Neuroprotective effects of aucubin on hydrogen peroxide-induced toxicity in human neuroblastoma SH-SY5Y cells via the Nrf2/HO-1 pathway

Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF

(2020) Pradeep Ramalingam et al.   Nature Communications

Pro-survival and anti-inflammatory roles of NF-κB c-Rel in the Parkinson's disease models

(2020) Zishan Wang et al.   Redox Biology

A novel target TAX1BP1 and P38/Nrf2 pathway independently involved in the anti-neuroinflammatory effect of isobavachalcone

(2020) Zhipeng Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury

(2020) Han Wang et al.   Journal of Neuroinflammation

Counteracting role of nuclear factor erythroid 2-related factor 2 pathway in Alzheimer's disease

(2020) Veerta Sharma et al.   BIOMEDICINE & PHARMACOTHERAPY

Anthocyanin ameliorates hypoxia and ischemia induced inflammation and apoptosis by increasing autophagic flux in SH-SY5Y cells

(2020) Yiyu Cai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Metformin alleviates lead-induced mitochondrial fragmentation via AMPK/Nrf2 activation in SH-SY5Y cells

(2020) Luoyao Yang et al.   Redox Biology

ROS systems are a new integrated network for sensing homeostasis and alarming stresses in organelle metabolic processes

(2020) Yu Sun et al.   Redox Biology

Novel compound VB-037 inhibits Aβ aggregation and promotes neurite outgrowth through enhancement of HSP27 and reduction of P38 and JNK-mediated inflammation in cell models for Alzheimer's disease

(2019) Ya-Jen Chiu et al.   NEUROCHEMISTRY INTERNATIONAL

FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Protects against Oxidative Stress-Mediated Neuronal Cell Apoptosis and Scopolamine-Induced Cognitive Impairment by Activating Nrf2/HO-1 Signaling

(2019) Ting Wan et al.   Oxidative Medicine and Cellular Longevity

The dietary triterpenoid 18α–Glycyrrhetinic acid protects from MMC-induced genotoxicity through the ERK/Nrf2 pathway

(2019) Maria Lefaki et al.   Redox Biology

Nrf2-Keap1 signaling in oxidative and reductive stress

(2018) Ilaria Bellezza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Aucubin protects against lipopolysaccharide-induced acute pulmonary injury through regulating Nrf2 and AMPK pathways

(2018) Yan-Ling Qiu et al.   BIOMEDICINE & PHARMACOTHERAPY

NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches

(2018) Farzane Sivandzade et al.   Redox Biology

The therapeutic effect of aucubin-supplemented hyaluronic acid on interleukin-1beta-stimulated human articular chondrocytes

(2018) Teng-Le Huang et al.   PHYTOMEDICINE

Suppressed ubiquitination of Nrf2 by p47 phox contributes to Nrf2 activation

(2017) Kyun Ha Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 in keratinocytes modulates UVB-induced DNA damage and apoptosis in melanocytes through MAPK signaling

(2017) Saowanee Jeayeng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sulforaphane Promotes Mitochondrial Protection in SH-SY5Y Cells Exposed to Hydrogen Peroxide by an Nrf2-Dependent Mechanism

(2017) Marcos Roberto de Oliveira et al.   MOLECULAR NEUROBIOLOGY

Redox activation of Nrf2 & NF-κB: A double end sword?

(2013) Mabel Buelna-Chontal et al.   CELLULAR SIGNALLING

Aucubin, a naturally occurring iridoid glycoside inhibits TNF-α-induced inflammatory responses through suppression of NF-κB activation in 3T3-L1 adipocytes

(2013) Kyoung Sik Park   CYTOKINE

Transcription factor Nrf2 suppresses LPS-induced hyperactivation of BV-2 microglial cells

(2011) Kyungmi Koh et al.   JOURNAL OF NEUROIMMUNOLOGY

Protective Effects of Aucubin on H2O2-Induced Apoptosis in PC12 Cells

(2011) Hong-Yu Xue et al.   PHYTOTHERAPY RESEARCH

X-ray crystal structure of iridoid glucoside aucubin and its aglycone

(2009) Yang Li et al.   CARBOHYDRATE RESEARCH

Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?

(2008) Helga E. de Vries et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species production and MAPK activation are implicated in tetrahydrobiopterin-induced SH-SY5Y cell death

(2008) Vasutakarn Chongthammakun et al.   NEUROSCIENCE LETTERS