Germline mutations in apoptosis pathway genes in ovarian cancer; the functional role of a TP53I3 (PIG3) variant in ROS production and DNA repair

FANCM, RAD1, CHEK1 and TP53I3 act as BRCA-like tumor suppressors and are mutated in hereditary ovarian cancer

(2019) Jaime L. Lopes et al.   Cancer Genetics

Ovarian cancer statistics, 2018

(2018) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Truncating mutations of TP53AIP1 gene predispose to cutaneous melanoma

(2018) Meriem Benfodda et al.   GENES CHROMOSOMES & CANCER

The Human Gene Mutation Database: towards a comprehensive repository of inherited mutation data for medical research, genetic diagnosis and next-generation sequencing studies

(2017) Peter D. Stenson et al.   HUMAN GENETICS

PIG3 promotes NSCLC cell mitotic progression and is associated with poor prognosis of NSCLC patients

(2017) Ming Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

ClinVar: improving access to variant interpretations and supporting evidence

(2017) Melissa J Landrum et al.   NUCLEIC ACIDS RESEARCH

Reanalysis of BRCA1/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability

(2017) Jaime L. Stafford et al.   PLoS One

Formation and Biological Targets of Quinones: Cytotoxic versus Cytoprotective Effects

(2016) Judy L. Bolton et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

PIG3 plays an oncogenic role in papillary thyroid cancer by activating the PI3K/AKT/PTEN pathway

(2015) JINYE XU et al.   ONCOLOGY REPORTS

BRCA1 regulates PIG3-mediated apoptosis in a p53-dependent manner

(2015) Wenwen Zhang et al.   Oncotarget

Diabetes mellitus and ovarian cancer: More complex than just increasing risk

(2014) Monjri M. Shah et al.   GYNECOLOGIC ONCOLOGY

BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells

(2014) Xuexia Zhou et al.   Nature Communications

Integrated analysis of germline and somatic variants in ovarian cancer

(2014) Krishna L. Kanchi et al.   Nature Communications

PIG3 Functions in DNA Damage Response through Regulating DNA-PKcs Homeostasis

(2013) Bing Li et al.   International Journal of Biological Sciences

American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology Screening Guidelines for the Prevention and Early Detection of Cervical Cancer

(2012) Debbie Saslow et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Prostate Cancer Risk Is not Altered by TP53AIP1 Germline Mutations in a German Case-Control Series

(2012) Manuel Luedeke et al.   PLoS One

BCLAF1 is a radiation-induced H2AX-interacting partner involved in γH2AX-mediated regulation of apoptosis and DNA repair

(2012) Y Y Lee et al.   Cell Death & Disease

Production and Detection of Reactive Oxygen Species (ROS) in Cancers

(2011) Danli Wu et al.   Jove-Journal of Visualized Experiments

Rare genetic variants and the risk of cancer

(2010) Walter Bodmer et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Combination of p53AIP1 and survivin expression is a powerful prognostic marker in non-small cell lung cancer

(2009) Shin-ichi Yamashita et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

The p53-inducible gene 3 (PIG3) contributes to early cellular response to DNA damage

(2009) J-H Lee et al.   ONCOGENE

Association of the PIK3C2G gene polymorphisms with type 2 DM in a Japanese population

(2007) Makoto Daimon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

p53AIP1 Expression can be a Prognostic Marker in Non-small Cell Lung Cancer

(2007) S.-i. Yamashita et al.   CLINICAL ONCOLOGY