The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR

Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis

(2020) Christina Gerstner et al.   BMC IMMUNOLOGY

Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts

(2019) Meng Sun et al.   ANNALS OF THE RHEUMATIC DISEASES

Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint

(2018) Jennifer Pieper et al.   JOURNAL OF AUTOIMMUNITY

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis

(2018) Yi Tian Ting et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantifiable predictive features define epitope-specific T cell receptor repertoires

(2017) Pradyot Dash et al.   NATURE

High-Titer Rheumatoid Arthritis Antibodies Preferentially Bind Fibrinogen Citrullinated by Peptidylarginine Deiminase 4

(2017) Nathalie E. Blachère et al.   Arthritis & Rheumatology

Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils

(2017) Yebin Zhou et al.   Frontiers in Immunology

Identification of citrullinated peptides in the synovial fluid of patients with rheumatoid arthritis using LC-MALDI-TOF/TOF

(2016) Fei Wang et al.   CLINICAL RHEUMATOLOGY

Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion

(2016) T. Delong et al.   SCIENCE

T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules

(2015) Jamie Rossjohn et al.   Annual Review of Immunology

Assessing the Citrullinome in Rheumatoid Arthritis Synovial Fluid with and without Enrichment of Citrullinated Peptides

(2014) Astrid E. V. Tutturen et al.   JOURNAL OF PROTEOME RESEARCH

T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease

(2014) Jan Petersen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Citrulline-Specific Th1 Cells Are Increased in Rheumatoid Arthritis and Their Frequency Is Influenced by Disease Duration and Therapy

(2014) Eddie A. James et al.   Arthritis & Rheumatology

The Adaptable Major Histocompatibility Complex (MHC) Fold: Structure and Function of Nonclassical and MHC Class I–Like Molecules

(2013) Erin J. Adams et al.   Annual Review of Immunology

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

(2013) Stephen W. Scally et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immune-Mediated Pore-Forming Pathways Induce Cellular Hypercitrullination and Generate Citrullinated Autoantigens in Rheumatoid Arthritis

(2013) V. Romero et al.   Science Translational Medicine

The rheumatoid arthritis synovial fluid citrullinome reveals novel citrullinated epitopes in apolipoprotein E, myeloid nuclear differentiation antigen, and β-actin

(2012) Joyce J. B. C. van Beers et al.   ARTHRITIS AND RHEUMATISM

Multifunctional T cell reactivity with native and glycosylated type II collagen in rheumatoid arthritis

(2012) Omri Snir et al.   ARTHRITIS AND RHEUMATISM

The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude

(2012) M. K. Jenkins et al.   JOURNAL OF IMMUNOLOGY

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

T Cell Receptor    Diversity Inversely Correlates with Pathogen-Specific Antibody Levels in Human Cytomegalovirus Infection

(2012) G. C. Wang et al.   Science Translational Medicine

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

(2012) Soi Law et al.   ARTHRITIS RESEARCH & THERAPY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Identification and functional characterization of T cells reactive to citrullinated vimentin in HLA-DRB1*0401-positive humanized mice and rheumatoid arthritis patients

(2011) Omri Snir et al.   ARTHRITIS AND RHEUMATISM

The antigen specificity of the rheumatoid arthritis-associated ACPA directed to citrullinated fibrin is very closely restricted

(2011) Cristina Iobagiu et al.   JOURNAL OF AUTOIMMUNITY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

(2010) Nicole L. La Gruta et al.   JOURNAL OF CLINICAL INVESTIGATION

Paired analysis of TCRα and TCRβ chains at the single-cell level in mice

(2010) Pradyot Dash et al.   JOURNAL OF CLINICAL INVESTIGATION

Mass spectrometric analysis of rheumatoid arthritic synovial tissue identifies specific citrullination sites on fibrinogen

(2010) Monika Hermansson et al.   Proteomics Clinical Applications

Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors

(2009) Daniel G. Pellicci et al.   IMMUNITY

Post-translationally modified T cell epitopes: immune recognition and immunotherapy

(2009) Jan Petersen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Immunity to Citrullinated Proteins in Rheumatoid Arthritis

(2008) Lars Klareskog et al.   Annual Review of Immunology

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice

(2008) Jonathan A. Hill et al.   JOURNAL OF EXPERIMENTAL MEDICINE