Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery
出版年份 2021 全文链接
标题
Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery
作者
关键词
-
出版物
JOURNAL OF MEDICINAL CHEMISTRY
Volume 64, Issue 9, Pages 5730-5745
出版商
American Chemical Society (ACS)
发表日期
2021-04-29
DOI
10.1021/acs.jmedchem.0c02207
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Nucleotide‐induced folding of cell division protein FtsZ from Staphylococcus aureus
- (2020) Sonia Huecas et al. FEBS Journal
- Antimicrobial Action and Reversal of Resistance in MRSA by Difluorobenzamide Derivatives Targeted at FtsZ
- (2020) Wern Chern Chai et al. Antibiotics-Basel
- Synthetic developmental regulator MciZ targets FtsZ across Bacillus species and inhibits bacterial division
- (2019) Lidia Araújo-Bazán et al. MOLECULAR MICROBIOLOGY
- A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia
- (2019) Nagore I. Marín-Ramos et al. JOURNAL OF MEDICINAL CHEMISTRY
- FtsZ as an Antibacterial Target: Status and Guidelines for Progressing This Avenue
- (2019) Kennardy D. Kusuma et al. ACS Infectious Diseases
- Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens
- (2019) Edgar Ferrer-González et al. Scientific Reports
- Can β-Lactam Antibiotics Be Resurrected to Combat MRSA?
- (2018) Timothy J. Foster TRENDS IN MICROBIOLOGY
- Peptidoglycan synthesis drives an FtsZ-treadmilling-independent step of cytokinesis
- (2018) João M. Monteiro et al. NATURE
- Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis
- (2018) Alessandro Cassini et al. LANCET INFECTIOUS DISEASES
- Identification of the key interactions in structural transition pathway of FtsZ from Staphylococcus aureus
- (2017) Junso Fujita et al. JOURNAL OF STRUCTURAL BIOLOGY
- GTPase activity–coupled treadmilling of the bacterial tubulin FtsZ organizes septal cell wall synthesis
- (2017) Xinxing Yang et al. SCIENCE
- Treadmilling by FtsZ filaments drives peptidoglycan synthesis and bacterial cell division
- (2017) Alexandre W. Bisson-Filho et al. SCIENCE
- The structural assembly switch of cell division protein FtsZ probed with fluorescent allosteric inhibitors
- (2017) Marta Artola et al. Chemical Science
- New application of tiplaxtinin as an effective FtsZ-targeting chemotype for an antimicrobial study
- (2017) Ning Sun et al. MedChemComm
- A Polymerization-Associated Structural Switch in FtsZ That Enables Treadmilling of Model Filaments
- (2017) James M. Wagstaff et al. mBio
- Combining the FtsZ-Targeting Prodrug TXA709 and the Cephalosporin Cefdinir Confers Synergy and Reduces the Frequency of Resistance in Methicillin-Resistant Staphylococcus aureus
- (2016) Malvika Kaul et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Cytological Profile of Antibacterial FtsZ Inhibitors and Synthetic Peptide MciZ
- (2016) Lidia Araújo-Bazán et al. Frontiers in Microbiology
- Synthesis and Biological Evaluation of Novel FtsZ-targeted 3-arylalkoxy-2,6-difluorobenzamides as Potential Antimicrobial Agents
- (2015) Shengsheng Qiang et al. Chemical Biology & Drug Design
- Resveratrol antibacterial activity against Escherichia coli is mediated by Z-ring formation inhibition via suppression of FtsZ expression
- (2015) Dahyun Hwang et al. Scientific Reports
- Effective GTP-Replacing FtsZ Inhibitors and Antibacterial Mechanism of Action
- (2014) Marta Artola et al. ACS Chemical Biology
- Bacterial cell division proteins as antibiotic targets
- (2014) Tanneke den Blaauwen et al. BIOORGANIC CHEMISTRY
- Understanding Nucleotide-Regulated FtsZ Filament Dynamics and the Monomer Assembly Switch with Large-Scale Atomistic Simulations
- (2014) Erney Ramírez-Aportela et al. BIOPHYSICAL JOURNAL
- Synthetic Inhibitors of Bacterial Cell Division Targeting the GTP-Binding Site of FtsZ
- (2013) Laura B. Ruiz-Avila et al. ACS Chemical Biology
- Plumbagin inhibits cytokinesis inBacillus subtilisby inhibiting FtsZ assembly - a mechanistic study of its antibacterial activity
- (2013) Anusri Bhattacharya et al. FEBS Journal
- Structural Change in FtsZ Induced by Intermolecular Interactions between Bound GTP and the T7 Loop
- (2013) Takashi Matsui et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Comparison of Small Molecule Inhibitors of the Bacterial Cell Division Protein FtsZ and Identification of a Reliable Cross-Species Inhibitor
- (2012) David E. Anderson et al. ACS Chemical Biology
- Structural reorganization of the bacterial cell-division protein FtsZ fromStaphylococcus aureus
- (2012) Takashi Matsui et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Mechanism of Action of the Cell-Division Inhibitor PC190723: Modulation of FtsZ Assembly Cooperativity
- (2012) Nathaniel L. Elsen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Restoring Methicillin-Resistant Staphylococcus aureus Susceptibility to -Lactam Antibiotics
- (2012) C. M. Tan et al. Science Translational Medicine
- Targeting the Assembly of Bacterial Cell Division Protein FtsZ with Small Molecules
- (2011) Claudia Schaffner-Barbero et al. ACS Chemical Biology
- Overview of theCCP4 suite and current developments
- (2011) Martyn D. Winn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Multiple effects of benzamide antibiotics on FtsZ function
- (2011) David W. Adams et al. MOLECULAR MICROBIOLOGY
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Insights into Nucleotide Recognition by Cell Division Protein FtsZ from amant-GTP Competition Assay and Molecular Dynamics
- (2010) Claudia Schaffner-Barbero et al. BIOCHEMISTRY
- The Antibacterial Cell Division Inhibitor PC190723 Is an FtsZ Polymer-stabilizing Agent That Induces Filament Assembly and Condensation
- (2010) José M. Andreu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Allosteric Models for Cooperative Polymerization of Linear Polymers
- (2008) Emily R. Miraldi et al. BIOPHYSICAL JOURNAL
- Investigation of Regulation of FtsZ Assembly by SulA and Development of a Model for FtsZ Polymerization
- (2008) A. Dajkovic et al. JOURNAL OF BACTERIOLOGY
- Cell-division inhibitors: new insights for future antibiotics
- (2008) Rowena L. Lock et al. NATURE REVIEWS DRUG DISCOVERY
- An Inhibitor of FtsZ with Potent and Selective Anti-Staphylococcal Activity
- (2008) D. J. Haydon et al. SCIENCE
- Energetics and Geometry of FtsZ Polymers: Nucleated Self-Assembly of Single Protofilaments
- (2007) Sonia Huecas et al. BIOPHYSICAL JOURNAL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search