The Role of JAK/STAT Molecular Pathway in Vascular Remodeling Associated with Pulmonary Hypertension
出版年份 2021 全文链接
标题
The Role of JAK/STAT Molecular Pathway in Vascular Remodeling Associated with Pulmonary Hypertension
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 9, Pages 4980
出版商
MDPI AG
发表日期
2021-05-07
DOI
10.3390/ijms22094980
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Endothelial Dysfunction in Pulmonary Hypertension: Cause or Consequence?
- (2021) Kondababu Kurakula et al. Biomedicines
- Blockade of JAK2 protects mice against hypoxia‐induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation
- (2020) Lei Zhang et al. CELL PROLIFERATION
- JAK Inhibition as a New Treatment Strategy for Patients with COVID-19
- (2020) Farhad Seif et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Targeting Jak-Stat Signaling in Experimental Pulmonary Hypertension
- (2020) Dinesh Yerabolu et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Interleukin-11 signaling underlies fibrosis, parenchymal dysfunction, and chronic inflammation of the airway
- (2020) Benjamin Ng et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Platelet-derived growth factor up-regulates Ca2+-sensing receptors in idiopathic pulmonary arterial hypertension
- (2019) Aya Yamamura et al. FASEB JOURNAL
- Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
- (2019) Camilla Udjus et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Injury-Induced Shedding of Extracellular Vesicles Depletes Endothelial Cells of Cav-1 (Caveolin-1) and Enables TGF-β (Transforming Growth Factor-β)–Dependent Pulmonary Arterial Hypertension
- (2019) Suellen D.S. Oliveira et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Is there a role for prostanoid-mediated inhibition of IL-6 trans-signalling in the management of pulmonary arterial hypertension?
- (2019) Gillian A. Durham et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Nintedanib ameliorates experimental pulmonary arterial hypertension via inhibition of endothelial mesenchymal transition and smooth muscle cell proliferation
- (2019) Takeo Tsutsumi et al. PLoS One
- VEGF and FGF-2: Promising targets for the treatment of respiratory disorders
- (2019) Ankit P. Laddha et al. RESPIRATORY MEDICINE
- Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
- (2019) Benjamin Ng et al. Science Translational Medicine
- Myelofibrosis in 2019: moving beyond JAK2 inhibition
- (2019) Michael Schieber et al. Blood Cancer Journal
- Kinases as potential targets for treatment of pulmonary hypertension and right ventricular dysfunction
- (2019) A. Weiss et al. BRITISH JOURNAL OF PHARMACOLOGY
- Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
- (2019) Liu et al. Cells
- Long-term Effects of the Janus Kinase 1/2 Inhibitor Ruxolitinib on Pulmonary Hypertension and the Cardiac Function in a Patient with Myelofibrosis
- (2019) Hiroshi Miyawaki et al. INTERNAL MEDICINE
- Isolation and characterization of endothelial-to-mesenchymal transition cells in pulmonary arterial hypertension
- (2018) Toshio Suzuki et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Inhibition of PDGF-BB-induced proliferation and migration in VSMCs by proanthocyanidin A2: Involvement of KDR and Jak-2/STAT-3/cPLA 2 signaling pathways
- (2018) Liudi Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- JAK2 mediates lung fibrosis, pulmonary vascular remodelling and hypertension in idiopathic pulmonary fibrosis: an experimental study
- (2018) Javier Milara et al. THORAX
- Haemodynamic definitions and updated clinical classification of pulmonary hypertension
- (2018) Gérald Simonneau et al. EUROPEAN RESPIRATORY JOURNAL
- Pulmonary Hypertension Exacerbated by Nintedanib Administration for Idiopathic Pulmonary Fibrosis
- (2018) Iwao Shimomura et al. INTERNAL MEDICINE
- IL11 is a crucial determinant of cardiovascular fibrosis
- (2017) Sebastian Schafer et al. NATURE
- Inhibition of JAK-STAT Signaling Suppresses Pathogenic Immune Responses in Medium and Large Vessel Vasculitis
- (2017) Hui Zhang et al. CIRCULATION
- In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target SlugCLINICAL PERSPECTIVE
- (2016) Rachel K. Hopper et al. CIRCULATION
- Clinical and prognostic value of endothelin-1 and big endothelin-1 expression in children with pulmonary hypertension
- (2016) Heiner Latus et al. HEART
- Grape seed procyanidin extract attenuates hypoxic pulmonary hypertension by inhibiting oxidative stress and pulmonary arterial smooth muscle cells proliferation
- (2016) Haifeng Jin et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes
- (2015) Steven C. Pugliese et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension
- (2015) B. Ranchoux et al. CIRCULATION
- 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
- (2015) Nazzareno Galiè et al. EUROPEAN RESPIRATORY JOURNAL
- Molecular Characterization of Reactive Oxygen Species in Systemic and Pulmonary Hypertension
- (2014) L. Zuo et al. AMERICAN JOURNAL OF HYPERTENSION
- Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis
- (2014) Yun Zhang et al. ANNALS OF THE RHEUMATIC DISEASES
- Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension
- (2014) Marlene Rabinovitch et al. CIRCULATION RESEARCH
- Pulmonary hypertension associated with chronic obstructive lung disease and idiopathic pulmonary fibrosis
- (2014) Yochai Adir et al. CURRENT OPINION IN PULMONARY MEDICINE
- Ruxolitinib leads to improvement of pulmonary hypertension in patients with myelofibrosis
- (2014) A Tabarroki et al. LEUKEMIA
- Molecular interactions of serotonin (5-HT) and endothelin-1 in vascular smooth muscle cells: in vitro and ex vivo analyses
- (2013) Subha Bhaskaran et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Protective Role of IL-6 in Vascular Remodeling inSchistosomaPulmonary Hypertension
- (2013) Brian B. Graham et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- NADPH Oxidases in Vascular Pathology
- (2013) Anna Konior et al. ANTIOXIDANTS & REDOX SIGNALING
- Transforming growth factor beta1 (TGFbeta1) in physiology and pathology
- (2013) Dariusz Kajdaniuk et al. Endokrynologia Polska
- Updated Clinical Classification of Pulmonary Hypertension
- (2013) Gerald Simonneau et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Reactive oxygen species as therapeutic targets in pulmonary hypertension
- (2013) Véronique Freund-Michel et al. Therapeutic Advances in Respiratory Disease
- NADPH oxidase-derived ROS and the regulation of pulmonary vessel tone
- (2012) G. Frazziano et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines
- (2012) Rachel J. Davies et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Dysregulated Renin–Angiotensin–Aldosterone System Contributes to Pulmonary Arterial Hypertension
- (2012) Frances S. de Man et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Dehydroepiandrosterone (DHEA) improves pulmonary hypertension in chronic obstructive pulmonary disease (COPD): A pilot study
- (2012) Eric Dumas de La Roque et al. ANNALES D ENDOCRINOLOGIE
- Inflammation in Pulmonary Arterial Hypertension
- (2012) Laura C. Price et al. CHEST
- Plasma aldosterone levels are elevated in patients with pulmonary arterial hypertension in the absence of left ventricular heart failure: a pilot study
- (2012) Bradley A. Maron et al. EUROPEAN JOURNAL OF HEART FAILURE
- Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH
- (2012) Audrey Courboulin et al. EUROPEAN RESPIRATORY JOURNAL
- Reactive oxygen and nitrogen species in pulmonary hypertension
- (2012) Diana M. Tabima et al. FREE RADICAL BIOLOGY AND MEDICINE
- A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis
- (2012) Srdan Verstovsek et al. NEW ENGLAND JOURNAL OF MEDICINE
- JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
- (2012) Claire Harrison et al. NEW ENGLAND JOURNAL OF MEDICINE
- Plexiform Lesions in Pulmonary Arterial Hypertension
- (2011) Danny Jonigk et al. AMERICAN JOURNAL OF PATHOLOGY
- Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension
- (2011) Roxane Paulin et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Angiotensin II utilizes Janus kinase 2 in hypertension, but not in the physiological control of blood pressure, during low-salt intake
- (2011) Amy K. L. Banes-Berceli et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Nuclear JAK2: Form and Function in Cancer
- (2011) Cui-Juan Qian et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Signal Transducers and Activators of Transcription-3/Pim1 Axis Plays a Critical Role in the Pathogenesis of Human Pulmonary Arterial Hypertension
- (2011) Roxane Paulin et al. CIRCULATION
- JAKs go nuclear: Emerging role of nuclear JAK1 and JAK2 in gene expression and cell growth
- (2011) Fouad A. Zouein et al. GROWTH FACTORS
- Role for miR-204 in human pulmonary arterial hypertension
- (2011) Audrey Courboulin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension
- (2010) Elaine Soon et al. CIRCULATION
- Circulating angiopoietins in idiopathic pulmonary arterial hypertension
- (2010) Philipp Kümpers et al. EUROPEAN HEART JOURNAL
- NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets
- (2009) Kathleen E. Dennis et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- CREB-Mediated IL-6 Expression Is Required for 15(S)-Hydroxyeicosatetraenoic Acid–Induced Vascular Smooth Muscle Cell Migration
- (2009) Koteswara R. Chava et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Altered Bone Morphogenetic Protein and Transforming Growth Factor-β Signaling in Rat Models of Pulmonary Hypertension
- (2009) Lu Long et al. CIRCULATION
- Endothelin-1 Impairs Nitric Oxide Signaling in Endothelial Cells Through a Protein Kinase Cδ-Dependent Activation of STAT3 and Decreased Endothelial Nitric Oxide Synthase Expression
- (2009) Neetu Sud et al. DNA AND CELL BIOLOGY
- Therapeutic potential of JAK2 inhibitors
- (2009) S. Verstovsek Hematology-American Society of Hematology Education Program
- Platelet-derived Growth Factor Expression and Function in Idiopathic Pulmonary Arterial Hypertension
- (2008) Frédéric Perros et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Clinical Outcomes of Pulmonary Arterial Hypertension in Carriers ofBMPR2Mutation
- (2008) Benjamin Sztrymf et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Role of platelet-derived growth factors in physiology and medicine
- (2008) J. Andrae et al. GENES & DEVELOPMENT
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started