Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines

SIRT5 is under the control of PGC-1α and AMPK and is involved in regulation of mitochondrial energy metabolism

(2014) Marcin Buler et al.   FASEB JOURNAL

SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells

(2014) Ozkan Ozden et al.   FREE RADICAL BIOLOGY AND MEDICINE

Distinct Patterns of Sirtuin Expression During Progression of Alzheimer’s Disease

(2014) Mirjam I. Lutz et al.   NEUROMOLECULAR MEDICINE

SIRT5 desuccinylates and activates SOD1 to eliminate ROS

(2013) Zhi-Feng Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks

(2013) Matthew J. Rardin et al.   Cell Metabolism

Widespread and Enzyme-independentNϵ-Acetylation andNϵ-Succinylation of Proteins in the Chemical Conditions of the Mitochondrial Matrix

(2013) Gregory R. Wagner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways

(2013) Jeongsoon Park et al.   MOLECULAR CELL

Lysine Succinylation Is a Frequently Occurring Modification in Prokaryotes and Eukaryotes and Extensively Overlaps with Acetylation

(2013) Brian T. Weinert et al.   Cell Reports

Abnormal thiamine-dependent processes in Alzheimer's Disease. Lessons from diabetes

(2012) Gary E. Gibson et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

(2012) Alexander S. Hebert et al.   MOLECULAR CELL

Extramitochondrial tricarboxylic acid cycle in retinal rod outer segments

(2011) Isabella Panfoli et al.   BIOCHIMIE

Evaluation of Different Multidimensional LC–MS/MS Pipelines for Isobaric Tags for Relative and Absolute Quantitation (iTRAQ)-Based Proteomic Analysis of Potato Tubers in Response to Cold Storage

(2011) Yong Yang et al.   JOURNAL OF PROTEOME RESEARCH

Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation

(2011) Gary E. Gibson et al.   NEUROBIOLOGY OF AGING

Identification of lysine succinylation as a new post-translational modification

(2010) Zhihong Zhang et al.   Nature Chemical Biology

Novel functions of the α-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease

(2008) Qingli Shi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE