High-throughput drug screening reveals Pyrvinium pamoate as effective candidate against pediatric MLL-rearranged acute myeloid leukemia

Synthesis and efficacy of pyrvinium-inspired analogs against tuberculosis and malaria pathogens

(2020) Vikas R. Gaikwad et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pyrvinium Pamoate Use in a B cell Acute Lymphoblastic Leukemia Model of the Bone Tumor Microenvironment

(2020) Rajesh R. Nair et al.   PHARMACEUTICAL RESEARCH

β-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells

(2020) Xin Zhao et al.   eLife

CDK9 inhibitors in acute myeloid leukemia

(2018) Silvia Boffo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The novel role of pyrvinium in cancer therapy

(2017) Amir A. Momtazi-borojeni et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pyrvinium selectively induces apoptosis of lymphoma cells through impairing mitochondrial functions and JAK2/STAT5

(2016) Meifang Xiao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

(2016) D. A. Arber et al.   BLOOD

Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia

(2016) Zizhen Feng et al.   Journal of Hematology & Oncology

Current Management of Childhood Acute Myeloid Leukemia

(2016) Jeffrey E. Rubnitz   PEDIATRIC DRUGS

Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia

(2015) C. Michel Zwaan et al.   JOURNAL OF CLINICAL ONCOLOGY

Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration

(2015) Wei Xiang et al.   Oncotarget

The Antihelmintic Drug Pyrvinium Pamoate Targets Aggressive Breast Cancer

(2013) Wei Xu et al.   PLoS One

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Results of a randomized trial in children with Acute Myeloid Leukaemia: Medical Research Council AML12 trial

(2011) Brenda E. S. Gibson et al.   BRITISH JOURNAL OF HAEMATOLOGY

Pyrvinium pamoate inhibits proliferation of myeloma/erythroleukemia cells by suppressing mitochondrial respiratory complex I and STAT3

(2011) Yasuo Harada et al.   CANCER LETTERS

The Role of HDACs Inhibitors in Childhood and Adolescence Acute Leukemias

(2011) Riccardo Masetti et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Favourable outcome of patients with childhood acute promyelocytic leukaemia after treatment with reduced cumulative anthracycline doses

(2010) Ursula Creutzig et al.   BRITISH JOURNAL OF HAEMATOLOGY

Response-Guided Induction Therapy in Pediatric Acute Myeloid Leukemia With Excellent Remission Rate

(2010) Jonas Abrahamsson et al.   JOURNAL OF CLINICAL ONCOLOGY

Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: results of the AML02 multicentre trial

(2010) Jeffrey E Rubnitz et al.   LANCET ONCOLOGY

Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study

(2009) B. V. Balgobind et al.   BLOOD

Update on Hsp90 Inhibitors in Clinical Trial

(2009) Y. Kim et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Risk-Stratified Therapy and the Intensive Use of Cytarabine Improves the Outcome in Childhood Acute Myeloid Leukemia: The AML99 Trial From the Japanese Childhood AML Cooperative Study Group

(2009) Ichiro Tsukimoto et al.   JOURNAL OF CLINICAL ONCOLOGY

Pyrvinium Targets the Unfolded Protein Response to Hypoglycemia and Its Anti-Tumor Activity Is Enhanced by Combination Therapy

(2008) De-Hua Yu et al.   PLoS One