Three functional variants in the NLRP3 gene are associated with susceptibility and clinical characteristics of systemic lupus erythematosus

Differential expression of the inflammasome complex genes in systemic lupus erythematosus

(2020) Heidi Lacerda Alves da Cruz et al.   IMMUNOGENETICS

Inflammasome activation and regulation: toward a better understanding of complex mechanisms

(2020) Danping Zheng et al.   Cell Discovery

Role of the NLRP3 inflammasome in autoimmune diseases

(2020) Zhe Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Association of nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 polymorphisms with systemic lupus erythematosus disease activity and biomarker levels

(2020) Zhenzhen Su et al.   MEDICINE

Immunological pathogenesis and treatment of systemic lupus erythematosus

(2019) Lu Pan et al.   World Journal of Pediatrics

NOD-like receptors and inflammasomes: A review of their canonical and non-canonical signaling pathways

(2019) Jaye M. Platnich et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Innate Immune Cells' Contribution to Systemic Lupus Erythematosus

(2019) Andrés A. Herrada et al.   Frontiers in Immunology

Cytokines in Inflammatory Disease

(2019) Shinwan Kany et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NLRP3: A promising therapeutic target for autoimmune diseases

(2018) Hui-Hui Shen et al.   AUTOIMMUNITY REVIEWS

Genetic association between the NLRP3 gene and acne vulgaris in a Chinese population

(2018) C. Shen et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Association of NLRP3 single nucleotide polymorphisms with ulcerative colitis: A case-control study

(2018) S. Hanaei et al.   Clinics and Research in Hepatology and Gastroenterology

Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus

(2018) Zhen-Zhen Ma et al.   Journal of Inflammation-London

Unravelling the Roles of Susceptibility Loci for Autoimmune Diseases in the Post-GWAS Era

(2018) Jody Ye et al.   Genes

Polymorphisms and expression of inflammasome genes are associated with the development and severity of rheumatoid arthritis in Brazilian patients

(2017) Catarina Addobbati et al.   INFLAMMATION RESEARCH

The association of NLRP3 and TNFRSF1A polymorphisms with risk of ankylosing spondylitis and treatment efficacy of etanercept

(2017) Shengchun Zhao et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective

(2017) Vaishali R. Moulton et al.   TRENDS IN MOLECULAR MEDICINE

Podocyte Activation of NLRP3 Inflammasomes Contributes to the Development of Proteinuria in Lupus Nephritis

(2017) Rong Fu et al.   Arthritis & Rheumatology

Associations of interactions between NLRP3 SNPs and HLA mismatch with acute and extensive chronic graft-versus-host diseases

(2017) Hidekazu Takahashi et al.   Scientific Reports

Comprehensive review of genetic association studies and meta-analysis on miRNA polymorphisms and rheumatoid arthritis and systemic lupus erythematosus susceptibility

(2016) Lingyu Fu et al.   HUMAN IMMUNOLOGY

Hyperactivation of the NLRP3 Inflammasome in Myeloid Cells Leads to Severe Organ Damage in Experimental Lupus

(2016) Ailing Lu et al.   JOURNAL OF IMMUNOLOGY

Anti-dsDNA antibodies bind to TLR4 and activate NLRP3 inflammasome in lupus monocytes/macrophages

(2016) Hui Zhang et al.   Journal of Translational Medicine

Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus

(2016) David L Morris et al.   NATURE GENETICS

NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis

(2016) Geena Paramel Varghese et al.   Journal of the American Heart Association

Immunogenetics of systemic lupus erythematosus: A comprehensive review

(2015) Yogita Ghodke-Puranik et al.   JOURNAL OF AUTOIMMUNITY

Genetic Variations in Pattern Recognition Receptor Loci Are Associated with Anti-TNF Response in Patients with Rheumatoid Arthritis

(2015) Jacob Sode et al.   PLoS One

Genetic Factors in Systemic Lupus Erythematosus: Contribution to Disease Phenotype

(2015) Fulvia Ceccarelli et al.   Journal of Immunology Research

Anti-TNF Treatment Response in Rheumatoid Arthritis Patients Is Associated with Genetic Variation in the NLRP3-Inflammasome

(2014) Jacob Sode et al.   PLoS One

Sex-dependent differential activation of NLRP3 and AIM2 inflammasomes in SLE macrophages

(2014) C.-A. Yang et al.   RHEUMATOLOGY

Neutrophil Extracellular Trap-Associated Protein Activation of the NLRP3 Inflammasome Is Enhanced in Lupus Macrophages

(2012) J. M. Kahlenberg et al.   JOURNAL OF IMMUNOLOGY

The genetics of lupus: a functional perspective

(2012) Sandra G Guerra et al.   ARTHRITIS RESEARCH & THERAPY

Role of the Inflammasome, IL-1β, and IL-18 in Bacterial Infections

(2011) Manoranjan Sahoo et al.   TheScientificWorldJOURNAL

Updating on the pathogenesis of systemic lupus erythematosus

(2010) R. Gualtierotti et al.   AUTOIMMUNITY REVIEWS

Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma

(2009) Yuki Hitomi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Recent Advances in the Genetics of Autoimmune Disease

(2008) Peter K. Gregersen et al.   Annual Review of Immunology

Active Caspase-1 Is a Regulator of Unconventional Protein Secretion

(2008) Martin Keller et al.   CELL

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

(2008) Alexandra-Chloé Villani et al.   NATURE GENETICS