The human brain acetylome reveals that decreased acetylation of mitochondrial proteins associates with Alzheimer's disease

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

(2020) Erik C. B. Johnson et al.   NATURE MEDICINE

DNA methylation and histone post-translational modification stability in post-mortem brain tissue

(2019) Jessica S. Jarmasz et al.   Clinical Epigenetics

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

(2019) D. Allan Butterfield et al.   NATURE REVIEWS NEUROSCIENCE

A Unifying Hypothesis for Alzheimer’s Disease: From Plaques to Neurodegeneration

(2019) Frances A. Edwards   TRENDS IN NEUROSCIENCES

First comprehensive analysis of lysine acetylation in Alvinocaris longirostris from the deep-sea hydrothermal vents

(2018) Min Hui et al.   BMC GENOMICS

Comprehensive analysis of the lysine acetylome and its potential regulatory roles in the virulence of Streptococcus pneumoniae

(2018) Yu-Tong Liu et al.   Journal of Proteomics

Acetylome in Human Fibroblasts From Parkinson's Disease Patients

(2018) Sokhna M. S. Yakhine-Diop et al.   Frontiers in Cellular Neuroscience

A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex

(2018) Sarah J. Marzi et al.   NATURE NEUROSCIENCE

SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain

(2018) Alpna Tyagi et al.   Scientific Reports

An acetylation–phosphorylation switch that regulates tau aggregation propensity and function

(2017) Yari Carlomagno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systematic Analysis of Lysine Acetylation in the Halophilic Archaeon Haloferax mediterranei

(2017) Jingfang Liu et al.   JOURNAL OF PROTEOME RESEARCH

Palmitate-induced lipotoxicity alters acetylation of multiple proteins in clonal β cells and human pancreatic islets

(2017) Federica Ciregia et al.   Scientific Reports

The world of protein acetylation

(2016) Adrian Drazic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines

(2015) Gary E. Gibson et al.   JOURNAL OF NEUROCHEMISTRY

Dissection of metabolic pathways in the Db/Db mouse model by integrative proteome and acetylome analysis

(2015) Soraya Hölper et al.   Molecular BioSystems

The Potential of Pathological Protein Fragmentation in Blood-Based Biomarker Development for Dementia – With Emphasis on Alzheimer’s Disease

(2015) Dilek Inekci et al.   Frontiers in Neurology

Understanding the acetylome: translating targeted proteomics into meaningful physiology

(2014) Andrew Philp et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation

(2014) Gopinath Sutendra et al.   CELL

Diabetes Induces Lysine Acetylation of Intermediary Metabolism Enzymes in the Kidney

(2014) H. Kosanam et al.   DIABETES

SIRT3 Deacetylates ATP Synthase F1 Complex Proteins in Response to Nutrient- and Exercise-Induced Stress

(2013) Athanassios Vassilopoulos et al.   ANTIOXIDANTS & REDOX SIGNALING

Sirtuin 3 (SIRT3) Protein Regulates Long-chain Acyl-CoA Dehydrogenase by Deacetylating Conserved Lysines Near the Active Site

(2013) Sivakama S. Bharathi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways

(2013) Jeongsoon Park et al.   MOLECULAR CELL

The Cardiac Acetyl-Lysine Proteome

(2013) D. Brian Foster et al.   PLoS One

Proteomic Analysis Reveals Differentially Regulated Protein Acetylation in Human Amyotrophic Lateral Sclerosis Spinal Cord

(2013) Dong Liu et al.   PLoS One

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

(2013) M. J. Rardin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

(2012) David J. Irwin et al.   BRAIN

Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism

(2012) Ruben Nogueiras et al.   PHYSIOLOGICAL REVIEWS

Proteomic Analysis of Lysine Acetylation Sites in Rat Tissues Reveals Organ Specificity and Subcellular Patterns

(2012) Alicia Lundby et al.   Cell Reports

The Fasted/Fed Mouse Metabolic Acetylome: N6-Acetylation Differences Suggest Acetylation Coordinates Organ-Specific Fuel Switching

(2011) Li Yang et al.   JOURNAL OF PROTEOME RESEARCH

Detection, Evaluation and Minimization of Nonenzymatic Deamidation in Proteomic Sample Preparation

(2011) Piliang Hao et al.   MOLECULAR & CELLULAR PROTEOMICS

Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase

(2011) J. Du et al.   SCIENCE

The acetylation of tau inhibits its function and promotes pathological tau aggregation

(2011) Todd J. Cohen et al.   Nature Communications

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux

(2010) Q. Wang et al.   SCIENCE

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Comprehensive lysine acetylomes emerging from bacteria to humans

(2010) Go-Woon Kim et al.   TRENDS IN BIOCHEMICAL SCIENCES

The neuropathology of probable Alzheimer disease and mild cognitive impairment

(2009) Julie A. Schneider et al.   ANNALS OF NEUROLOGY

Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria

(2009) Huseyin Cimen et al.   BIOCHEMISTRY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE