Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells

Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

(2020) Yushun Wan et al.   JOURNAL OF VIROLOGY

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Clinical Features of Maintenance Hemodialysis Patients with 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China

(2020) Jun Wu et al.   Clinical Journal of the American Society of Nephrology

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

Isolation and rapid sharing of the 2019 novel coronavirus ( SARS ‐CoV‐2) from the first patient diagnosed with COVID ‐19 in Australia

(2020) Leon Caly et al.   MEDICAL JOURNAL OF AUSTRALIA

Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study

(2020) Christopher M Petrilli et al.   BMJ-British Medical Journal

Do chronic respiratory diseases or their treatment affect the risk of SARS-CoV-2 infection?

(2020) David M G Halpin et al.   Lancet Respiratory Medicine

Single-cell RNA Expression Profiling of ACE2, The Receptor of SARS-CoV-2

(2020) Yu Zhao et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

(2020) Bette Korber et al.   CELL

Efficacy and Safety of Daprodustat Compared with Darbepoetin Alfa in Japanese Hemodialysis Patients with Anemia

(2020) Tadao Akizawa et al.   Clinical Journal of the American Society of Nephrology

Characteristics and predictors of death among 4,035 consecutively hospitalized patients with COVID-19 in Spain

(2020) Juan Berenguer et al.   CLINICAL MICROBIOLOGY AND INFECTION

Phase 3, Randomized, Double-Blind, Active-Comparator (Darbepoetin Alfa) Study of Oral Roxadustat in CKD Patients with Anemia on Hemodialysis in Japan

(2020) Tadao Akizawa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Factors associated with COVID-19-related death using OpenSAFELY

(2020) Elizabeth J. Williamson et al.   NATURE

Chronic obstructive pulmonary disease is associated with severe coronavirus disease 2019 (COVID-19)

(2020) Giuseppe Lippi et al.   RESPIRATORY MEDICINE

Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein

(2020) Andrew D. Davidson et al.   Genome Medicine

Hypoxic microenvironment shapes HIV-1 replication and latency

(2020) Xiaodong Zhuang et al.   Communications Biology

Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis

(2020) Ana Campos Codo et al.   Cell Metabolism

Underlying respiratory diseases, specifically COPD, and smoking are associated with severe COVID-19 outcomes: A systematic review and meta-analysis

(2020) Diana C. Sanchez-Ramirez et al.   RESPIRATORY MEDICINE

D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization

(2020) Drew Weissman et al.   Cell Host & Microbe

MiRNA let-7b promotes the development of hypoxic pulmonary hypertension by targeting ACE2

(2019) Ruifeng Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis

(2019) Gunnar Schley et al.   KIDNEY INTERNATIONAL

Hypoxic regulation of angiotensin‐converting enzyme 2 and Mas receptor in human CD34 + cells

(2019) Shrinidh Joshi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis

(2019) Nan Chen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis

(2019) Nan Chen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intermittent Oral Dosing of Roxadustat in Peritoneal Dialysis Chronic Kidney Disease Patients with Anemia: A Randomized, Phase 3, Multicenter, Open‐Label Study

(2019) Tadao Akizawa et al.   THERAPEUTIC APHERESIS AND DIALYSIS

Hypoxia-Inducible Factor Activators in Renal Anemia: Current Clinical Experience

(2019) Neil S. Sanghani et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

The Role of Tissue Oxygen Tension in Dengue Virus Replication

(2018) Efseveia Frakolaki et al.   Cells

New horizons in hypoxia signaling pathways

(2017) Christopher W. Pugh et al.   EXPERIMENTAL CELL RESEARCH

Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication

(2017) Michelle J. Farquhar et al.   JOURNAL OF HEPATOLOGY

Single molecule fluorescence in situ hybridisation for quantitating post-transcriptional regulation in Drosophila brains

(2017) Lu Yang et al.   METHODS

Enzymatic production of single-molecule FISH and RNA capture probes

(2017) Imre Gaspar et al.   RNA

Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus’s natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter

(2017) Richard J. Kraus et al.   PLoS Pathogens

Oral Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat (FG-4592) for the Treatment of Anemia in Patients with CKD

(2016) R. Provenzano et al.   Clinical Journal of the American Society of Nephrology

HIF Transcription Factors, Inflammation, and Immunity

(2014) Asis Palazon et al.   IMMUNITY

Epigenetic regulation of angiotensin-converting enzyme 2 (ACE2) by SIRT1 under conditions of cell energy stress

(2013) Nicola E. Clarke et al.   CLINICAL SCIENCE

The von Hippel–Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice

(2010) Michele M. Hickey et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of HIF-1α in the regulation ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells

(2009) Ruifeng Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL