Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors
出版年份 2021 全文链接
标题
Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors
作者
关键词
CDK4/6 inhibitors, palbociclib, chemokines, CCL5, ROS, cancer metabolism, metabolic stress, anti-tumor immunity, adoptive cell transfer
出版物
Cell Reports
Volume 35, Issue 1, Pages 108944
出版商
Elsevier BV
发表日期
2021-04-06
DOI
10.1016/j.celrep.2021.108944
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- mTOR at the nexus of nutrition, growth, ageing and disease
- (2020) Grace Y. Liu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanisms of Sensitivity and Resistance to CDK4/6 Inhibition
- (2020) Mónica Álvarez-Fernández et al. CANCER CELL
- TIMER2.0 for analysis of tumor-infiltrating immune cells
- (2020) Taiwen Li et al. NUCLEIC ACIDS RESEARCH
- Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors
- (2019) Denarda Dangaj et al. CANCER CELL
- MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21
- (2019) Anna E. Vilgelm et al. Science Translational Medicine
- SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors
- (2019) Akihiro Yoshida et al. Science Advances
- Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR+/HER2− Breast Cancer
- (2019) Sara A. Hurvitz et al. CLINICAL CANCER RESEARCH
- CDK4/6 Inhibitors: The Mechanism of Action May Not Be as Simple as Once Thought
- (2018) Mary E. Klein et al. CANCER CELL
- NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
- (2018) Jan P. Böttcher et al. CELL
- Reactive Oxygen Species in Metabolic and Inflammatory Signaling
- (2018) Steven J. Forrester et al. CIRCULATION RESEARCH
- Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape
- (2018) Max D. Wellenstein et al. IMMUNITY
- The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells
- (2018) Daniele Cretella et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade
- (2018) David A. Schaer et al. Cell Reports
- Impact of chemotactic factors and receptors on the cancer immune infiltrate: a bioinformatics study revealing homogeneity and heterogeneity among patient cohorts
- (2018) Gautier Stoll et al. OncoImmunology
- The Role of Reactive Oxygen Species in Regulating T Cell-mediated Immunity and Disease
- (2018) Emily L. Yarosz et al. Immune Network
- Arrested Developments: CDK4/6 Inhibitor Resistance and Alterations in the Tumor Immune Microenvironment
- (2018) Jessica L.F. Teh et al. CLINICAL CANCER RESEARCH
- Overall Survival with Palbociclib and Fulvestrant in Advanced Breast Cancer
- (2018) Nicholas C. Turner et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pan-tumor genomic biomarkers for PD-1 checkpoint blockade–based immunotherapy
- (2018) Razvan Cristescu et al. SCIENCE
- Correction: In Vivo E2F Reporting Reveals Efficacious Schedules of MEK1/2–CDK4/6 Targeting and mTOR–S6 Resistance Mechanisms
- (2018) Jessica L.F. Teh et al. Cancer Discovery
- Mitochondria, Oxidative Stress and Innate Immunity
- (2018) Yuxin Chen et al. Frontiers in Physiology
- IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade
- (2017) Mark Ayers et al. JOURNAL OF CLINICAL INVESTIGATION
- De novo MYC addiction as an adaptive response of cancer cells to CDK4/6 inhibition
- (2017) Míriam Tarrado‐Castellarnau et al. Molecular Systems Biology
- CDK4/6 inhibition triggers anti-tumour immunity
- (2017) Shom Goel et al. NATURE
- Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance
- (2017) Jinfang Zhang et al. NATURE
- Twenty-five years of mTOR: Uncovering the link from nutrients to growth
- (2017) David M. Sabatini PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
- (2017) Jiehui Deng et al. Cancer Discovery
- Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease
- (2017) Filippo Scialò et al. Frontiers in Physiology
- MDM2 Antagonists Counteract Drug-Induced DNA Damage
- (2017) Anna E. Vilgelm et al. EBioMedicine
- Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors
- (2016) Shom Goel et al. CANCER CELL
- Combinatorial approach to cancer immunotherapy: strength in numbers
- (2016) Anna E. Vilgelm et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial
- (2016) Massimo Cristofanilli et al. LANCET ONCOLOGY
- Metabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique Vulnerabilities
- (2016) Jorge Franco et al. Cell Reports
- Relevance of tumor-infiltrating lymphocytes in breast cancer
- (2015) Sathana Dushyanthen et al. BMC Medicine
- Robust enumeration of cell subsets from tissue expression profiles
- (2015) Aaron M Newman et al. NATURE METHODS
- Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity
- (2014) Jason W. Griffith et al. Annual Review of Immunology
- Effects of the mTOR inhibitor Rapamycin on Monocyte-Secreted Chemokines
- (2014) Hugo You-Hsien Lin et al. BMC IMMUNOLOGY
- Mdm2 and Aurora Kinase A Inhibitors Synergize to Block Melanoma Growth by Driving Apoptosis and Immune Clearance of Tumor Cells
- (2014) A. E. Vilgelm et al. CANCER RESEARCH
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- Chemokines in Cancer
- (2014) M. T. Chow et al. Cancer Immunology Research
- The role of oxidative stress during inflammatory processes
- (2013) Jérôme Lugrin et al. BIOLOGICAL CHEMISTRY
- mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation
- (2013) Masahiro Morita et al. Cell Metabolism
- Staying alive
- (2012) James R. Valcourt et al. CELL CYCLE
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Cyclin-dependent kinases 4 and 6 control tumor progression and direct glucose oxidation in the pentose cycle
- (2011) Miriam Zanuy et al. Metabolomics
- mTOR Signaling
- (2011) M. Laplante et al. Cold Spring Harbor Perspectives in Biology
- CC Chemokine Receptor 5 (CCR5) Desensitization
- (2010) Jean-Michel Escola et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cellular Metabolic Stress: Considering How Cells Respond to Nutrient Excess
- (2010) Kathryn E. Wellen et al. MOLECULAR CELL
- Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment
- (2009) H. Harlin et al. CANCER RESEARCH
- Mitochondria in cancer cells: what is so special about them?
- (2008) Vladimir Gogvadze et al. TRENDS IN CELL BIOLOGY
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