Modulation of vascular integrity and neuroinflammation by peroxiredoxin 4 following cerebral ischemia-reperfusion injury

Absence of MCP-induced Protein 1 Enhances Blood–Brain Barrier Breakdown after Experimental Stroke in Mice

(2019) Zhuqing Jin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Essential role of the peroxiredoxin 4 in Procambarus clarkii antioxidant defense and immune responses

(2018) Li-Shang Dai et al.   FISH & SHELLFISH IMMUNOLOGY

NXY-059, a Failed Stroke Neuroprotectant, Offers No Protection to Stem Cell-Derived Human Neurons

(2018) Ana Antonic et al.   Journal of Stroke & Cerebrovascular Diseases

NXY-059, a Failed Stroke Neuroprotectant, Offers No Protection to Stem Cell-Derived Human Neurons

(2018) Ana Antonic et al.   Journal of Stroke & Cerebrovascular Diseases

Rat Pial Microvascular Changes During Cerebral Blood Flow Decrease and Recovery: Effects of Cyanidin Administration

(2018) Teresa Mastantuono et al.   Frontiers in Physiology

Isoflurane preconditioning inhibits the effects of tissue-type plasminogen activator on brain endothelial cell in an in vitro model of ischemic stroke

(2017) So Yeong Cheon et al.   International Journal of Medical Sciences

Targeting antioxidant enzyme expression as a therapeutic strategy for ischemic stroke

(2017) Stephanie M. Davis et al.   NEUROCHEMISTRY INTERNATIONAL

Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity

(2017) Qiu-Yan Zhang et al.   Oxidative Medicine and Cellular Longevity

Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood–brain barrier disruption after ischemic brain injury

(2017) Yejie Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enzymatic antioxidant system of endotheliocytes

(2016) M. G. Sharapov et al.   Doklady Biochemistry and Biophysics

Activation of classical estrogen receptor subtypes reduces tight junction disruption of brain endothelial cells under ischemia/reperfusion injury

(2016) Jin A. Shin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inflammatory risk factors, biomarkers and associated therapy in ischaemic stroke

(2016) Charles C. Esenwa et al.   Nature Reviews Neurology

Endovascular Therapy in Acute Ischemic Stroke

(2016) Mayank Goyal et al.   STROKE

Blockade of Apoptosis Signal-Regulating Kinase 1 Attenuates Matrix Metalloproteinase 9 Activity in Brain Endothelial Cells and the Subsequent Apoptosis in Neurons after Ischemic Injury

(2016) So Y. Cheon et al.   Frontiers in Cellular Neuroscience

Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

(2016) Yejie Shi et al.   Nature Communications

Effects of Citrus Flavonoids Against Microvascular Damage Induced by Hypoperfusion and Reperfusion in Rat Pial Circulation

(2015) Teresa Mastantuono et al.   MICROCIRCULATION

Effects of Oleuropein and Pinoresinol on Microvascular Damage Induced by Hypoperfusion and Reperfusion in Rat Pial Circulation

(2015) Dominga Lapi et al.   MICROCIRCULATION

Role of Matrix Metalloproteinases in the Pathogenesis of Traumatic Brain Injury

(2015) P. M. Abdul-Muneer et al.   MOLECULAR NEUROBIOLOGY

Excess salt exacerbates blood-brain barrier disruption via a p38/MAPK/SGK1-dependent pathway in permanent cerebral ischemia

(2015) Tongshuai Zhang et al.   Scientific Reports

Recombinant Tissue Plasminogen Activator Enhances Microglial Cell Recruitment after Stroke in Mice

(2014) Sébastien Lenglet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Beneficial Effect of Melatonin in Brain Endothelial Cells against Oxygen-Glucose Deprivation Followed by Reperfusion-Induced Injury

(2014) Juhyun Song et al.   Oxidative Medicine and Cellular Longevity

Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal

(2014) S. Salzano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Post-ischemic inflammation regulates neural damage and protection

(2014) Takashi Shichita et al.   Frontiers in Cellular Neuroscience

Neuroprotection by Acetyl-11-Keto-β-Boswellic Acid, in Ischemic Brain Injury Involves the Nrf2/HO-1 defense Pathway

(2014) Yi Ding et al.   Scientific Reports

Peroxiredoxin 4 Protects Against Nonalcoholic Steatohepatitis and Type 2 Diabetes in a Nongenetic Mouse Model

(2013) Atsunori Nabeshima et al.   ANTIOXIDANTS & REDOX SIGNALING

The tension mounts: Stress fibers as force-generating mechanotransducers

(2013) Keith Burridge et al.   JOURNAL OF CELL BIOLOGY

Peroxiredoxin 4, A Novel Circulating Biomarker for Oxidative Stress and the Risk of Incident Cardiovascular Disease and All‐Cause Mortality

(2013) Ali Abbasi et al.   Journal of the American Heart Association

Transgenic Overexpression of Peroxiredoxin-2 Attenuates Ischemic Neuronal Injury Via Suppression of a Redox-Sensitive Pro-Death Signaling Pathway

(2012) Yu Gan et al.   ANTIOXIDANTS & REDOX SIGNALING

Free Radical Scavenger Edaravone Administration Protects against Tissue Plasminogen Activator Induced Oxidative Stress and Blood Brain Barrier Damage

(2012) Violeta Lukic-Panin et al.   CURRENT NEUROVASCULAR RESEARCH

Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain

(2012) Takashi Shichita et al.   NATURE MEDICINE

Peroxiredoxin sets the brain on fire after stroke

(2012) Lidia Garcia-Bonilla et al.   NATURE MEDICINE

The role of free radical generation in increasing cerebrovascular permeability

(2011) Paul A. Fraser   FREE RADICAL BIOLOGY AND MEDICINE

Rat pial microvascular responses to melatonin during bilateral common carotid artery occlusion and reperfusion

(2011) Dominga Lapi et al.   JOURNAL OF PINEAL RESEARCH

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Circulating Levels of Peroxiredoxin 4 as a Novel Biomarker of Oxidative Stress in Patients with Sepsis

(2011) Janin Schulte et al.   SHOCK

Distinct Effects of Tissue-Type Plasminogen Activator and SMTP-7 on Cerebrovascular Inflammation Following Thrombolytic Reperfusion

(2011) Takuro Miyazaki et al.   STROKE

Overexpression of Peroxiredoxin 4 Protects Against High-Dose Streptozotocin-Induced Diabetes by Suppressing Oxidative Stress and Cytokines in Transgenic Mice

(2010) Yan Ding et al.   ANTIOXIDANTS & REDOX SIGNALING

Immunoluminometric assay for quantification of peroxiredoxin 4 in human serum

(2010) Janin Schulte et al.   CLINICA CHIMICA ACTA

Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum

(2010) Timothy J Tavender et al.   EMBO JOURNAL

Peroxiredoxin IV protects cells from oxidative stress by removing H2O2 produced during disulphide formation

(2010) T. J. Tavender et al.   JOURNAL OF CELL SCIENCE

Matrix Metalloproteinase-9 Mediates Hypoxia-Induced Vascular Leakage in the Brain via Tight Junction Rearrangement

(2010) Alexander T Bauer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroinflammation and Neuroprotective Strategies in Acute Ischaemic Stroke - from bench to bedside

(2009) Imtiaz Shah et al.   CURRENT MOLECULAR MEDICINE

Typical 2-Cys peroxiredoxins - structures, mechanisms and functions

(2009) Andrea Hall et al.   FEBS Journal

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

Peroxiredoxin IV is an endoplasmic reticulum-localized enzyme forming oligomeric complexes in human cells

(2008) Timothy J. Tavender et al.   BIOCHEMICAL JOURNAL

Peroxiredoxin 4knockout results in elevated spermatogenic cell death via oxidative stress

(2008) Yoshihito Iuchi et al.   BIOCHEMICAL JOURNAL