Pyridine‐2( 1 H )‐thiones: Versatile precursors for one‐pot synthesis of new nicotinonitrile‐thiazole hybrids

Bis(benzofuran-enaminone) hybrid possessing piperazine linker: Versatile precursor for microwave assisted synthesis of bis(pyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidines)

(2021) Ahmed E. M. Mekky et al.   SYNTHETIC COMMUNICATIONS

Synthesis, in‐vitro and in‐silico study of novel thiazoles as potent antibacterial agents and MurB inhibitors

(2020) Sherif M. H. Sanad et al.   ARCHIV DER PHARMAZIE

Synthesis and antioxidant assay of new nicotinonitrile analogues clubbed thiazole, pyrazole and/or pyridine ring systems

(2020) Hana M.A. Abumelha   JOURNAL OF HETEROCYCLIC CHEMISTRY

Facile synthesis and characterization of novel benzo-fused macrocyclic dicarbonitriles and pyrazolo-fused macrocycles containing thiazole subunits

(2020) Ahmed A. M. Ahmed et al.   SYNTHETIC COMMUNICATIONS

Synthesis, in-vitro antibacterial and anticancer screening of novel nicotinonitrile-coumarin hybrids utilizing piperazine citrate

(2020) Sherif M. H. Sanad et al.   SYNTHETIC COMMUNICATIONS

Synthesis, cytotoxicity and in vitro antibacterial screening of novel hydrazones bearing thienopyridine moiety as potent COX-2 inhibitors

(2020) Sherif M. H. Sanad et al.   Journal of the Iranian Chemical Society

Synthesis, cytotoxicity, in-vitro antibacterial screening and in-silico study of novel thieno[2,3-b]pyridines as potential pim-1 inhibitors

(2020) Ahmed E. M. Mekky et al.   SYNTHETIC COMMUNICATIONS

Novel Nicotinonitriles and Thieno[2,3‐ b ]pyridines as Potent Biofilm and COX‐2 Inhibitors: Synthesis, In Vitro and In Silico Studies

(2020) Sherif M. H. Sanad et al.   ChemistrySelect

Novel bis(pyrazole-benzofuran) hybrids possessing piperazine linker: Synthesis of potent bacterial biofilm and MurB inhibitors

(2020) Ahmed E.M. Mekky et al.   BIOORGANIC CHEMISTRY

Synthesis and in vitro study of new coumarin derivatives linked to nicotinonitrile moieties as potential acetylcholinesterase inhibitors

(2020) Ahmed E. M. Mekky et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Microwave‐Assisted Synthesis of Novel Bis(thiazoles) Incorporating Piperazine Moiety

(2019) Ahmed E. M. Mekky et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Cytotoxic Effects of Newly Synthesized Heterocyclic Candidates Containing Nicotinonitrile and Pyrazole Moieties on Hepatocellular and Cervical Carcinomas

(2019) Amira A. El-Sayed et al.   MOLECULES

Synthesis of novel bis(chromenes) and bis(chromeno[3,4-C]pyridine) incorporating piperazine moiety

(2019) Ahmed E. M. Mekky et al.   SYNTHETIC COMMUNICATIONS

Regioselective synthesis of novel antibacterial pyrazole-benzofuran hybrids: 2D NMR spectroscopy studies and molecular docking

(2019) Sherif M.H. Sanad et al.   JOURNAL OF MOLECULAR STRUCTURE

Microwave Assisted Three Component One‐pot Synthesis of Bis(aminoazolo[1,5‐ a ]pyrimidines) and Bis(aminoazino[1,2‐ a ]benzimidazoles) Bearing Thiazole Moiety

(2019) Ahmed E. M. Mekky et al.   ChemistrySelect

Novel Nicotinonitrile Derivatives Bearing Imino Moieties Enhance Apoptosis and Inhibit Tyrosine Kinase

(2018) Maher Elhashash et al.   Anti-Cancer Agents in Medicinal Chemistry

New Benzothiazole-based Thiazolidinones as Potent Antimicrobial Agents. Design, synthesis and Biological Evaluation

(2018) Michelyne Haroun et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Synthesis of Novel Bis[(5-cyanopyridin-6-yl)sulfanyl]butanes, Bis(2-S -alkylpyridines), and Bis(3-aminothieno[2,3-b ]pyridines) Incorporating 2,6-Dibromophenoxy Moiety

(2018) Sherif M. H. Sanad et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

A facile and expedient microwave-assisted solvent-free method for the synthesis of 2-amino-4-(2-oxo-2H-chromen-3-yl)nicotinonitriles

(2018) Devulapally Srikrishna et al.   Journal of the Iranian Chemical Society

Microwave-Assisted Synthesis of some Novel Azoles and Azolopyrimidines as Antimicrobial Agents

(2017) Sobhi Gomha et al.   MOLECULES

Synthesis of Some New 1,3,4-Thiadiazole, Thiazole and Pyridine Derivatives Containing 1,2,3-Triazole Moiety

(2017) Nadia Abdelriheem et al.   MOLECULES

Thiazole-Based Thiazolidinones as Potent Antimicrobial Agents. Design, Synthesis and Biological Evaluation

(2016) Michelyne Haroun et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Design, Synthesis, Antimicrobial Evaluation and Molecular Modeling Study of 1,2,4-Triazole-Based 4-Thiazolidinones

(2016) Sahar Ahmed et al.   MOLECULES

Synthesis of New 3-Heteroarylindoles as Potential Anticancer Agents

(2016) Abdou Abdelhamid et al.   MOLECULES

Orally Active 7-Substituted (4-Benzylphthalazin-1-yl)-2-methylpiperazin-1-yl]nicotinonitriles as Active-Site Inhibitors of Sphingosine 1-Phosphate Lyase for the Treatment of Multiple Sclerosis

(2014) Sven Weiler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 4-aryl-6-indolylpyridine-3-carbonitriles and evaluation of their antiproliferative activity

(2014) Naglaa Salem El-Sayed et al.   TETRAHEDRON LETTERS

Sodium fluoride as an efficient catalyst for the synthesis of 2,4-disubstituted-1,3-thiazoles and selenazoles at ambient temperature

(2013) Janardhan Banothu et al.   CHINESE CHEMICAL LETTERS

Synthesis, physicochemical characterization, cytotoxicity, antimicrobial, anti-inflammatory and psychotropic activity of new N-[1,3-(benzo)thiazol-2-yl]-ω-[3,4-dihydroisoquinolin-2(1H)-yl]alkanamides

(2013) Alla Zablotskaya et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Unsymmetrical Methylenebisphenol Derivatives

(2013) Samuel Guieu et al.   SYNLETT

Antimicrobial activity of thiazolyl benzenesulfonamide-condensed 2,4-thiazolidinediones derivatives

(2012) Nikhil M. Parekh et al.   MEDICINAL CHEMISTRY RESEARCH

Anticonvulsant Activity of a Combined Pharmacophore of Pyrazolo-pyridines with Lesser Toxicity in Mice

(2011) Nadeem Siddiqui et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Inhibitors of the RET tyrosine kinase based on a 2-(alkylsulfanyl)-4-(3-thienyl)nicotinonitrile scaffold

(2010) Wiebke Brandt et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Reactions of Some Novel Nicotinonitrile, Thiazolotriazole, and Imidazolotriazole Derivatives for Antioxidant Evaluation

(2010) Hayam H. Sayed et al.   SYNTHETIC COMMUNICATIONS

Synthesis and anticancer activity of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and N-bis(trifluoromethyl)alkyl-N′-benzothiazolyl ureas

(2009) Elena L. Luzina et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New pyridone, thioxopyridine, pyrazolopyridine and pyridine derivatives that modulate inflammatory mediators in stimulated RAW 264.7 murine macrophage

(2009) Nehal A. Hamdy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antimicrobial activities of some new thiazole and pyrazole derivatives based on 4,5,6,7-tetrahydrobenzothiophene moiety

(2009) M.A. Gouda et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 4-benzyl-1,3-thiazole derivatives as potential anti-inflammatory agents: An analogue-based drug design approach

(2009) Ritesh N. Sharma et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Design and synthesis of some thiazolyl and thiadiazolyl derivatives of antipyrine as potential non-acidic anti-inflammatory, analgesic and antimicrobial agents

(2008) Sherif A.F. Rostom et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis and characterization of novel 2-(2,4-disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one derivatives as inhibitors of NF-κB and AP-1 mediated transcription activation and as potential anti-inflammatory agents

(2008) Rajan S. Giri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2-Amino-6-furan-2-yl-4-substituted Nicotinonitriles as A2AAdenosine Receptor Antagonists

(2008) Monica Mantri et al.   JOURNAL OF MEDICINAL CHEMISTRY