4.7 Article

Formation of toxic iodinated by-products during the oxidation process of iohexol by catalytic ozonation in water

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ELSEVIER
DOI: 10.1016/j.seppur.2020.118287

关键词

Iohexol; Catalytic ozonation; Iodinated by-products; Degradation mechanism

资金

  1. National Key R&D Program of China [2019YFD1100104, 2017YFA0207203, 2017YFA0207204]
  2. State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology [QA201817]
  3. Science Foundation of Heilongjiang Academy of Science [KY2020ZR01]
  4. National Natural Science Foundation of China [52000047]

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This study investigated the generation mechanism of iodinated by-products during catalytic ozonation of iohexol, and evaluated the impact of various factors on their generation. The concentrations of iodinated by-products in actual water were relatively low, and the species with one iodide atom had significantly higher generation concentrations than those with more iodine atoms.
The formation of iodinated by-products during the chemical oxidation process for organic compounds contaminated water has gained increasing attention. Iodinated by-products are more genotoxic, cytotoxic and mutagenic than those of chlorine and bromine analogs. It was reported that the oxidation process of iodinated Xray contrast media (ICM) could generate iodinated by-products. This study investigated the generation of iodinated by-products during catalytic ozonation of iohexol (one of wide detected ICM). The formation of iodoform (IF) and monoiodoacetic acid (MIAA), and the degradation kinetics of iohexol were compared in different oxidation systems. The effect of various factors, including the iohexol concentration, ozone concentration, HA concentration and solution pH on iodinated by-products generation was evaluated. Additionally, the fate of iodine was investigated by the mass balance calculation. The generated concentrations of I-THMs species with one iodide atom were far higher than those of species with more iodine atoms in the catalytic system at the coexistence of Cl- and Br-. The generation of I-THMs in actual water was relatively low and the normalized value of I-THMs/DOC (mu g/mg) had no significant difference. The formation mechanism of high molecular weight iodine-containing by-products included cleavage of the side chain, H-abstraction, substitution iodine for chlorine or bromine and amide oxidation.

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