Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice
出版年份 2021 全文链接
标题
Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice
作者
关键词
-
出版物
Science Advances
Volume 7, Issue 14, Pages eabb0799
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2021-04-01
DOI
10.1126/sciadv.abb0799
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Endothelial Palmitoylation Cycling Coordinates Vessel Remodeling in Peripheral Artery Disease
- (2020) Xiaochao Wei et al. CIRCULATION RESEARCH
- Huntington’s disease alters human neurodevelopment
- (2020) Monia Barnat et al. SCIENCE
- Dynamic Palmitoylation of the Sodium-Calcium Exchanger Modulates Its Structure, Affinity for Lipid-Ordered Domains, and Inhibition by XIP
- (2020) Caglar Gök et al. Cell Reports
- Upregulation of Cellular Palmitoylation Mitigates α‐Synuclein Accumulation and Neurotoxicity
- (2020) Gary P.H. Ho et al. MOVEMENT DISORDERS
- CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
- (2020) Jian-Wei Hao et al. Nature Communications
- Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network
- (2019) Simona Gribaudo et al. Stem Cell Reports
- Identifying the potential substrates of the depalmitoylation enzyme Acyl-protein thioesterase 1
- (2019) Huicong Liu et al. CURRENT MOLECULAR MEDICINE
- Axonal transport and neurological disease
- (2019) James N. Sleigh et al. Nature Reviews Neurology
- Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington’s Disease
- (2018) Amandine Virlogeux et al. Cell Reports
- High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration
- (2018) Ismael Al-Ramahi et al. Cell Systems
- Neuronal network maturation differently affects secretory vesicles and mitochondria transport in axons
- (2018) Eve Moutaux et al. Scientific Reports
- Integrated genomics and proteomics define huntingtin CAG length–dependent networks in mice
- (2016) Peter Langfelder et al. NATURE NEUROSCIENCE
- Postnatal and adult consequences of loss of huntingtin during development: Implications for Huntington's disease
- (2016) Eduardo E. Arteaga-Bracho et al. NEUROBIOLOGY OF DISEASE
- The Biology of Huntingtin
- (2016) Frédéric Saudou et al. NEURON
- HIPPIE v2.0: enhancing meaningfulness and reliability of protein–protein interaction networks
- (2016) Gregorio Alanis-Lobato et al. NUCLEIC ACIDS RESEARCH
- Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington’s disease
- (2016) Aldrin E. Molero et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington’s disease
- (2016) Xing Guo et al. Nature Communications
- Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
- (2016) María-Victoria Hinckelmann et al. Nature Communications
- Huntingtin functions as a scaffold for selective macroautophagy
- (2015) Yan-Ning Rui et al. NATURE CELL BIOLOGY
- A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease
- (2015) Kristina Bečanović et al. NATURE NEUROSCIENCE
- ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization
- (2015) David Tse Shen Lin et al. eLife
- The Autodepalmitoylating Activity of APT Maintains the Spatial Organization of Palmitoylated Membrane Proteins
- (2014) Nachiket Vartak et al. BIOPHYSICAL JOURNAL
- Huntingtin is required for ER-to-Golgi transport and for secretory vesicle fusion at the plasma membrane
- (2014) H. Brandstaetter et al. Disease Models & Mechanisms
- Neurotrophin receptor p75NTR mediates Huntington’s disease–associated synaptic and memory dysfunction
- (2014) Verónica Brito et al. JOURNAL OF CLINICAL INVESTIGATION
- The Regulation of Autophagosome Dynamics by Huntingtin and HAP1 Is Disrupted by Expression of Mutant Huntingtin, Leading to Defective Cargo Degradation
- (2014) Y. C. Wong et al. JOURNAL OF NEUROSCIENCE
- Potential function for the Huntingtin protein as a scaffold for selective autophagy
- (2014) Joseph Ochaba et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Vesicular Glycolysis Provides On-Board Energy for Fast Axonal Transport
- (2013) Diana Zala et al. CELL
- COPII — a flexible vesicle formation system
- (2013) Elizabeth A Miller et al. CURRENT OPINION IN CELL BIOLOGY
- Mutant Huntingtin Alters Retrograde Transport of TrkB Receptors in Striatal Dendrites
- (2013) G. Liot et al. JOURNAL OF NEUROSCIENCE
- Huntingtin Acts Non Cell-Autonomously on Hippocampal Neurogenesis and Controls Anxiety-Related Behaviors in Adult Mouse
- (2013) Patrick Pla et al. PLoS One
- Embryonic stem cells neural differentiation qualifies the role of Wnt/β-Catenin signals in human telencephalic specification and regionalization
- (2013) Camille Nicoleau et al. STEM CELLS
- Releasing the brake: restoring fast axonal transport in neurodegenerative disorders
- (2013) Maria-Victoria Hinckelmann et al. TRENDS IN CELL BIOLOGY
- Confirming Target Engagement for Reversible Inhibitors in Vivo by Kinetically Tuned Activity-Based Probes
- (2012) Alexander Adibekian et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system
- (2012) Hemmo Meyer et al. NATURE CELL BIOLOGY
- Synchronization of secretory protein traffic in populations of cells
- (2012) Gaelle Boncompain et al. NATURE METHODS
- Altered palmitoylation and neuropathological deficits in mice lacking HIP14
- (2011) R. R. Singaraja et al. HUMAN MOLECULAR GENETICS
- Huntington's disease: from molecular pathogenesis to clinical treatment
- (2010) Christopher A Ross et al. LANCET NEUROLOGY
- Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
- (2010) Sarah J Tabrizi et al. LANCET NEUROLOGY
- Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
- (2010) Marta Martinez-Vicente et al. NATURE NEUROSCIENCE
- Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease
- (2010) Chiara Zuccato et al. PHYSIOLOGICAL REVIEWS
- pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking
- (2010) Raúl Pardo et al. Molecular Brain
- Mutant Huntingtin Impairs Post-Golgi Trafficking to Lysosomes by Delocalizing Optineurin/Rab8 Complex from the Golgi Apparatus
- (2009) Daniel del Toro et al. MOLECULAR BIOLOGY OF THE CELL
- A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis
- (2009) Gabriele Siegel et al. NATURE CELL BIOLOGY
- Altered white matter microstructure in the corpus callosum in Huntington's disease: Implications for cortical “disconnection”
- (2009) H. Diana Rosas et al. NEUROIMAGE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started