Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification

Application of induced pluripotent stem cells to primary immunodeficiency diseases

(2019) Peter Karagiannis et al.   EXPERIMENTAL HEMATOLOGY

Pluripotent Stem Cell Model of Nakajo-Nishimura Syndrome Untangles Proinflammatory Pathways Mediated by Oxidative Stress

(2018) Fumiko Honda-Ozaki et al.   Stem Cell Reports

Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors

(2017) Sergei Doulatov et al.   Science Translational Medicine

CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs

(2016) Mohammad A. Mandegar et al.   Cell Stem Cell

Systematic Cellular Disease Models Reveal Synergistic Interaction of Trisomy 21 and GATA1 Mutations in Hematopoietic Abnormalities

(2016) Kimihiko Banno et al.   Cell Reports

Rapid Protein Depletion in Human Cells by Auxin-Inducible Degron Tagging with Short Homology Donors

(2016) Toyoaki Natsume et al.   Cell Reports

Transient Abnormal Myelopoiesis and AML in Down Syndrome: an Update

(2016) Neha Bhatnagar et al.   Current Hematologic Malignancy Reports

Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells

(2016) Ryo Ohta et al.   Scientific Reports

Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus

(2015) Marta Byrska-Bishop et al.   JOURNAL OF CLINICAL INVESTIGATION

Pluripotent Cell Models of Fanconi Anemia Identify the Early Pathological Defect in Human Hemoangiogenic Progenitors

(2015) Naoya M. Suzuki et al.   Stem Cells Translational Medicine

Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies

(2014) Yasuhiro Kazuki et al.   Scientific Reports

GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia

(2013) I. Roberts et al.   BLOOD

GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia

(2013) A Maroz et al.   LEUKEMIA

The landscape of somatic mutations in Down syndrome–related myeloid disorders

(2013) Kenichi Yoshida et al.   NATURE GENETICS

Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971

(2011) A. S. Gamis et al.   BLOOD

Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder: mutation classes correlate with progression to myeloid leukemia

(2010) R. Kanezaki et al.   BLOOD

Acute megakaryoblastic leukaemia (AMKL) and transient myeloproliferative disorder (TMD) in Down syndrome: a multi-step model of myeloid leukaemogenesis

(2009) Anindita Roy et al.   BRITISH JOURNAL OF HAEMATOLOGY

Treatment and prognostic impact of transient leukemia in neonates with Down syndrome

(2008) J.-H. Klusmann et al.   BLOOD

Risk factors for early death in neonates with Down syndrome and transient leukaemia

(2008) Hideki Muramatsu et al.   BRITISH JOURNAL OF HAEMATOLOGY