Human B-cell memory is shaped by age- and tissue-specific T-independent and GC-dependent events

A Reassessment of IgM Memory Subsets in Humans

(2015) Davide Bagnara et al.   JOURNAL OF IMMUNOLOGY

Levels of somatic hypermutations in B cell receptors increase during childhood

(2014) E. J. H. Schatorjé et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Re-evaluation of the Immunological Big Bang

(2014) Martin F. Flajnik   CURRENT BIOLOGY

Clonal and cellular dynamics in germinal centers

(2014) Gabriel D Victora et al.   CURRENT OPINION IN IMMUNOLOGY

Generation of memory B cells inside and outside germinal centers

(2014) Toshitada Takemori et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Identification of a human splenic marginal zone B cell precursor with NOTCH2-dependent differentiation properties

(2014) Marc Descatoire et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CpG Drives Human Transitional B Cells to Terminal Differentiation and Production of Natural Antibodies

(2014) F. Capolunghi et al.   JOURNAL OF IMMUNOLOGY

The Majority of Human Memory B Cells Recognizing RhD and Tetanus Resides in IgM+ B Cells

(2014) L. Della Valle et al.   JOURNAL OF IMMUNOLOGY

Improving access to vaccines through tiered pricing

(2014) Seth Berkley   LANCET

CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype

(2014) Griselda V Zuccarino-Catania et al.   NATURE IMMUNOLOGY

Defects in Laterality with Emphasis on Heterotaxy Syndromes with Asplenia and Polysplenia: An Autopsy Case Series at a Single Institution

(2014) Elizabeth C. Burton et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

(2013) Florian Klein et al.   CELL

Preserved antibody levels and loss of memory B cells against pneumococcus and tetanus after splenectomy: Tailoring better vaccination strategies

(2013) M. Manuela Rosado et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Why do we need IgM memory B cells?

(2013) Federica Capolunghi et al.   IMMUNOLOGY LETTERS

Neonatal Follicular Th Cell Responses Are Impaired and Modulated by IL-4

(2013) I. Debock et al.   JOURNAL OF IMMUNOLOGY

Human Germline Antibody Gene Segments Encode Polyspecific Antibodies

(2013) Jordan R. Willis et al.   PLoS Computational Biology

Secondary mechanisms of diversification in the human antibody repertoire

(2013) Bryan S. Briney et al.   Frontiers in Immunology

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory

(2012) Tomohiro Kaji et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Innate Immune Functions of Macrophage Subpopulations in the Spleen

(2012) Joke M.M. den Haan et al.   Journal of Innate Immunity

Does DNA repair occur during somatic hypermutation?

(2012) Huseyin Saribasak et al.   SEMINARS IN IMMUNOLOGY

IL-21 is the primary common   chain-binding cytokine required for human B-cell differentiation in vivo

(2011) M. Recher et al.   BLOOD

Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways

(2011) M. A. Berkowska et al.   BLOOD

Switched memory B cells maintain specific memory independently of serum antibodies: The hepatitis B example

(2011) M. Manuela Rosado et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Biospecimen Reporting for Improved Study Quality (BRISQ)

(2011) Helen M. Moore et al.   JOURNAL OF PROTEOME RESEARCH

Post-splenectomy and hyposplenic states

(2011) Antonio Di Sabatino et al.   LANCET

Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response

(2011) K. A. Pape et al.   SCIENCE

High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

(2010) Y.-C. Wu et al.   BLOOD

TLR Ligation Triggers Somatic Hypermutation in Transitional B Cells Inducing the Generation of IgM Memory B Cells

(2010) A. Aranburu et al.   JOURNAL OF IMMUNOLOGY

Human Marginal Zone B Cells

(2009) Jean-Claude Weill et al.   Annual Review of Immunology

Molecular footprints of a germinal center derivation of human IgM+(IgD+)CD27+B cells and the dynamics of memory B cell generation

(2009) Marc Seifert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

From the fetal liver to spleen and gut: the highway to natural antibody

(2009) M M Rosado et al.   Mucosal Immunology

Multiple layers of B cell memory with different effector functions

(2009) Ismail Dogan et al.   NATURE IMMUNOLOGY

The human spleen is a major reservoir for long-lived vaccinia virus-specific memory B cells

(2008) M. Mamani-Matsuda et al.   BLOOD

Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting

(2008) N. S. Longo et al.   BLOOD

Evolution in miniature: selection, survival and distribution of antigen reactive cells in the germinal centre

(2008) David M Tarlinton   IMMUNOLOGY AND CELL BIOLOGY

Two levels of protection for the B cell genome during somatic hypermutation

(2008) Man Liu et al.   NATURE

Next-generation DNA sequencing

(2008) Jay Shendure et al.   NATURE BIOTECHNOLOGY

Heterosubtypic Neutralizing Monoclonal Antibodies Cross-Protective against H5N1 and H1N1 Recovered from Human IgM+ Memory B Cells

(2008) Mark Throsby et al.   PLoS One