Article
Horticulture
Leani Martinez Garcia, Costanza Ceccanti, Carmine Negro, Luigi De Bellis, Luca Incrocci, Alberto Pardossi, Lucia Guidi
Summary: The study found that heat pump drying (HPD) is the best method for processing stinging nettle leaves, resulting in more than a doubling of total phenols and antioxidant activity in the extract.
Article
Chemistry, Multidisciplinary
Purificacion Garcia-Segovia, Marta Igual, Javier Martinez-Monzo
Summary: The study found that adding 7% pea protein during spray drying of beetroot juice resulted in higher spray drying efficiency and better characteristics of the powdered product. The beetroot powder with 7% pea protein was more porous, luminous, and less hygroscopic compared to the one with 3.5% pea protein. However, the higher percentage of pea protein increased water immobilization and reduced soluble solids in the product.
APPLIED SCIENCES-BASEL
(2021)
Review
Biochemistry & Molecular Biology
Umme Tamanna Ferdous, Zetty Norhana Balia Yusof
Summary: Flavonoids, important plant chemicals, are found not only in terrestrial plants but also in microalgae and seaweeds, offering potential for novel anticancer compounds with unique chemical structures and bioactivities. Flavonoids act as antioxidants and have the ability to induce apoptosis and autophagy in cancer cells. However, research on the anticancer properties of flavonoids is mainly focused on terrestrial plants.
Article
Food Science & Technology
Nizam Mustafa Nizamlioglu, Sulhattin Yasar, Yasemin Bulut
Summary: This study investigated the effects of convective and sun drying on quality parameters of apple, plum, and a blend of apple and plum leathers. The study also compared physical, sensory, and chemical attributes determined by chemical methods with an infrared spectroscopic method. Overall, infrared spectroscopic method was recommended for a robust and fast determination of physico-chemical attributes in fruit leather production.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Soniya Amini, Abbas Hassani, Abolfazl Alirezalu, Ramin Maleki
Summary: The study revealed significant variations in TFC, antioxidant activity, TCC, and beta-carotene content among different mullein species. Verbascum saccatum and V. songaricum were found to be particularly rich in total flavonoids and exhibited the highest antioxidant capacity. The results provide valuable information for breeding strategies and selecting the best species with high phenolic compound content for producing natural antioxidants for medical and pharmaceutical use.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Chemistry, Multidisciplinary
Aleksandra Sentkowska, Krystyna Pyrzynska
Summary: This study evaluated the stability of selenium compounds in beetroot juice after the addition of recommended thiols. The concentrations of different selenium species in the juice changed during storage at different temperatures, and the addition of thiols did not have the expected effect. Furthermore, organic beetroot juice showed higher antioxidant activity when stored at low temperature.
APPLIED SCIENCES-BASEL
(2022)
Review
Chemistry, Applied
Nan Shen, Tongfei Wang, Quan Gan, Sian Liu, Li Wang, Biao Jin
Summary: Flavonoids are natural polyphenol substances abundant in various plant-based foods. They have significant biological activities in both plants and humans, such as antioxidant, antimicrobial, and anti-inflammatory effects. However, research on their distribution, biosynthesis, and health benefits remains limited. Future opportunities in flavonoid research include biotechnology, therapeutic phytoproducts, and exploring dietary flavonoid bioavailability.
Article
Biochemistry & Molecular Biology
Neha Kukreti, Havagiray R. Chitme, Vinay K. Varshney, Basel A. Abdel-Wahab, Masood Medleri Khateeb, Mohammed Shafiuddin Habeeb
Summary: This study examined the antioxidant activities of Skimmia anquetilia using in vitro and in vivo models. The plant was found to contain multiple important active constituents with strong antioxidant, hepatoprotective, and nephroprotective activities. Further research on specific active constituents is recommended.
Article
Chemistry, Multidisciplinary
Elif Ayse Anli
Summary: This study investigates the production of Kurut using vacuum-oven drying and oven drying techniques at different temperatures. The results show that vacuum-oven drying can better preserve the quality of Kurut and reduce the drying time.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Applied
Eunsu Song, Jaeyoung Choi, Hyeeun Gwon, Kyo-Yeon Lee, Sung-Gil Choi, Md Atiqual Islam, Jiyeon Chun, Jinah Hwang
Summary: The bioactive compounds and antioxidant activity of different extracts of Dracocephalum moldavica seed were analyzed. The ethanol extract had the highest content of total phenols and flavonoids, as well as the highest radical scavenging activity.
Article
Pharmacology & Pharmacy
Sin Yee Lee, Vincent Ferdinand, Lee Fong Siow
Summary: This study aimed to investigate the effect of drying methods on the properties of chamomile extract powder. The findings showed that convection oven-drying resulted in the highest yield and desirable powder properties, while spray-drying had lower yield and higher moisture content and water activity. Freeze-drying had slightly lower total polyphenol content compared to the other two methods.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Agricultural Engineering
Na Miao, Cholil Yun, Yutong Shi, Yuan Gao, Shuang Wu, Zhonghua Zhang, Shulan Han, Huimei Wang, Wenjie Wang
Summary: This study demonstrates that UV-A radiation can effectively increase the flavonoid content in the aerial parts of Scutellaria baicalensis and enhance its antioxidant activity.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Horticulture
Misun Kim, Seok Kyu Yun, Sang Suk Kim, YoSup Park, Jaeho Joa, Seunggab Han
Summary: Research has shown that freezing at low temperatures affects the cold tolerance, fruit characteristics, amino acid content, volatile compounds, and antioxidant activity of Shiranuhi mandarin, especially with -7 degrees Celsius treatment causing more damage to leaves. Low-temperature treatments reduce the total soluble solid content of the fruit, change its color and firmness, and impact the levels of sugars and organic acids. Furthermore, low-temperature treatments increase amino acid content associated with bitterness in the fruit.
SCIENTIA HORTICULTURAE
(2021)
Article
Biochemistry & Molecular Biology
Samet Kaya Dursun, Burcu Aksut, Osman Nuri Ocalan, Muhammed Tasova
Summary: In this study, different temperatures and methods were compared for drying plant nodes and their effects on color values and quality. The results showed that drying in a 40°C oven can achieve color values closest to fresh grass. The effective diffusion values ranged from 8.85x10(-8) to 5.65x10(-6) m(2) s(-1) in the oven. Rating: 7 out of 10.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Nutrition & Dietetics
Tshamisane Mkhari, Tafadzwa Kaseke, Olaniyi Amos Fawole
Summary: This study evaluated the potential of using maltodextrin, gum Arabic, and their blends to produce functional beetroot waste extract powder. The results showed that using maltodextrin or gum Arabic separately produced powders with better color, solubility, and encapsulation efficiency, and higher levels of bioactive compounds. Blending the two biopolymers improved certain properties but also resulted in agglomeration of the powders.
FRONTIERS IN NUTRITION
(2023)
Article
Multidisciplinary Sciences
Iftekhar Hassan, Rais Ahmad Khan, Jameel Al-Tamimi, Hossam Ebaid, Fohad Mabood Husain, Ibrahim M. Alhazza
Summary: This study aims to evaluate the comparative ameliorative potential of ternary Cu and Zn-based complexes in ceasing CCl4-induced hepatotoxic insults. Results showed significant improvement in most parameters with the Cu (II) complex. Thus, the Cu (II) complex has more substantial ameliorative potential in preventing CCl4-induced hepatotoxicity.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Nutrition & Dietetics
Manal Abdulaziz Binobead, Azhar Hamad Aldakhilallah, Sahar Abdulaziz Alsedairy, Laila Naif Al-Harbi, Wahidah H. Al-Qahtani, Ghedeir M. Alshammari
Summary: This study investigated the effects of a ketogenic diet on anthropometric indices, lipid profile, and the inhibition of NLRP3 inflammasome in obese women. The results showed that the ketogenic diet led to significant weight loss, reduced waist circumference and BHB levels, and decreased BMI and appetite. Cholesterol, triglycerides, and HDL-C slightly increased, while LDL-C and 1L-1 beta decreased significantly. The questionnaire results indicated improvements in various physical symptoms.
Article
Biochemistry & Molecular Biology
Mohammed J. Hakeem, Javed Masood Khan, Ajamaluddin Malik, Fohad Mabood Husain, Sundus Mohammed Alresaini, Aqeel Ahmad, Prawez Alam
Summary: The synthetic food additive dye-induced amyloid fibrillation has various applications in the laboratory and industries. This study investigated the effect of Allura red (AR) on the fibrillation of ovalbumin (Ova) at pH 2.0. The influence of salt and pH on AR-induced Ova aggregation was also examined. Spectroscopic and microscopy techniques were used to characterize the changes. The results showed that AR induced aggregation at concentrations above 0.05 mM, and the size of aggregates increased with AR concentration. The aggregates induced by AR were confirmed to be amyloid-like aggregates. Salt had minimal effects on AR-induced aggregation. The findings emphasize the importance of addressing amyloid fibrillation induced by AR dye in protein for food safety purposes.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Green & Sustainable Science & Technology
Tawaf Ali Shah, Sabiha Khalid, Hiba-Allah Nafidi, Ahmad Mohammad Salamatullah, Mohammed Bourhia
Summary: The study aims to enhance the economic efficiency of producing biomethane from rice straw by pretreating it with NaOH and recycling the solution. The results show that 5% NaOH treatment can remove 73.6% of lignin from the rice straw, and the recycled NaOH solution further reduces the lignin content by 55.5%. After 30 days of incubation, the methane output from the NaOH-treated rice straw is increased by 6-8 times, and the biogas yield is improved by 80-124%. Furthermore, recycling the NaOH solution reduces chemical consumption, decreases water usage, and has the potential to achieve optimum methane yield in anaerobic digestion.
Article
Neurosciences
Mohd Imran Khan, Park Taehwan, Yunseong Cho, Marcus Scotti, Renata Priscila Barros de Menezes, Fohad Mabood Husain, Suliman Yousef Alomar, Mohammad Hassan Baig, Jae-June Dong
Summary: Alzheimer's disease (AD) is a progressive neurodegenerative disorder affecting a large population worldwide. This study used machine learning modeling to search for potential drug candidates that inhibit acetylcholinesterase, providing a new approach for the treatment of AD.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Samiyah K. Al-Shammari, Doha M. Al-Nouri, Shaista Arzoo, Laila Naif Al-Harbi
Summary: This study evaluated the protective effect of different dietary omega-6/omega-3 ratios in oils obtained from various nuts against morphological features and markers of inflammation on an adjuvant-induced arthritis rat model. The results showed that the serum levels of inflammatory markers were significantly reduced in all treatment groups.
APPLIED SCIENCES-BASEL
(2023)
Article
Food Science & Technology
Kashif Ghafoor, Md. Zaidul Islam Sarker, Fahad Y. Al-Juhaimi, Isam A. Mohamed Ahmed, Elfadil E. Babiker, Mohammed S. Alkaltham, Abdullah K. Almubarak
Summary: The bioactive compounds of four Saudi date flesh extracts were evaluated using different extraction methods. Both the date variety and extraction method affected the phenolic profile of the extracts. The incorporation of date flesh extracts into yogurt increased the total phenolic content, antiradical activity, viscosity, and redness of the product.
Article
Multidisciplinary Sciences
Mohammed Asif Ahmed, Abdulrahman S. Al-Khalifa, Doha M. Al-Nouri, Mohamed Fekry Serag El-din
Summary: This study aimed to determine the daily intake of ten types of artificial food color additives (AFCAs) by school children aged 6 to 17 years. Results showed that Carmoisine and Sunset Yellow were the most consumed AFCAs, while Erythrosine was consumed the least. Most permitted colors exceeded their acceptable daily intakes in the 6-11 years of age groups. Further studies are needed to understand the potential health effects of high intake of AFCAs in the test population.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Manal M. Alkhulaifi, Malak M. Alosaimi, Mohd Shahnawaz Khan, Shams Tabrez, Gouse M. Shaik, Majed S. Alokail, Mohammed A. Hassan, Muawiya E. Awadalla, Fohad Mabood Husain
Summary: Lactoferrin was purified from camel milk colostrum using cation exchange chromatography and its antimicrobial potential was assessed. The purified lactoferrin showed inhibitory effects against methicillin-resistant S. aureus, S. aureus, K. pneumonia, and multidrug-resistant P. aeruginosa. The iron-free lactoferrin and hydrolyzed lactoferrin were more effective against MRSA. Scanning electron microscopy analysis revealed distortions in bacterial cells exposed to lactoferrin. The lactoferrin forms also exhibited antibiofilm activity and dose-dependent cytotoxicity against human lung cancer cells.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Faizan Abul Qais, Iqbal Ahmad, Fohad Mabood Husain, Mohammed Arshad, Altaf Khan, Mohd Adil
Summary: In the past two decades, antimicrobial resistance (AMR) has exponentially increased, posing a serious threat to human health. AMR is a leading cause of mortality worldwide. Despite a successful discovery of new antibiotics in the 20th century, little progress has been made in this area recently. Due to the rise in AMR and the slow progress in antibiotic discovery, there is an urgent need for new intervention methods to combat infectious diseases. One approach is to search for biofilm and quorum sensing inhibitors, and plants are a rich source of compounds that could exhibit these properties.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Anatomy & Morphology
Faizan Abul Qais, Mohammad Shavez Khan, Iqbal Ahmad, Fohad Mabood Husain, Mohammed Arshad, Altaf Khan, Mohd Adil
Summary: The development of antibiotic resistant microbial pathogens has become a global health threat and a major concern in modern medicine. Plants are considered as promising source for new drugs against antimicrobial resistance (AMR) pathogens. In this study, the potential of Cinnamomum zeylanicum extract in targeting the virulence of Gram -ve pathogenic bacteria was demonstrated.
MICROSCOPY RESEARCH AND TECHNIQUE
(2023)
Article
Anatomy & Morphology
Mo Ahamad Khan, Mohammad Shahid, Ismail Celik, Haris M. Khan, Anwar Shahzad, Fohad Mabood Husain, Mohd Adil
Summary: The present study investigated the anti-quorum sensing and biofilm inhibitory activity of Artemisia annua leaf extract (AALE) and its bioactive compound 1, 8-cineole. The results demonstrated that AALE and 1, 8-cineole could inhibit the virulence factors and biofilm formation of bacterial pathogens. The findings suggest the potential of AALE and 1, 8-cineole as therapeutic agents for multidrug-resistant infections.
MICROSCOPY RESEARCH AND TECHNIQUE
(2023)
Article
Microbiology
Margi Patel, Shaikhul Islam, Fohad Mabood Husain, Virendra Kumar Yadav, Hyun-Kyung Park, Krishna Kumar Yadav, Snehal Bagatharia, Madhvi Joshi, Byong-Hun Jeon, Ashish Patel
Summary: This study aimed to uncover multitrait bioinoculants from hostile ecosystems that could help mitigate salinity and drought stresses. The BST isolate demonstrated notable plant growth promoting qualities and suppressed the growth of Fusarium oxysporum. It also functioned well under several abiotic stress conditions, indicating its potential as an effective bio-inoculant.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biology
Hani H. Al-Baadani, Ibrahim A. Alhidary, Abdulrahman S. Alharthi, Mahmoud M. Azzam, Gamaleldin M. Suliman, Mohammed A. Ahmed, Akram A. Qasem
Summary: The effects of PJ on carcass traits and breast meat quality parameters of broiler chickens were investigated. Results showed that PJ improved performance parameters, carcass characteristics, and fatty acid profile, and some meat quality traits were generally improved. However, further investigation is needed to understand its mode of action.
Article
Plant Sciences
Mohd Aamir, V. Shanmugam, Manish Kumar Dubey, Fohad Mabood Husain, Mohd Adil, Waquar Akhter Ansari, Ashutosh Rai, Pankaj Sah
Summary: In this study, the complex interaction between Trichoderma and the tomato genome was investigated, revealing transcriptional and metabolic changes triggered by Trichoderma colonization. Gene expression profile analysis identified differentially expressed significant genes, showing a positive correlation between the host and Trichoderma. Several genes were found to be consistently significant, with some showing upregulated expression and others downregulated expression during Trichoderma-tomato interaction. Transcription factors related to systemic defense and flowering were also differentially expressed. Protein-protein interaction network analysis and Weighted Correlation Gene Network Analysis further revealed the genes associated with carbohydrate metabolism, secondary metabolite biosynthesis, and nitrogen metabolism. Overall, this study highlights the importance of Trichoderma-induced microbial priming in reprogramming the host genome for transcriptional response and understanding the complex regulatory networks in beneficial microbial interactions.