Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors

Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma

(2013) Matthias Lechner et al.   Genome Medicine

An integrated view of cyclin E function and regulation

(2012) Ka Tat Siu et al.   CELL CYCLE

mTOR as a Molecular Target in HPV-Associated Oral and Cervical Squamous Carcinomas

(2012) A. A. Molinolo et al.   CLINICAL CANCER RESEARCH

mTOR Inhibitors and its Role in the Treatment of Head and Neck Squamous Cell Carcinoma

(2012) Shaun A. Nguyen et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing

(2012) Bojana Djordjevic et al.   MODERN PATHOLOGY

Absolute quantification of somatic DNA alterations in human cancer

(2012) Scott L Carter et al.   NATURE BIOTECHNOLOGY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Evaluation of Human Papilloma Virus Diagnostic Testing in Oropharyngeal Squamous Cell Carcinoma: Sensitivity, Specificity, and Prognostic Discrimination

(2011) A. G. Schache et al.   CLINICAL CANCER RESEARCH

Prognostic significance of cyclinD1 amplification and the co-alteration of cyclinD1/pRb/ppRb in patients with esophageal squamous cell carcinoma

(2011) M.-T. Wang et al.   DISEASES OF THE ESOPHAGUS

PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity

(2011) Christina Schülein et al.   FEBS LETTERS

Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States

(2011) Anil K. Chaturvedi et al.   JOURNAL OF CLINICAL ONCOLOGY

Smoking history and lung carcinoma: KRAS mutation is an early hit in lung adenocarcinoma development

(2011) F.B. Thunnissen et al.   LUNG CANCER

How to apply de Bruijn graphs to genome assembly

(2011) Phillip E C Compeau et al.   NATURE BIOTECHNOLOGY

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Evidence for Epithelial-Mesenchymal Transition in Cancer Stem Cells of Head and Neck Squamous Cell Carcinoma

(2011) Chao Chen et al.   PLoS One

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

(2011) N. Agrawal et al.   SCIENCE

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

Progressive 3q Amplification Consistently TargetsSOX2in Preinvasive Squamous Lung Cancer

(2010) Frank McCaughan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes

(2010) Debora Fumagalli et al.   BMC CANCER

SOX2 identified as a target gene for the amplification at 3q26 that is frequently detected in esophageal squamous cell carcinoma

(2010) Yasuyuki Gen et al.   CANCER GENETICS AND CYTOGENETICS

Comprehensive Mapping of p53 Pathway Alterations Reveals an Apparent Role for Both SNP309 and MDM2 Amplification in Sarcomagenesis

(2010) M. Ito et al.   CLINICAL CANCER RESEARCH

Localization-specific LKB1 loss in head and neck squamous cell carcinoma metastasis

(2010) Erik R. Kline et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL–BFM 2000 protocol can be separated from FBXW7 loss of function

(2010) C Kox et al.   LEUKEMIA

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Allele-specific copy number analysis of tumors

(2010) P. Van Loo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Papillomavirus and Head and Neck Cancer

(2009) William M. Mendenhall et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Human Papillomavirus and Oropharyngeal Cancer: What You Need to Know in 2009

(2009) M. Boyd Gillespie et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Recurrent copy number gain of transcription factorSOX2and corresponding high protein expression in oral squamous cell carcinoma

(2009) Kolja Freier et al.   GENES CHROMOSOMES & CANCER

Improved Survival of Patients With Human Papillomavirus-Positive Head and Neck Squamous Cell Carcinoma in a Prospective Clinical Trial

(2008) C. Fakhry et al.   JNCI-Journal of the National Cancer Institute