Targeted Therapy With PI3K and FGFR Inhibitors on Human Papillomavirus Positive and Negative Tonsillar and Base of Tongue Cancer Lines With and Without Corresponding Mutations
出版年份 2021 全文链接
标题
Targeted Therapy With PI3K and FGFR Inhibitors on Human Papillomavirus Positive and Negative Tonsillar and Base of Tongue Cancer Lines With and Without Corresponding Mutations
作者
关键词
-
出版物
Frontiers in Oncology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2021-05-11
DOI
10.3389/fonc.2021.640490
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Targeting Fibroblast Growth Factor Receptor (FGFR) and Phosphoinositide 3-kinase (PI3K) Signaling Pathways in Medulloblastoma Cell Lines
- (2020) STEFAN HOLZHAUSER et al. ANTICANCER RESEARCH
- Sensitivity of human papillomavirus‑positive and ‑negative oropharyngeal cancer cell lines to ionizing irradiation
- (2020) Stefan Holzhauser et al. ONCOLOGY REPORTS
- Synergistic antitumor effect of dual PI3K and mTOR inhibitor NVP‑BEZ235 in combination with cisplatin on drug‑resistant non‑small cell lung cancer cell
- (2020) Hao Zhu et al. Oncology Letters
- PIK3CA in cancer: The past 30 years
- (2019) Rand Arafeh et al. SEMINARS IN CANCER BIOLOGY
- Multicenter Phase I Study of Erdafitinib (JNJ-42756493), Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients with Advanced or Refractory Solid Tumors
- (2019) Rastilav Bahleda et al. CLINICAL CANCER RESEARCH
- Alpelisib for PIK3CA-Mutated, Hormone Receptor–Positive Advanced Breast Cancer
- (2019) Fabrice André et al. NEW ENGLAND JOURNAL OF MEDICINE
- Analyses of FGFR3 and PIK3CA mutations in neuroblastomas and the effects of the corresponding inhibitors on neuroblastoma cell lines
- (2019) Ourania Kostopoulou et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- PIK3CA mutation in HPV-associated OPSCC patients receiving deintensified chemoradiation
- (2019) Brian T Beaty et al. JNCI-Journal of the National Cancer Institute
- In�vitro antitumor effects of FGFR and PI3K inhibitors on human papillomavirus positive and negative tonsillar and base of tongue cancer cell lines
- (2019) Stefan Holzhauser et al. Oncology Letters
- A global epidemic increase of an HPV‐induced tonsil and tongue base cancer – potential benefit from a pan‐gender use of HPV vaccine
- (2019) A. Näsman et al. JOURNAL OF INTERNAL MEDICINE
- Future applications of FGF/FGFR inhibitors in cancer
- (2018) Gaia Cristina Ghedini et al. Expert Review of Anticancer Therapy
- Epidemiologic associations of HPV-positive oropharyngeal cancer and (pre)cancerous cervical lesions
- (2018) M.M. Rietbergen et al. INTERNATIONAL JOURNAL OF CANCER
- Novel therapeutic strategy for cervical cancer harboring FGFR3-TACC3 fusions
- (2018) Ryo Tamura et al. Oncogenesis
- Overexpression of FGFR3 in HPV-positive Tonsillar and Base of Tongue Cancer Is Correlated to Outcome
- (2018) CINZIA BERSANI et al. ANTICANCER RESEARCH
- Changes in incidence and prevalence of human papillomavirus in tonsillar and base of tongue cancer during 2000-2016 in the Stockholm region and Sweden
- (2018) Linnea Haeggblom et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Sensitivity to inhibition of DNA repair by Olaparib in novel oropharyngeal cancer cell lines infected with Human Papillomavirus
- (2018) Evelyne F. Pirotte et al. PLoS One
- A Functional Genetic Screen Identifies the Phosphoinositide 3-kinase Pathway as a Determinant of Resistance to Fibroblast Growth Factor Receptor Inhibitors in FGFR Mutant Urothelial Cell Carcinoma
- (2017) Liqin Wang et al. EUROPEAN UROLOGY
- Targeting VEGFR and FGFR in head and neck squamous cell carcinoma in vitro
- (2017) Roman C. Brands et al. ONCOLOGY REPORTS
- A model using concomitant markers for predicting outcome in human papillomavirus positive oropharyngeal cancer
- (2017) Cinzia Bersani et al. ORAL ONCOLOGY
- Distinct patterns of infiltrating CD8+ T cells in HPV+ and CD68 macrophages in HPV- oropharyngeal squamous cell carcinomas are associated with better clinical outcome but PD-L1 expression is not prognostic
- (2017) Kenneth Oguejiofor et al. Oncotarget
- Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3
- (2017) Cinzia Bersani et al. Oncotarget
- Targeted next-generation sequencing of locally advanced squamous cell carcinomas of the head and neck reveals druggable targets for improving adjuvant chemoradiation
- (2016) I. Tinhofer et al. EUROPEAN JOURNAL OF CANCER
- Stromal infiltration of CD8 T cells is associated with improved clinical outcome in HPV-positive oropharyngeal squamous carcinoma
- (2015) K Oguejiofor et al. BRITISH JOURNAL OF CANCER
- Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC
- (2015) K. R. Singleton et al. CANCER RESEARCH
- First-in-Human Phase I Study of GSK2126458, an Oral Pan-Class I Phosphatidylinositol-3-Kinase Inhibitor, in Patients with Advanced Solid Tumor Malignancies
- (2015) P. Munster et al. CLINICAL CANCER RESEARCH
- A model for predicting clinical outcome in patients with human papillomavirus-positive tonsillar and base of tongue cancer
- (2015) Nikolaos Tertipis et al. EUROPEAN JOURNAL OF CANCER
- Reduced Expression of the Antigen Processing Machinery Components TAP2, LMP2, and LMP7 in Tonsillar and Base of Tongue Cancer and Implications for Clinical Outcome
- (2015) Nikolaos Tertipis et al. Translational Oncology
- Fibroblast growth factor receptor 3 protein is overexpressed in oral and oropharyngeal squamous cell carcinoma
- (2015) Koos Koole et al. Cancer Medicine
- Abstract 5522: Anticancer activity of novel PI3K inhibitor BYL719 in head and neck cancer cell lines
- (2015) Bhumsuk Keam et al. CANCER RESEARCH
- Expression of LRIG1 is associated with good prognosis and human papillomavirus status in oropharyngeal cancer
- (2014) D Lindquist et al. BRITISH JOURNAL OF CANCER
- A high and increasing HPV prevalence in tonsillar cancers in Eastern Denmark, 2000-2010: The largest registry-based study to date
- (2014) Emilie Garnaes et al. INTERNATIONAL JOURNAL OF CANCER
- Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells
- (2014) J Wang et al. ONCOGENE
- Epidemiology of HPV-associated oropharyngeal cancer
- (2014) Kristen B. Pytynia et al. ORAL ONCOLOGY
- Correlation of LMP10 Expression and Clinical Outcome in Human Papillomavirus (HPV) Positive and HPV-Negative Tonsillar and Base of Tongue Cancer
- (2014) Nikolaos Tertipis et al. PLoS One
- Preclinical evaluation of the mTOR–PI3K inhibitor BEZ235 in nasopharyngeal cancer models
- (2013) Brigette B.Y. Ma et al. CANCER LETTERS
- CD8+ and CD4+ tumour infiltrating lymphocytes in relation to human papillomavirus status and clinical outcome in tonsillar and base of tongue squamous cell carcinoma
- (2013) Cecilia Nordfors et al. EUROPEAN JOURNAL OF CANCER
- Cancer stem cell enrichment marker CD98: A prognostic factor for survival in patients with human papillomavirus-positive oropharyngeal cancer
- (2013) Michelle M. Rietbergen et al. EUROPEAN JOURNAL OF CANCER
- HLA Class I and II Expression in Oropharyngeal Squamous Cell Carcinoma in Relation to Tumor HPV Status and Clinical Outcome
- (2013) Anders Näsman et al. PLoS One
- Parallel RNA Interference Screens Identify EGFR Activation as an Escape Mechanism in FGFR3-Mutant Cancer
- (2013) M. T. Herrera-Abreu et al. Cancer Discovery
- Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors
- (2013) Matthias Lechner et al. Genome Medicine
- Absent/weak CD44 intensity and positive human papillomavirus (HPV) status in oropharyngeal squamous cell carcinoma indicates a very high survival
- (2013) Anders Näsman et al. Cancer Medicine
- MHC class I expression in HPV positive and negative tonsillar squamous cell carcinoma in correlation to clinical outcome
- (2012) Anders Näsman et al. INTERNATIONAL JOURNAL OF CANCER
- Tumor Infiltrating CD8+ and Foxp3+ Lymphocytes Correlate to Clinical Outcome and Human Papillomavirus (HPV) Status in Tonsillar Cancer
- (2012) Anders Näsman et al. PLoS One
- Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States
- (2011) Anil K. Chaturvedi et al. JOURNAL OF CLINICAL ONCOLOGY
- Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer
- (2010) K. Kian Ang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Toll-like receptors in tonsillar epithelial cells
- (2009) Margaret J. Lange et al. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
- Effect of HPV-Associated p16INK4A Expression on Response to Radiotherapy and Survival in Squamous Cell Carcinoma of the Head and Neck
- (2009) Pernille Lassen et al. JOURNAL OF CLINICAL ONCOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now