Guanidine Derivatives: How Simple Structural Modification of Histamine H3R Antagonists Has Led to the Discovery of Potent Muscarinic M2R/M4R Antagonists

Evolutionary history of histamine receptors: Early vertebrate origin and expansion of the H3-H4 subtypes

(2020) Infant Sagayaraj Ravhe et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

4-Hydroxypiperidines and Their Flexible 3-(Amino)propyloxy Analogues as Non-Imidazole Histamine H3 Receptor Antagonist: Further Structure–Activity Relationship Exploration and In Vitro and In Vivo Pharmacological Evaluation

(2018) Beata Olszewska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aminergic GPCR–Ligand Interactions: A Chemical and Structural Map of Receptor Mutation Data

(2018) Márton Vass et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural insights into the subtype-selective antagonist binding to the M2 muscarinic receptor

(2018) Ryoji Suno et al.   Nature Chemical Biology

PlayMolecule ProteinPrepare: A Web Application for Protein Preparation for Molecular Dynamics Simulations

(2017) Gerard Martínez-Rosell et al.   Journal of Chemical Information and Modeling

GPCRdb in 2018: adding GPCR structure models and ligands

(2017) Gáspár Pándy-Szekeres et al.   NUCLEIC ACIDS RESEARCH

Hybrid approach to structure modeling of the histamine H3 receptor: Multi-level assessment as a tool for model verification

(2017) Jakub Jończyk et al.   PLoS One

Characterization of PCS1055, a novel muscarinic M4 receptor antagonist

(2016) Carrie H. Croy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Crystal structures of the M1 and M4 muscarinic acetylcholine receptors

(2016) David M. Thal et al.   NATURE

Social Information Signaling by Neurons in Primate Striatum

(2013) Jeffrey T. Klein et al.   CURRENT BIOLOGY

Molecular Basis for the Long Duration of Action and Kinetic Selectivity of Tiotropium for the Muscarinic M3 Receptor

(2013) Christofer S. Tautermann et al.   JOURNAL OF MEDICINAL CHEMISTRY

Social Play Behavior in Adolescent Rats is Mediated by Functional Activity in Medial Prefrontal Cortex and Striatum

(2013) Linda WM van Kerkhof et al.   NEUROPSYCHOPHARMACOLOGY

Advances in the pharmacological treatment of Parkinson's disease: targeting neurotransmitter systems

(2013) Lars Brichta et al.   TRENDS IN NEUROSCIENCES

Synthesis and Preliminary Pharmacological Investigation of NewN-Substituted-N-[ω-(ω-phenoxy-alkylpiperazin-1-yl)alkyl]guanidines as Non-Imidazole Histamine H3Antagonists

(2012) Marek Staszewski et al.   ARCHIV DER PHARMAZIE

Receptor-specific functional efficacies of alkyl imidazoles as dual histamine H3/H4 receptor ligands

(2011) Tim Kottke et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Muscarinic acetylcholine receptors as CNS drug targets

(2007) Christopher J. Langmead et al.   PHARMACOLOGY & THERAPEUTICS