Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis

Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint

(2018) Jennifer Pieper et al.   JOURNAL OF AUTOIMMUNITY

Flow Cytometric Clinical Immunomonitoring Using Peptide–MHC Class II Tetramers: Optimization of Methods and Protocol Development

(2018) Diahann T. S. L. Jansen et al.   Frontiers in Immunology

Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells

(2018) Gabriele Blahnik et al.   CELLULAR IMMUNOLOGY

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

(2017) Deepak A. Rao et al.   NATURE

Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining

(2016) Hannes Uchtenhagen et al.   Nature Communications

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis

(2016) Christina Gerstner et al.   Frontiers in Immunology

Chronically Inflamed Human Tissues Are Infiltrated by Highly Differentiated Th17 Lymphocytes

(2014) J. Pene et al.   JOURNAL OF IMMUNOLOGY

Tofacitinib versus Methotrexate in Rheumatoid Arthritis

(2014) Eun Bong Lee et al.   NEW ENGLAND JOURNAL OF MEDICINE

Citrulline-Specific Th1 Cells Are Increased in Rheumatoid Arthritis and Their Frequency Is Influenced by Disease Duration and Therapy

(2014) Eddie A. James et al.   Arthritis & Rheumatology

Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins

(2013) Aase Haj Hensvold et al.   ANNALS OF THE RHEUMATIC DISEASES

Multiplex Analyses of Antibodies Against Citrullinated Peptides in Individuals Prior to Development of Rheumatoid Arthritis

(2013) Mikael Brink et al.   ARTHRITIS AND RHEUMATISM

Structural Changes and Antibody Enrichment in the Lungs Are Early Features of Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis

(2013) Gudrun Reynisdottir et al.   Arthritis & Rheumatology

Hunting for the pathogenesis of rheumatoid arthritis: core-needle biopsy of inguinal lymph nodes as a new research tool

(2012) Maria J H de Hair et al.   ANNALS OF THE RHEUMATIC DISEASES

Autoantigen-specific memory CD4+ T cells are prevalent early in progression to Type 1 diabetes

(2012) Viveka Öling et al.   CELLULAR IMMUNOLOGY

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

(2012) Soi Law et al.   ARTHRITIS RESEARCH & THERAPY

Identification and functional characterization of T cells reactive to citrullinated vimentin in HLA-DRB1*0401-positive humanized mice and rheumatoid arthritis patients

(2011) Omri Snir et al.   ARTHRITIS AND RHEUMATISM

Association of the HLA-DRB1 epitope LA67, 74 with rheumatoid arthritis and citrullinated vimentin binding

(2011) Brian M. Freed et al.   ARTHRITIS AND RHEUMATISM

Genetics of the HLA Region in the Prediction of Type 1 Diabetes

(2011) Janelle A. Noble et al.   Current Diabetes Reports

Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy

(2011) Erik Wambre et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage

(2011) J. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct ex vivo analysis of allergen-specific CD4+ T cells

(2010) William W. Kwok et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Assessment of Seasonal Influenza A Virus-Specific CD4 T-Cell Responses to 2009 Pandemic H1N1 Swine-Origin Influenza A Virus

(2010) X. Ge et al.   JOURNAL OF VIROLOGY

Golimumab, a human anti-tumor necrosis factor α monoclonal antibody, injected subcutaneously every four weeks in methotrexate-naive patients with active rheumatoid arthritis: Twenty-four-week results of a phase III, multicenter, randomized, double-blind, placebo-controlled study of golimumab before methotrexate as first-line therapy for early-onset rheumatoid arthritis

(2009) Paul Emery et al.   ARTHRITIS AND RHEUMATISM

Response of Th17 cells to a citrullinated arthritogenic aggrecan peptide in patients with rheumatoid arthritis

(2009) Alexei von Delwig et al.   ARTHRITIS AND RHEUMATISM

Follicular Helper T Cells: Lineage and Location

(2009) Nicolas Fazilleau et al.   IMMUNITY

Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis

(2009) Natalia Wegner et al.   IMMUNOLOGICAL REVIEWS

Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: Findings of a fifty-two-week, phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study

(2008) Edward Keystone et al.   ARTHRITIS AND RHEUMATISM

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial

(2008) Josef S Smolen et al.   LANCET

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET