research

Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert

(2014) S. Ariotti et al.   SCIENCE

CXCL10 Is Critical for the Progression and Maintenance of Depigmentation in a Mouse Model of Vitiligo

(2014) M. Rashighi et al.   Science Translational Medicine

Melanocyte-specific CD8+T cells are associated with epidermal depigmentation in a novel mouse model of vitiligo

(2013) S. You et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Vitiligo: interplay between oxidative stress and immune system

(2013) Naresh C. Laddha et al.   EXPERIMENTAL DERMATOLOGY

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse

(2012) D. Bobbala et al.   DIABETOLOGIA

IL-15 inhibits IL-7Rα expression by memory-phenotype CD8+T cells in the bone marrow

(2012) Angela C. Quinci et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-15 receptor α expression in inflammatory bowel disease patients before and after normalization of inflammation with infliximab

(2012) Clémentine Perrier et al.   IMMUNOLOGY

A review of the worldwide prevalence of vitiligo in children/adolescents and adults

(2012) Christian Krüger et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues

(2012) K. A. Casey et al.   JOURNAL OF IMMUNOLOGY

A Mouse Model of Vitiligo with Focused Epidermal Depigmentation Requires IFN-γ for Autoreactive CD8+ T-Cell Accumulation in the Skin

(2012) John E. Harris et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Increased Tumor Necrosis Factor (TNF)-α and Its Promoter Polymorphisms Correlate with Disease Progression and Higher Susceptibility towards Vitiligo

(2012) Naresh C. Laddha et al.   PLoS One

Vitiligo: A review of some facts lesser known about depigmentation

(2011) JamesJ Nordlund   INDIAN JOURNAL OF DERMATOLOGY

Interleukin-7 promotes the survival of human CD4+effector/memory T cells by up-regulating Bcl-2 proteins and activating the JAK/STAT signalling pathway

(2010) Nizar Chetoui et al.   IMMUNOLOGY

Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory

(2010) G. Jeannet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vitiligo is more than skin deep: a survey of members of the Vitiligo Society

(2009) N. Talsania et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Autoimmune Destruction of Skin Melanocytes by Perilesional T Cells from Vitiligo Patients

(2009) Jasper G. van den Boorn et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY