Small-Molecule Inhibitors of the Coronavirus Spike: ACE2 Protein–Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-2
出版年份 2021 全文链接
标题
Small-Molecule Inhibitors of the Coronavirus Spike: ACE2 Protein–Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-2
作者
关键词
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出版物
ACS Infectious Diseases
Volume -, Issue -, Pages -
出版商
American Chemical Society (ACS)
发表日期
2021-05-13
DOI
10.1021/acsinfecdis.1c00070
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Methylene Blue Inhibits the SARS-CoV-2 Spike–ACE2 Protein-Protein Interaction–a Mechanism that can Contribute to its Antiviral Activity Against COVID-19
- (2021) Damir Bojadzic et al. Frontiers in Pharmacology
- Generation of SARS-CoV-2 Spike Pseudotyped Virus for Viral Entry and Neutralization Assays: A 1-Week Protocol
- (2021) Jose Manuel Condor Capcha et al. Frontiers in Cardiovascular Medicine
- SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma
- (2021) Constantinos Kurt Wibmer et al. NATURE MEDICINE
- Chloroquine for the 2019 novel coronavirus SARS-CoV-2
- (2020) Philippe Colson et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2
- (2020) Zhixin Liu et al. JOURNAL OF MEDICAL VIROLOGY
- Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine
- (2020) Wanbo Tai et al. Cellular & Molecular Immunology
- The Science Underlying COVID-19: Implications for the Cardiovascular System
- (2020) Peter P. Liu et al. CIRCULATION
- The many faces of the anti-COVID immune response
- (2020) Santosha A. Vardhana et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The many estimates of the COVID-19 case fatality rate
- (2020) Dimple D Rajgor et al. LANCET INFECTIOUS DISEASES
- Human neutralizing antibodies elicited by SARS-CoV-2 infection
- (2020) Bin Ju et al. NATURE
- Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
- (2020) Jun Lan et al. NATURE
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- Cell entry mechanisms of SARS-CoV-2
- (2020) Jian Shang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytokine release syndrome in severe COVID-19
- (2020) John B. Moore et al. SCIENCE
- Rapid repurposing of drugs for COVID-19
- (2020) R. Kiplin Guy et al. SCIENCE
- A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
- (2020) Yan Wu et al. SCIENCE
- Estimating the burden of SARS-CoV-2 in France
- (2020) Henrik Salje et al. SCIENCE
- A human monoclonal antibody blocking SARS-CoV-2 infection
- (2020) Chunyan Wang et al. Nature Communications
- Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
- (2020) Xiuyuan Ou et al. Nature Communications
- Sirtuin 1 Inhibiting Thiocyanates (S1th)—A New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases
- (2020) Nathalie Wössner et al. Frontiers in Oncology
- Structural Basis of the SARS-CoV-2/SARS-CoV Receptor Binding and Small-Molecule Blockers as Potential Therapeutics
- (2020) Hariharan Sivaraman et al. Annual Review of Pharmacology and Toxicology
- Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle
- (2020) Clarisse Salgado-Benvindo et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Discovering small-molecule therapeutics against SARS-CoV-2
- (2020) Vaibhav Tiwari et al. DRUG DISCOVERY TODAY
- Immune checkpoint inhibitors: a physiology-driven approach to the treatment of coronavirus disease 2019
- (2020) Serena Di Cosimo et al. EUROPEAN JOURNAL OF CANCER
- The pathogenesis and treatment of the `Cytokine Storm' in COVID-19
- (2020) Qing Ye et al. JOURNAL OF INFECTION
- COVID-19: Drug Targets and Potential Treatments
- (2020) Carmen Gil et al. JOURNAL OF MEDICINAL CHEMISTRY
- Inhibitors of SARS-CoV-2 Entry: Current and Future Opportunities
- (2020) Siyu Xiu et al. JOURNAL OF MEDICINAL CHEMISTRY
- A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2–spike protein–protein interaction
- (2020) Chee Wah Tan et al. NATURE BIOTECHNOLOGY
- Candidate drugs against SARS-CoV-2 and COVID-19
- (2020) Dwight L. McKee et al. PHARMACOLOGICAL RESEARCH
- Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies
- (2020) Alina Baum et al. SCIENCE
- Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody
- (2020) Zhe Lv et al. SCIENCE
- Broad neutralization of SARS-related viruses by human monoclonal antibodies
- (2020) Anna Z. Wec et al. SCIENCE
- Structural basis of a shared antibody response to SARS-CoV-2
- (2020) Meng Yuan et al. SCIENCE
- How does SARS-CoV-2 cause COVID-19?
- (2020) Nicholas J. Matheson et al. SCIENCE
- A single unified model for fitting simple to complex receptor response data
- (2020) Peter Buchwald Scientific Reports
- Methylene blue inhibits the replication of SARS-Cov-2 in vitro
- (2020) Mathieu Gendrot et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Cytokine release syndrome in COVID-19: Innate immune, vascular, and platelet pathogenic factors differ in severity of disease and sex
- (2020) Aaron C. Petrey et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Autoantibodies against type I IFNs in patients with life-threatening COVID-19
- (2020) Paul Bastard et al. SCIENCE
- COVID-19: Infection or Autoimmunity
- (2020) Timothy Icenogle Frontiers in Immunology
- Antibody-like proteins that capture and neutralize SARS-CoV-2
- (2020) T. Kondo et al. Science Advances
- Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
- (2020) NEW ENGLAND JOURNAL OF MEDICINE
- Structural basis for human coronavirus attachment to sialic acid receptors
- (2019) M. Alejandra Tortorici et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- CD40-targeting KGYY15 peptides do not efficiently block the CD40–CD40L interaction
- (2019) Damir Bojadzic et al. DIABETOLOGIA
- New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology
- (2019) Martin C. Michel et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Small Molecules Drive Big Improvements in Immuno-Oncology Therapies
- (2018) Bayard R. Huck et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers
- (2018) Michael J Curtis et al. BRITISH JOURNAL OF PHARMACOLOGY
- Toward Small-Molecule Inhibition of Protein–Protein Interactions: General Aspects and Recent Progress in Targeting Costimulatory and Coinhibitory (Immune Checkpoint) Interactions
- (2018) Damir Bojadzic et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial
- (2018) Alassane Dicko et al. LANCET INFECTIOUS DISEASES
- Design, Synthesis, and Evaluation of Novel Immunomodulatory Small Molecules Targeting the CD40–CD154 Costimulatory Protein-Protein Interaction
- (2018) Damir Bojadzic et al. MOLECULES
- Postmarket Safety Events Among Novel Therapeutics Approved by the US Food and Drug Administration Between 2001 and 2010
- (2017) Nicholas S. Downing et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Phantom PAINS: Problems with the Utility of Alerts for Pan-Assay INterference CompoundS
- (2017) Stephen J. Capuzzi et al. Journal of Chemical Information and Modeling
- Beyond the Rule of 5: Lessons Learned from AbbVie’s Drugs and Compound Collection
- (2017) David A. DeGoey et al. JOURNAL OF MEDICINAL CHEMISTRY
- Small-Molecule Inhibitors of the CD40–CD40L Costimulatory Protein–Protein Interaction
- (2017) Jinshui Chen et al. JOURNAL OF MEDICINAL CHEMISTRY
- Inhibitors of HIV-1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir
- (2017) Nicholas A. Meanwell et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Current State of Peptide Drug Discovery: Back to the Future?
- (2017) Antoine Henninot et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Ecstasy and Agony of Assay Interference Compounds
- (2017) Courtney Aldrich et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeted protein degradation by PROTACs
- (2017) Taavi K. Neklesa et al. PHARMACOLOGY & THERAPEUTICS
- Toremifene interacts with and destabilizes the Ebola virus glycoprotein
- (2016) Yuguang Zhao et al. NATURE
- Pioneering apoptosis-targeted cancer drug poised for FDA approval
- (2016) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Small molecules, big targets: drug discovery faces the protein–protein interaction challenge
- (2016) Duncan E. Scott et al. NATURE REVIEWS DRUG DISCOVERY
- Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions
- (2015) Luca Laraia et al. CHEMISTRY & BIOLOGY
- TNF Superfamily Protein-Protein Interactions: Feasibility of Small- Molecule Modulation
- (2015) Yun Song et al. CURRENT DRUG TARGETS
- Small-molecule modulators of the OX40-OX40 ligand co-stimulatory protein-protein interaction
- (2014) Yun Song et al. BRITISH JOURNAL OF PHARMACOLOGY
- Modulators of Protein–Protein Interactions
- (2014) Lech-Gustav Milroy et al. CHEMICAL REVIEWS
- Effects of Human Anti-Spike Protein Receptor Binding Domain Antibodies on Severe Acute Respiratory Syndrome Coronavirus Neutralization Escape and Fitness
- (2014) J. Sui et al. JOURNAL OF VIROLOGY
- Chemistry: Chemical con artists foil drug discovery
- (2014) Jonathan Baell et al. NATURE
- Targeting Membrane-Bound Viral RNA Synthesis Reveals Potent Inhibition of Diverse Coronaviruses Including the Middle East Respiratory Syndrome Virus
- (2014) Anna Lundin et al. PLoS Pathogens
- Current challenges in peptide-based drug discovery
- (2014) Laszlo Otvos et al. Frontiers in Chemistry
- Novel Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Entry That Act by Three Distinct Mechanisms
- (2013) A. O. Adedeji et al. JOURNAL OF VIROLOGY
- ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
- (2013) Andrew J Souers et al. NATURE MEDICINE
- Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex
- (2013) Q. Tan et al. SCIENCE
- Patient preferences and willingness to pay for different options of anticoagulant therapy
- (2012) Marco Moia et al. Internal and Emergency Medicine
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- The food colorant erythrosine is a promiscuous protein–protein interaction inhibitor
- (2011) Lakshmi Ganesan et al. BIOCHEMICAL PHARMACOLOGY
- Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA)
- (2011) Muthusamy Venkatraj et al. BIOORGANIC & MEDICINAL CHEMISTRY
- “Lest we forget you — methylene blue …”
- (2011) R. Heiner Schirmer et al. NEUROBIOLOGY OF AGING
- Small-molecule protein-protein interaction inhibitors: Therapeutic potential in light of molecular size, chemical space, and ligand binding efficiency considerations
- (2010) Peter Buchwald IUBMB LIFE
- Designing Focused Chemical Libraries Enriched in Protein-Protein Interaction Inhibitors using Machine-Learning Methods
- (2010) Christelle Reynès et al. PLoS Computational Biology
- Suramin inhibits the CD40–CD154 costimulatory interaction: A possible mechanism for immunosuppressive effects
- (2009) Emilio Margolles-Clark et al. BIOCHEMICAL PHARMACOLOGY
- Rationalizing the chemical space of protein–protein interaction inhibitors
- (2009) Olivier Sperandio et al. DRUG DISCOVERY TODAY
- Small-molecule costimulatory blockade: organic dye inhibitors of the CD40–CD154 interaction
- (2009) Emilio Margolles-Clark et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- The spike protein of SARS-CoV — a target for vaccine and therapeutic development
- (2009) Lanying Du et al. NATURE REVIEWS MICROBIOLOGY
- Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond
- (2008) Nick Giannoukakis et al. PEDIATRIC DIABETES
- Protein therapeutics: a summary and pharmacological classification
- (2007) Benjamin Leader et al. NATURE REVIEWS DRUG DISCOVERY
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