Neuronal chemokine-like-factor 1 (CKLF1) up-regulation promotes M1 polarization of microglia in rat brain after stroke

Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke

(2020) Yves Werner et al.   NATURE NEUROSCIENCE

Hyperacute Management of Ischemic Strokes

(2020) Pratit Patel et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Potential circadian effects on translational failure for neuroprotection

(2020) Elga Esposito et al.   NATURE

Bromodomain-containing protein 9 promotes the growth and metastasis of human hepatocellular carcinoma by activating the TUFT1/AKT pathway

(2020) Changwei Dou et al.   Cell Death & Disease

CKLF1 Aggravates Focal Cerebral Ischemia Injury at Early Stage Partly by Modulating Microglia/Macrophage Toward M1 Polarization Through CCR4

(2019) Chen Chen et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

IMM-H004 protects against oxygen-glucose deprivation/reperfusion injury to BV2 microglia partly by modulating CKLF1 involved in microglia polarization

(2019) Chen Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

IMM-H004 Therapy for Permanent Focal Ischemic Cerebral Injury via CKLF1/CCR4-mediated NLRP3 Inflammasome Activation

(2019) QI-DI AI et al.   Translational Research

Microglia-derived TNF-α mediates endothelial necroptosis aggravating blood brain–barrier disruption after ischemic stroke

(2019) An-Qi Chen et al.   Cell Death & Disease

IL-10 produces a dual effect on OGD-induced neuronal apoptosis of cultured cortical neurons via the NF-κB pathway

(2019) Hongbin Chen et al.   Aging-US

Protecting the ischaemic penumbra as an adjunct to thrombectomy for acute stroke

(2018) Jean-Claude Baron   Nature Reviews Neurology

Multipoint targeting of TGF-β/Wnt transactivation circuit with microRNA 384-5p for cardiac fibrosis

(2018) Hyang-Hee Seo et al.   CELL DEATH AND DIFFERENTIATION

Diabetes Mellitus Impairs White Matter Repair and Long-Term Functional Deficits After Cerebral Ischemia

(2018) Shubei Ma et al.   STROKE

The far-reaching scope of neuroinflammation after traumatic brain injury

(2017) Dennis W. Simon et al.   Nature Reviews Neurology

Modulators of microglial activation and polarization after intracerebral haemorrhage

(2017) Xi Lan et al.   Nature Reviews Neurology

IMM-H004, a coumarin derivative, attenuated brain ischemia/reperfusion injuries and subsequent inflammation in spontaneously hypertensive rats through inhibition of VCAM-1

(2017) Peng-Fei Yang et al.   RSC Advances

Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke

(2016) Johanna Rodhe et al.   Acta Neuropathologica Communications

Microglia in action: how aging and injury can change the brain’s guardians

(2015) Athanasios Lourbopoulos et al.   Frontiers in Cellular Neuroscience

Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis

(2015) Rachel J. Roth Flach et al.   Nature Communications

The chemokine-like factor 1 induces asthmatic pathological change by activating nuclear factor-κB signaling pathway

(2014) Gang Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Neutralization of chemokine-like factor 1, a novel C-C chemokine, protects against focal cerebral ischemia by inhibiting neutrophil infiltration via MAPK pathways in rats

(2014) Ling Kong et al.   Journal of Neuroinflammation

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

The p38  MAPK Regulates Microglial Responsiveness to Diffuse Traumatic Brain Injury

(2013) A. D. Bachstetter et al.   JOURNAL OF NEUROSCIENCE

Minimal NF-κB activity in neurons

(2013) S.J. Listwak et al.   NEUROSCIENCE

Caspase blockade induces RIP3-mediated programmed necrosis in Toll-like receptor-activated microglia

(2013) S J Kim et al.   Cell Death & Disease

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ)

(2011) Adam D Bachstetter et al.   Journal of Neuroinflammation

CCL2 Released from Neuronal Synaptic Vesicles in the Spinal Cord Is a Major Mediator of Local Inflammation and Pain after Peripheral Nerve Injury

(2011) J. Van Steenwinckel et al.   JOURNAL OF NEUROSCIENCE

Microglial p38α MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFα

(2011) Bin Xing et al.   Molecular Neurodegeneration

Expression of chemokine-like factor 1 after focal cerebral ischemia in the rat

(2011) Ling-Lei Kong et al.   NEUROSCIENCE LETTERS

C19, a C-terminal peptide of chemokine-like factor 1, protects the brain against focal brain ischemia in rats

(2011) Ling-Lei Kong et al.   NEUROSCIENCE LETTERS

NF-κB and innate immunity in ischemic stroke

(2010) Olivier A. Harari et al.   Annals of the New York Academy of Sciences

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

(2010) Martin Fuhrmann et al.   NATURE NEUROSCIENCE

NF-κB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia

(2008) Ilenia Sarnico et al.   JOURNAL OF NEUROCHEMISTRY

Neuron-microglia signaling: Chemokines as versatile messengers

(2008) K. Biber et al.   JOURNAL OF NEUROIMMUNOLOGY

A Dual Role of the NF-κB Pathway in Neonatal Hypoxic-Ischemic Brain Damage

(2008) Cora H. Nijboer et al.   STROKE