A Tale of Ice and Fire: The Dual Role for 17β-Estradiol in Balancing DNA Damage and Genome Integrity
出版年份 2021 全文链接
标题
A Tale of Ice and Fire: The Dual Role for 17β-Estradiol in Balancing DNA Damage and Genome Integrity
作者
关键词
-
出版物
Cancers
Volume 13, Issue 7, Pages 1583
出版商
MDPI AG
发表日期
2021-03-30
DOI
10.3390/cancers13071583
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Real‐time measurement of E2: ERα transcriptional activity in living cells
- (2020) Manuela Cipolletti et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Targeting DNA-PK in cancer
- (2020) Giovanna Damia MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- DNA damage repair functions and targeted treatment in breast cancer
- (2020) Chenfeng He et al. Breast Cancer
- The tissue-specific effects of different 17β-estradiol doses reveal the key sensitizing role of AF1 domain in ERα activity
- (2020) Coralie Fontaine et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Sirt3 Exerts Its Tumor-Suppressive Role by Increasing p53 and Attenuating Response to Estrogen in MCF-7 Cells
- (2020) Marija Pinterić et al. Antioxidants
- Global View of Candidate Therapeutic Target Genes in Hormone-Responsive Breast Cancer
- (2020) Annamaria Salvati et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Yeast ATM and ATR kinases use different mechanisms to spread histone H2A phosphorylation around a DNA double-strand break
- (2020) Kevin Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of Antiestrogen‐Bound Estrogen Receptor α Interactomes in Hormone‐Responsive Human Breast Cancer Cell Nuclei
- (2020) Valerio Gigantino et al. PROTEOMICS
- Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner
- (2019) Julien N. Bianco et al. Nature Communications
- Estrogen down regulates COMT transcription via promoter DNA methylation in human breast cancer cells
- (2019) Qian Wu et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
- (2019) Fiona M. Behan et al. NATURE
- Quantitative mechanisms of DNA damage sensing and signaling
- (2019) Susanne C. S. Bantele et al. CURRENT GENETICS
- Mixed ubiquitin chains regulate DNA repair
- (2019) Gergely Rona et al. GENES & DEVELOPMENT
- Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA
- (2019) Morimoto et al. Genes
- SUMOylation homeostasis in tumorigenesis
- (2019) Minyue Xie et al. CANCER LETTERS
- NBS1 interacts with HP1 to ensure genome integrity
- (2019) Giuseppe Bosso et al. Cell Death & Disease
- Claspin - checkpoint adaptor and DNA replication factor
- (2018) Veronique A. J. Smits et al. FEBS Journal
- Timeless Is a Novel Estrogen Receptor Co-activator Involved in Multiple Signaling Pathways in MCF-7 Cells
- (2018) Chantal Beatrice Magne Nde et al. JOURNAL OF MOLECULAR BIOLOGY
- Histone modifications and the DNA double-strand break response
- (2018) Hieu T. Van et al. CELL CYCLE
- BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II–DNA complexes
- (2018) Hiroyuki Sasanuma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons
- (2017) Pierre Billon et al. MOLECULAR CELL
- Poly-ADP ribosylation in DNA damage response and cancer therapy
- (2017) Wei-Hsien Hou et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- The essential kinase ATR: ensuring faithful duplication of a challenging genome
- (2017) Joshua C. Saldivar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA replication stress: from molecular mechanisms to human disease
- (2016) Sergio Muñoz et al. CHROMOSOMA
- Dynamin II is required for 17β-estradiol signaling and autophagy-based ERα degradation
- (2016) Pierangela Totta et al. Scientific Reports
- Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage
- (2016) Caroline Townsend Stork et al. eLife
- Mechanisms of ATM Activation
- (2015) Tanya T. Paull Annual Review of Biochemistry
- DNA Replication Stress as a Hallmark of Cancer
- (2015) Morgane Macheret et al. Annual Review of Pathology-Mechanisms of Disease
- Structure of a Biologically Active Estrogen Receptor-Coactivator Complex on DNA
- (2015) Ping Yi et al. MOLECULAR CELL
- TIPIN depletion leads to apoptosis in breast cancer cells
- (2015) Céline Baldeyron et al. Molecular Oncology
- The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis
- (2015) Nicholas Jette et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Mechanisms of estrogen carcinogenesis: The role of E2/E1–quinone metabolites suggests new approaches to preventive intervention – A review
- (2015) James D. Yager STEROIDS
- 17β-estradiol prevents experimentally-induced oxidative damage to membrane lipids and nuclear DNA in porcine ovary
- (2015) Jan Stepniak et al. Systems Biology in Reproductive Medicine
- BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability
- (2014) K. I. Savage et al. CANCER RESEARCH
- Enhancer Activation Requires trans-Recruitment of a Mega Transcription Factor Complex
- (2014) Zhijie Liu et al. CELL
- Membrane-Localized Estrogen Receptor α Is Required for Normal Organ Development and Function
- (2014) Ali Pedram et al. DEVELOPMENTAL CELL
- Estrogen Signaling and the DNA Damage Response in Hormone Dependent Breast Cancers
- (2014) C. Elizabeth Caldon Frontiers in Oncology
- Potential cancer-related role of circadian gene TIMELESS suggested by expression profiling and in vitro analyses
- (2013) Yingying Mao et al. BMC CANCER
- Estrogen Receptor Regulates ATM Expression through miRNAs in Breast Cancer
- (2013) X. Guo et al. CLINICAL CANCER RESEARCH
- Causes and consequences of replication stress
- (2013) Michelle K. Zeman et al. NATURE CELL BIOLOGY
- The ATM protein kinase: regulating the cellular response to genotoxic stress and more
- (2013) Yosef Shiloh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mutation of the palmitoylation site of estrogen receptor in vivo reveals tissue-specific roles for membrane versus nuclear actions
- (2013) M. Adlanmerini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases
- (2013) W.-H. Cho et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA Damage Sensing by the ATM and ATR Kinases
- (2013) A. Marechal et al. Cold Spring Harbor Perspectives in Biology
- DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis
- (2012) Wynand P. Roos et al. CANCER LETTERS
- R-Loop Formation Is a Distinctive Characteristic of Unmethylated Human CpG Island Promoters
- (2012) Paul A. Ginno et al. MOLECULAR CELL
- Palmitoylation Regulates 17β-Estradiol-Induced Estrogen Receptor-α Degradation and Transcriptional Activity
- (2012) Piergiorgio La Rosa et al. MOLECULAR ENDOCRINOLOGY
- Thresholds of replication stress signaling in cancer development and treatment
- (2012) Jiri Bartek et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Analysis of multiplex endogenous estrogen metabolites in human urine using ultra-fast liquid chromatography–tandem mass spectrometry: A case study for breast cancer
- (2011) Jiang Huang et al. ANALYTICA CHIMICA ACTA
- Endocrine Therapy of Breast Cancer
- (2011) F. Lumachi et al. CURRENT MEDICINAL CHEMISTRY
- Soy Isoflavones, CYP1A1, CYP1B1, and COMT Polymorphisms, and Breast Cancer: A Case–Control Study in Southwestern China
- (2011) Qiong Wang et al. DNA AND CELL BIOLOGY
- Cracking the Estrogen Receptor's Posttranslational Code in Breast Tumors
- (2011) Muriel Le Romancer et al. ENDOCRINE REVIEWS
- Sex Hormone Levels and Risks of Estrogen Receptor-Negative and Estrogen Receptor-Positive Breast Cancers
- (2011) G. N. Farhat et al. JNCI-Journal of the National Cancer Institute
- Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination
- (2011) Konstantina Skourti-Stathaki et al. MOLECULAR CELL
- Targeting ATR and Chk1 kinases for cancer treatment: A new model for new (and old) drugs
- (2011) Luis I. Toledo et al. Molecular Oncology
- Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors
- (2011) Matilde Murga et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- miR-18a Impairs DNA Damage Response through Downregulation of Ataxia Telangiectasia Mutated (ATM) Kinase
- (2011) Libing Song et al. PLoS One
- The Effects of 17β-estradiol in Cancer are Mediated by Estrogen Receptor Signaling at the Plasma Membrane
- (2011) Filippo Acconcia et al. Frontiers in Physiology
- Estrogen receptor α-mediated transcription induces cell cycle-dependent DNA double-strand breaks
- (2010) Laura M. Williamson et al. CARCINOGENESIS
- Estrogen Receptors: Therapies Targeted to Receptor Subtypes
- (2010) S Nilsson et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The ATR barrier to replication-born DNA damage
- (2010) Andrés J. López-Contreras et al. DNA REPAIR
- Transcriptional activation of DNA-dependent protein kinase catalytic subunit gene expression by oestrogen receptor-α
- (2010) Senad Medunjanin et al. EMBO REPORTS
- Interaction of the Double-Strand Break Repair Kinase DNA-PK and Estrogen Receptor-α
- (2010) Senad Medunjanin et al. MOLECULAR BIOLOGY OF THE CELL
- Comparative analysis of nuclear estrogen receptor alpha and beta interactomes in breast cancer cells
- (2010) Giovanni Nassa et al. Molecular BioSystems
- Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
- (2010) Michael C Haffner et al. NATURE GENETICS
- Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS
- (2010) Roberta Tarallo et al. PROTEOMICS
- Estrogen Inhibits ATR Signaling to Cell Cycle Checkpoints and DNA Repair
- (2009) Ali Pedram et al. MOLECULAR BIOLOGY OF THE CELL
- Resveratrol Prevents Estrogen-DNA Adduct Formation and Neoplastic Transformation in MCF-10F Cells
- (2008) F. Lu et al. Cancer Prevention Research
- Prevention of estrogen–DNA adduct formation in MCF-10F cells by resveratrol
- (2008) Muhammad Zahid et al. FREE RADICAL BIOLOGY AND MEDICINE
- ATR signaling can drive cells into senescence in the absence of DNA breaks
- (2008) L. I. Toledo et al. GENES & DEVELOPMENT
- An Oncogene-Induced DNA Damage Model for Cancer Development
- (2008) T. D. Halazonetis et al. SCIENCE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started