Nanobubbles Containing sPD-1 and Ce6 Mediate Combination Immunotherapy and Suppress Hepatocellular Carcinoma in Mice

Challenges of combination therapy with immune checkpoint inhibitors for hepatocellular carcinoma

(2020) Ann-Lii Cheng et al.   JOURNAL OF HEPATOLOGY

Ultrasound-Mediated Co-Delivery of miR-34a and sPD-1 Complexed with Microbubbles for Synergistic Cancer Therapy

(2020) Yu-e Qin et al.   Cancer Management and Research

Modulation of Tumor Hypoxia by pH-Responsive Liposomes to Inhibit Mitochondrial Respiration for Enhancing Sonodynamic Therapy

(2020) Nan Zhang et al.   International Journal of Nanomedicine

Enhanced Cellular Uptake and Gene Silencing Activity of Survivin-siRNA via Ultrasound-Mediated Nanobubbles in Lung Cancer Cells

(2020) Hasan Akbaba et al.   PHARMACEUTICAL RESEARCH

Ultrasound targeting of microbubble-bound anti PD-L1 mAb to enhance anti-tumor effect of cisplatin in cervical cancer xenografts treatment

(2020) Yao Ma et al.   LIFE SCIENCES

Synergistic anti-tumor effect of paclitaxel and miR-34a combined with ultrasound microbubbles on cervical cancer in vivo and in vitro

(2019) J. Yu et al.   Clinical & Translational Oncology

Checkpoint blockade and nanosonosensitizer-augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice

(2019) Wenwen Yue et al.   Nature Communications

Gelatin–chlorin e6 conjugate for in vivo photodynamic therapy

(2019) Jihwan Son et al.   JOURNAL OF NANOBIOTECHNOLOGY

High Affinity of Chlorin e6 to Immunoglobulin G for Intraoperative Fluorescence Image-Guided Cancer Photodynamic and Checkpoint Blockade Therapy

(2019) Jiaojiao Xu et al.   ACS Nano

Meta-analysis of the efficacy and safety of PD-1/PD-L1 inhibitors administered alone or in combination with anti-VEGF agents in advanced hepatocellular carcinoma

(2019) Zhichao Feng et al.   GUT

Seeing the Invisible—Ultrasound Molecular Imaging

(2019) Alexandra Kosareva et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Enhanced Immunotherapy Based on Photodynamic Therapy for Both Primary and Lung Metastasis Tumor Eradication

(2018) Wen Song et al.   ACS Nano

Sonodynamic therapy-assisted immunotherapy: A novel modality for cancer treatment

(2018) Qianyu Zhang et al.   CANCER SCIENCE

Expression and clinical significance of PD‑1 in hepatocellular carcinoma tissues detected by a novel mouse anti-human PD‑1 monoclonal antibody

(2018) Ziwei Li et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Hypoxia-specific therapeutic agents delivery nanotheranostics: A sequential strategy for ultrasound mediated on-demand tritherapies and imaging of cancer

(2018) Qianhua Feng et al.   JOURNAL OF CONTROLLED RELEASE

Development of Ultrasound Theranostics for Cancer

(2018) Ryo Suzuki et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Ultrasound-targeted Photodynamic and Gene Dual Therapy for Effectively Inhibiting Triple Negative Breast Cancer by Cationic Porphyrin Lipid Microbubbles Loading with HIF1α-siRNA

(2018) shumin wang et al.   Nanoscale

The Antitumor Activity of Combinations of Cytotoxic Chemotherapy and Immune Checkpoint Inhibitors Is Model-Dependent

(2018) Chloé Grasselly et al.   Frontiers in Immunology

Ultrasound triggered phase-change nanodroplets for doxorubicin prodrug delivery and ultrasound diagnosis: An in vitro study

(2018) Jinbiao Gao et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Mechanical and Biological Effects of Ultrasound: A Review of Present Knowledge

(2017) Zahra Izadifar et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response?

(2017) Zijun Y. Xu-Monette et al.   Frontiers in Immunology

Radiation and checkpoint blockade immunotherapy: radiosensitisation and potential mechanisms of synergy

(2015) Andrew B Sharabi et al.   LANCET ONCOLOGY

Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturation

(2015) Wei Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-metastatic and pro-apoptotic effects elicited by combination photodynamic therapy with sonodynamic therapy on breast cancer both in vitro and in vivo

(2015) Pan Wang et al.   ULTRASONICS SONOCHEMISTRY

Targeted Antiangiogenesis Gene Therapy Using Targeted Cationic Microbubbles Conjugated with CD105 Antibody Compared with Untargeted Cationic and Neutral Microbubbles

(2015) Yu Zhou et al.   Theranostics

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Role of dendritic cells in the regulation of antitumor immunity

(2013) Nathalie Wathelet et al.   OncoImmunology

The tumor affinity of chlorin e6 and its sonodynamic effects on non-small cell lung cancer

(2012) Bei Chen et al.   ULTRASONICS SONOCHEMISTRY

Pharmacokinetic study of a novel sonosensitizer chlorin-e6 and its sonodynamic anti-cancer activity in hepatoma-22 tumor-bearing mice

(2011) Haitao Shi et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Sonodynamically induced anti-tumor effect with protoporphyrin IX on hepatoma-22 solid tumor

(2010) Xiaobing Wang et al.   ULTRASONICS

The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death

(2008) T Panaretakis et al.   CELL DEATH AND DIFFERENTIATION