RhoA GTPase phosphorylated at tyrosine 42 by src kinase binds to β-catenin and contributes transcriptional regulation of vimentin upon Wnt3A

Distinct dual roles of p-Tyr42 RhoA GTPase in tau phosphorylation and ATP citrate lyase activation upon different Aβ concentrations

(2020) Kim Cuong Cap et al.   Redox Biology

c‐Met‐dependent phosphorylation of RhoA plays a key role in gastric cancer tumorigenesis

(2019) Jianjun Liu et al.   JOURNAL OF PATHOLOGY

Insulin induces phosphorylation of pyruvate dehydrogenase through RhoA activation pathway in HepG2 cells

(2018) Rokibul Islam et al.   FASEB JOURNAL

Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through nuclear factor (NF)-κB

(2017) Jae-Gyu Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA

(2017) Yaming Jiu et al.   JOURNAL OF CELL SCIENCE

Wnt3A Induces GSK-3β Phosphorylation and β-Catenin Accumulation Through RhoA/ROCK

(2016) Jae-Gyu Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Lysophosphatidic Acid Initiates Epithelial to Mesenchymal Transition and Induces β-Catenin-mediated Transcription in Epithelial Ovarian Carcinoma

(2015) Rebecca J. Burkhalter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosine phosphorylation of LRP6 by Src and Fer inhibits Wnt/ -catenin signalling

(2014) Q. Chen et al.   EMBO REPORTS

Regulation of Wnt/β-catenin signaling by posttranslational modifications

(2014) Chenxi Gao et al.   Cell and Bioscience

Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6

(2014) Jennifer L Stamos et al.   eLife

Signaling and Mechanical Roles of E-cadherin

(2013) Tanay Bhatt et al.   CELL COMMUNICATION AND ADHESION

SIRT2 overexpression in hepatocellular carcinoma mediates epithelial to mesenchymal transition by protein kinase B/glycogen synthase kinase-3β/β-catenin signaling

(2013) Juan Chen et al.   HEPATOLOGY

IκB Kinase γ/Nuclear Factor-κB-Essential Modulator (IKKγ/NEMO) Facilitates RhoA GTPase Activation, which, in Turn, Activates Rho-associated Kinase (ROCK) to Phosphorylate IKKβ in Response to Transforming Growth Factor (TGF)-β1

(2013) Hee-Jun Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

(2013) J A McCubrey et al.   LEUKEMIA

Lysophosphatidic acid activates β-catenin/T cell factor signaling, which contributes to the suppression of apoptosis in H19-7 cells

(2013) YUANJIE SUN et al.   Molecular Medicine Reports

The many faces and functions of β-catenin

(2012) Tomas Valenta et al.   EMBO JOURNAL

Small GTPases Rap1 and RhoA regulate superoxide formation by Rac1 GTPases activation during the phagocytosis of IgG-opsonized zymosans in macrophages

(2012) Yi Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity

(2012) Z.-Q. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modified SH2 domain to phototrap and identify phosphotyrosine proteins from subcellular sites within cells

(2012) A. Uezu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysophosphatidic acid 5 receptor induces activation of Na+/H+ exchanger 3 via apical epidermal growth factor receptor in intestinal epithelial cells

(2011) Byong Kwon Yoo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis

(2011) Nu Zhang et al.   CANCER CELL

Vimentin in cancer and its potential as a molecular target for cancer therapy

(2011) Arun Satelli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ras-related GTPases Rap1 and RhoA Collectively Induce the Phagocytosis of Serum-opsonized Zymosan Particles in Macrophages

(2011) Jae-Gyu Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2011) Weiwei Yang et al.   NATURE

The Small GTPase RhoA Localizes to the Nucleus and Is Activated by Net1 and DNA Damage Signals

(2011) Adi D. Dubash et al.   PLoS One

A Noncatalytic Domain of Glycogen Synthase Kinase-3 (GSK-3) Is Essential for Activity

(2010) Jessica L. Buescher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer

(2010) K Vuoriluoto et al.   ONCOGENE

Galectin-3 Mediates Nuclear β-Catenin Accumulation and Wnt Signaling in Human Colon Cancer Cells by Regulation of Glycogen Synthase Kinase-3β Activity

(2009) Shumei Song et al.   CANCER RESEARCH

Rho GTPase activity modulates Wnt3a/β-catenin signaling

(2009) Jessica Rossol-Allison et al.   CELLULAR SIGNALLING

Visualization of Src Activity at Different Compartments of the Plasma Membrane by FRET Imaging

(2009) Jihye Seong et al.   CHEMISTRY & BIOLOGY

Dishevelled-2 docks and activates Src in a Wnt-dependent manner

(2009) Noriko Yokoyama et al.   JOURNAL OF CELL SCIENCE

GSK3: a multifaceted kinase in Wnt signaling

(2009) Dianqing Wu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Rac1 Activation Controls Nuclear Localization of β-catenin during Canonical Wnt Signaling

(2008) Ximei Wu et al.   CELL

WGEF activates Rho in the Wnt–PCP pathway and controls convergent extension in Xenopus gastrulation

(2008) Kosuke Tanegashima et al.   EMBO JOURNAL

G o mediates WNT-JNK signaling through Dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells

(2008) R. K. Bikkavilli et al.   JOURNAL OF CELL SCIENCE

Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells

(2008) Pinella Buongiorno et al.   Molecular Cancer

Snail promotes Wnt target gene expression and interacts with β-catenin

(2008) V Stemmer et al.   ONCOGENE

Phosphorylation by p38 MAPK as an Alternative Pathway for GSK3  Inactivation

(2008) T. M. Thornton et al.   SCIENCE