Presence of Bromotyrosine Alkaloids in Marine Sponges Is Independent of Metabolomic and Microbiome Architectures

Multi-Omic Profiling of Melophlus Sponges Reveals Diverse Metabolomic and Microbiome Architectures that Are Non-overlapping with Ecological Neighbors

(2020) Ipsita Mohanty et al.   Marine Drugs

Precursor-Guided Mining of Marine Sponge Metabolomes Lends Insight into Biosynthesis of Pyrrole–Imidazole Alkaloids

(2020) Ipsita Mohanty et al.   ACS Chemical Biology

Hawaiian Bobtail Squid Symbionts Inhibit Marine Bacteria via Production of Specialized Metabolites, Including New Bromoalterochromides BAC-D/D′

(2020) Andrea M. Suria et al.   mSphere

Opisthobranch grazing results in mobilisation of spherulous cells and re-allocation of secondary metabolites in the sponge Aplysina aerophoba

(2020) Yu-Chen Wu et al.   Scientific Reports

Metabolomics and Marine Biotechnology: Coupling Metabolite Profiling and Organism Biology for the Discovery of New Compounds

(2020) Miriam Reverter et al.   Frontiers in Marine Science

Chemical Ecology of Marine Sponges: New Opportunities through “-Omics”

(2019) Valerie J Paul et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Mass Spectrometry-Based Integration and Expansion of the Chemical Diversity Harbored Within a Marine Sponge

(2019) Thomas P. Cantrell et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Revisiting Fragmentation Reactions of Protonated α-Amino Acids by High-Resolution Electrospray Ionization Tandem Mass Spectrometry with Collision-Induced Dissociation

(2019) Pengwei Zhang et al.   Scientific Reports

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

(2019) Evan Bolyen et al.   NATURE BIOTECHNOLOGY

Parallel lives of symbionts and hosts: chemical mutualism in marine animals

(2018) Maho Morita et al.   NATURAL PRODUCT REPORTS

Chemical encoding of risk perception and predator detection among estuarine invertebrates

(2018) Remington X. Poulin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis and trypanocide activity of chloro-l-tyrosine and bromo-l-tyrosine derivatives

(2018) Manuel Pastrana Restrepo et al.   MEDICINAL CHEMISTRY RESEARCH

Marine Sponges as Chloroflexi Hot Spots: Genomic Insights and High-Resolution Visualization of an Abundant and Diverse Symbiotic Clade

(2018) Kristina Bayer et al.   mSystems

Determination of the Halogenated Skeleton Constituents of the Marine Demosponge Ianthella basta

(2017) Susanne Ueberlein et al.   Marine Drugs

Predicting the HMA-LMA Status in Marine Sponges by Machine Learning

(2017) Lucas Moitinho-Silva et al.   Frontiers in Microbiology

Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP)

(2016) Sudha Korwar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

DADA2: High-resolution sample inference from Illumina amplicon data

(2016) Benjamin J Callahan et al.   NATURE METHODS

Characterization of AmtA, an amidinotransferase involved in the biosynthesis of phaseolotoxins

(2016) Mi Li et al.   FEBS Open Bio

Cinchona Alkaloid Catalyzed Sulfa-Michael Addition Reactions Leading to Enantiopure β-Functionalized Cysteines

(2015) Arjen C. Breman et al.   JOURNAL OF ORGANIC CHEMISTRY

Protein carbamylation is a hallmark of aging

(2015) Laëtitia Gorisse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyanogenic Glycosides: Synthesis, Physiology, and Phenotypic Plasticity

(2014) Roslyn M. Gleadow et al.   Annual Review of Plant Biology

The chemical logic of plant natural product biosynthesis

(2014) Gülbenk Anarat-Cappillino et al.   CURRENT OPINION IN PLANT BIOLOGY

The Skeletal Amino Acid Composition of the Marine Demosponge Aplysina cavernicola

(2014) Susanne Ueberlein et al.   Marine Drugs

Chemical defenses and resource trade-offs structure sponge communities on Caribbean coral reefs

(2014) T.-L. Loh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted Capture and Heterologous Expression of the Pseudoalteromonas Alterochromide Gene Cluster in Escherichia coli Represents a Promising Natural Product Exploratory Platform

(2014) Avena C. Ross et al.   ACS Synthetic Biology

Meroterpenes from Marine Invertebrates: Structures, Occurrence, and Ecological Implications

(2013) Marialuisa Menna et al.   Marine Drugs

BLAST: a more efficient report with usability improvements

(2013) Grzegorz M. Boratyn et al.   NUCLEIC ACIDS RESEARCH

The SILVA and “All-species Living Tree Project (LTP)” taxonomic frameworks

(2013) Pelin Yilmaz et al.   NUCLEIC ACIDS RESEARCH

EMPeror: a tool for visualizing high-throughput microbial community data

(2013) Yoshiki Vázquez-Baeza et al.   GigaScience

Promiscuous activity of arginine:glycine amidinotransferase is responsible for the synthesis of the novel cardiovascular risk factor homoarginine

(2012) Mariska Davids et al.   FEBS LETTERS

Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets

(2012) Matthias G. J. Baud et al.   JOURNAL OF MEDICINAL CHEMISTRY

Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids

(2011) Ali Al-Mourabit et al.   NATURAL PRODUCT REPORTS

MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data

(2010) Tomáš Pluskal et al.   BMC BIOINFORMATICS

Additional Insights on the Bastadins: Isolation of Analogues from the SpongeIanthellacf.reticulataand Exploration of the Oxime Configurations†

(2010) Laurent Calcul et al.   JOURNAL OF NATURAL PRODUCTS

Marine chemical ecology in benthic environments

(2010) Valerie J. Paul et al.   NATURAL PRODUCT REPORTS

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Activated Chemical Defense in Marine Sponges—a Case Study on Aplysinella rhax

(2008) Carsten Thoms et al.   JOURNAL OF CHEMICAL ECOLOGY

Drug development from marine natural products

(2008) Tadeusz F. Molinski et al.   NATURE REVIEWS DRUG DISCOVERY