NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus

The kinase activity of PKR represses inflammasome activity

(2016) Howard CH Yim et al.   CELL RESEARCH

The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells

(2015) John R. Lukens et al.   IMMUNITY

TLR9 is required for MAPK/NF-κB activation but does not cooperate with TLR2 or TLR6 to induce host resistance to Brucella abortus

(2015) Marco Túlio Gomes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mechanisms of inflammasome activation: recent advances and novel insights

(2015) Sivapriya K. Vanaja et al.   TRENDS IN CELL BIOLOGY

NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease

(2014) Roberta Caruso et al.   IMMUNITY

Central Role of MyD88-Dependent Dendritic Cell Maturation and Proinflammatory Cytokine Production to Control Brucella abortus Infection

(2014) G. C. Macedo et al.   JOURNAL OF IMMUNOLOGY

The multifaceted nature of NLRP12

(2014) Sinem Tuncer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Malaria-Induced NLRP12/NLRP3-Dependent Caspase-1 Activation Mediates Inflammation and Hypersensitivity to Bacterial Superinfection

(2014) Marco A. Ataide et al.   PLoS Pathogens

Reactive Oxygen Species Regulate Caspase-11 Expression and Activation of the Non-canonical NLRP3 Inflammasome during Enteric Pathogen Infection

(2014) Christopher R. Lupfer et al.   PLoS Pathogens

Toll-Like Receptor 6 Plays an Important Role in Host Innate Resistance to Brucella abortus Infection in Mice

(2013) Leonardo A. de Almeida et al.   INFECTION AND IMMUNITY

Caspase-1: The inflammasome and beyond

(2013) Gabriel Sollberger et al.   Innate Immunity

Critical Role of ASC Inflammasomes and Bacterial Type IV Secretion System in Caspase-1 Activation and Host Innate Resistance to Brucella abortus Infection

(2013) M. T. R. Gomes et al.   JOURNAL OF IMMUNOLOGY

Characterization of NLRP12 during the In Vivo Host Immune Response to Klebsiella pneumoniae and Mycobacterium tuberculosis

(2013) Irving C. Allen et al.   PLoS One

Lack of Endogenous IL-10 Enhances Production of Proinflammatory Cytokines and Leads to Brucella abortus Clearance in Mice

(2013) Patrícia P. Corsetti et al.   PLoS One

Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection

(2013) M. H. Zaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The NLRP12 Inflammasome Recognizes Yersinia pestis

(2012) Gregory I. Vladimer et al.   IMMUNITY

NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling

(2012) Irving C. Allen et al.   IMMUNITY

The noncanonical NF-κB pathway

(2012) Shao-Cong Sun   IMMUNOLOGICAL REVIEWS

In Situ Microscopy Analysis Reveals Local Innate Immune Response Developed around Brucella Infected Cells in Resistant and Susceptible Mice

(2012) Richard Copin et al.   PLoS Pathogens

The role of innate immune signals in immunity to Brucella abortus

(2012) Marco Túlio R. Gomes et al.   Frontiers in Cellular and Infection Microbiology

The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis

(2011) Md. Hasan Zaki et al.   CANCER CELL

Nucleotide-Binding Oligomerization Domain-1 and -2 Play No Role in ControllingBrucella abortusInfection in Mice

(2011) Fernanda S. Oliveira et al.   Clinical & Developmental Immunology

Host Susceptibility toBrucella abortusInfection Is More Pronounced in IFN-γknockout than IL-12/β2-Microglobulin Double-Deficient Mice

(2011) Ana Paula M. S. Brandão et al.   Clinical & Developmental Immunology

Brucellosis and type IV secretion

(2011) Maarten F de Jong et al.   Future Microbiology

Brucellosis at the animal/ecosystem/human interface at the beginning of the 21st century

(2011) J. Godfroid et al.   PREVENTIVE VETERINARY MEDICINE

Update on the role of innate immune receptors during Brucella abortus infection

(2011) Sérgio C. Oliveira et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

The changing Brucella ecology: novel reservoirs, new threats

(2010) Georgios Pappas   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Cutting Edge: NLRP12 Controls Dendritic and Myeloid Cell Migration To Affect Contact Hypersensitivity

(2010) J. C. Arthur et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Caspase-1 Independent IL-1  Production Is Critical for Host Resistance to Mycobacterium tuberculosis and Does Not Require TLR Signaling In Vivo

(2010) K. D. Mayer-Barber et al.   JOURNAL OF IMMUNOLOGY

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

(2009) Tilmann Bürckstümmer et al.   NATURE IMMUNOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

NOD-like receptors (NLRs): bona fide intracellular microbial sensors

(2008) Michael H Shaw et al.   CURRENT OPINION IN IMMUNOLOGY