A high‐fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the App NL−F/NL−F knock‐in mouse model

Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers

(2020) Seyyed Abolghasem Ghadami et al.   BIOMACROMOLECULES

High fat diet worsens Alzheimer’s disease-related behavioral abnormalities and neuropathology in APP/PS1 mice, but not by synergistically decreasing cerebral blood flow

(2020) Oliver Bracko et al.   Scientific Reports

The Extracellular Protein, Transthyretin Is an Oxidative Stress Biomarker

(2019) Meesha Sharma et al.   Frontiers in Physiology

Differential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimer’s disease

(2019) Tomoko Wakabayashi et al.   Molecular Neurodegeneration

8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes

(2019) Naoki Haruyama et al.   PROGRESS IN NEUROBIOLOGY

Gender-specific effects of transthyretin on neural stem cell fate in the subventricular zone of the adult mouse

(2019) Pieter Vancamp et al.   Scientific Reports

Dementia

(2018) Seth A. Gale et al.   AMERICAN JOURNAL OF MEDICINE

High fat diet treatment impairs hippocampal long-term potentiation without alterations of the core neuropathological features of Alzheimer disease

(2018) Isabel H. Salas et al.   NEUROBIOLOGY OF DISEASE

8-Oxoguanine DNA glycosylase 1: Beyond repair of the oxidatively modified base lesions

(2018) Xueqing Ba et al.   Redox Biology

High-fat diet protects the blood-brain barrier in an Alzheimer's disease mouse model

(2018) Shirin Elhaik Goldman et al.   AGING CELL

Gender-Dependent Transthyretin Modulation of Brain Amyloid-β Levels: Evidence from a Mouse Model of Alzheimer's Disease

(2018) Sandra Marisa Oliveira et al.   JOURNAL OF ALZHEIMERS DISEASE

Plasma Transthyretin as a Candidate Marker for Alzheimer's Disease

(2018) Latha Velayudhan et al.   JOURNAL OF ALZHEIMERS DISEASE

Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer's disease

(2017) Jennifer M. Walker et al.   NEUROBIOLOGY OF DISEASE

Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

(2017) Erika Castillo et al.   Scientific Reports

Evaluation of Neuropathological Effects of a High-Fat Diet in a Presymptomatic Alzheimer’s Disease Stage in APP/PS1 Mice

(2016) Miren Ettcheto et al.   JOURNAL OF ALZHEIMERS DISEASE

Cognitive deficits in single App knock-in mouse models

(2016) Akira Masuda et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

An Overview of Murine High Fat Diet as a Model for Type 2 Diabetes Mellitus

(2016) Ahlke Heydemann   Journal of Diabetes Research

Molecular Mechanisms of Amyloid Oligomers Toxicity

(2016) Rakez Kayed et al.   JOURNAL OF ALZHEIMERS DISEASE

Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer’s disease

(2016) Sugako Oka et al.   Scientific Reports

Impaired cognition and cerebral glucose regulation are associated with astrocyte activation in the parenchyma of metabolically stressed APPswe/PS1dE9 mice

(2015) Chi-Wen Yeh et al.   NEUROBIOLOGY OF AGING

Effects of high-fat diet exposure on learning & memory

(2015) Zachary A. Cordner et al.   PHYSIOLOGY & BEHAVIOR

Neuropathology and biochemistry of Aβ and its aggregates in Alzheimer’s disease

(2014) Dietmar Rudolf Thal et al.   ACTA NEUROPATHOLOGICA

Diabetes Mellitus and Dementia

(2014) Toshiharu Ninomiya   Current Diabetes Reports

Insulin Reverses the High-Fat Diet-Induced Increase in Brain A  and Improves Memory in an Animal Model of Alzheimer Disease

(2014) M. Vandal et al.   DIABETES

Type 3 diabetes is sporadic Alzheimer׳s disease: Mini-review

(2014) Suzanne M. de la Monte   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Single App knock-in mouse models of Alzheimer's disease

(2014) Takashi Saito et al.   NATURE NEUROSCIENCE

High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology

(2014) Elysse M. Knight et al.   NEUROBIOLOGY OF AGING

Sex-Specific Effects of High Fat Diet on Indices of Metabolic Syndrome in 3xTg-AD Mice: Implications for Alzheimer's Disease

(2013) Anna M. Barron et al.   PLoS One

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

(2012) K. D. Copps et al.   DIABETOLOGIA

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transthyretin and the brain re-visited: Is neuronal synthesis of transthyretin protective in Alzheimer's disease?

(2011) Xinyi Li et al.   Molecular Neurodegeneration

Insulin resistance is associated with the pathology of Alzheimer disease: The Hisayama Study

(2010) T. Matsuzaki et al.   NEUROLOGY

Western diet consumption and cognitive impairment: Links to hippocampal dysfunction and obesity

(2010) Scott E. Kanoski et al.   PHYSIOLOGY & BEHAVIOR

Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of A  toxicity

(2008) J. N. Buxbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic plasticity, memory and the hippocampus: a neural network approach to causality

(2007) Guilherme Neves et al.   NATURE REVIEWS NEUROSCIENCE