A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ

出版年份 2019 全文链接

标题

作者

关键词

Alzheimer’s disease, amyloid-beta, Aβ, presenilin, endocytosis, beta-C-terminal fragment, β-CTF, induced pluripotent stem cell, amyloid precursor protein, CRISPR/Cas9, Rab5

出版物

NEURON

Volume -, Issue -, Pages -

出版商

Elsevier BV

发表日期

2019-08-12

DOI

10.1016/j.neuron.2019.07.010

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