Tackling neurodegenerative diseases with genomic engineering: A new stem cell initiative from the NIH

In vitro Models of Neurodegenerative Diseases

(2020) Anna Slanzi et al.   Frontiers in Cell and Developmental Biology

A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ

(2019) Dylan Kwart et al.   NEURON

A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies

(2019) Celeste M. Karch et al.   Stem Cell Reports

PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia

(2019) Henna Konttinen et al.   Stem Cell Reports

iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases

(2017) Edsel M. Abud et al.   NEURON

Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening

(2017) Chao Wang et al.   Stem Cell Reports

CRISPR/Cas9 for Human Genome Engineering and Disease Research

(2016) Xin Xiong et al.   Annual Review of Genomics and Human Genetics

The human-induced pluripotent stem cell initiative—data resources for cellular genetics

(2016) Ian Streeter et al.   NUCLEIC ACIDS RESEARCH

The Parkinson Progression Marker Initiative (PPMI)

(2011) Kenneth Marek et al.   PROGRESS IN NEUROBIOLOGY