Predicting antimicrobial mechanism-of-action from transcriptomes: A generalizable explainable artificial intelligence approach

Mechanism-of-Action Classification of Antibiotics by Global Transcriptome Profiling

(2020) Aubrie O’Rourke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Science of Antibiotic Discovery

(2020) Kim Lewis   CELL

Metal‐responsive RNA polymerase extracytoplasmic function ( ECF ) sigma factors

(2019) Aurelio Moraleda‐Muñoz et al.   MOLECULAR MICROBIOLOGY

Thermal proteome profiling in bacteria: probing protein state in vivo

(2018) André Mateus et al.   Molecular Systems Biology

High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds

(2018) Mattia Zampieri et al.   Science Translational Medicine

Feathermoss and epiphytic Nostoc cooperate differently: expanding the spectrum of plant–cyanobacteria symbiosis

(2017) Denis Warshan et al.   ISME Journal

Reducing the Bottleneck in Discovery of Novel Antibiotics

(2016) Marcus B. Jones et al.   MICROBIAL ECOLOGY

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins

(2016) Long Han et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins

(2016) Long Han et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A new antibiotic kills pathogens without detectable resistance

(2015) Losee L. Ling et al.   NATURE

Antibiotic resistance—the need for global solutions

(2013) Ramanan Laxminarayan et al.   LANCET INFECTIOUS DISEASES

Mechanism of action-based classification of antibiotics using high-content bacterial image analysis

(2013) Kelly C. Peach et al.   Molecular BioSystems

Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules

(2013) P. Nonejuie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Challenges of Antibacterial Discovery

(2011) L. L. Silver   CLINICAL MICROBIOLOGY REVIEWS

Staphylococcus aureus TargetArray: Comprehensive Differential Essential Gene Expression as a Mechanistic Tool To Profile Antibacterials

(2010) H. H. Xu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Origins and Evolution of Antibiotic Resistance

(2010) J. Davies et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Hierarchical Ensemble of Global and Local Classifiers for Face Recognition

(2009) Yu Su et al.   IEEE TRANSACTIONS ON IMAGE PROCESSING

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS