Dual Specificity Kinase DYRK3 Promotes Aggressiveness of Glioblastoma by Altering Mitochondrial Morphology and Function

Advances in the Knowledge of the Molecular Biology of Glioblastoma and Its Impact in Patient Diagnosis, Stratification, and Treatment

(2020) Belén Delgado‐Martín et al.   Advanced Science

Higher levels of dynamin-related protein 1 are associated with reduced radiation sensitivity of glioblastoma cells

(2020) Wen-Yu Cheng et al.   CURRENT NEUROVASCULAR RESEARCH

The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities

(2020) Jacopo Boni et al.   Cancers

Therapeutic potential of targeting mitochondrial dynamics in cancer

(2020) Tiago Rodrigues et al.   BIOCHEMICAL PHARMACOLOGY

Dyrk3 loss activates the purine metabolism and promotes hepatocellular carcinoma progression

(2019) Fei Ma et al.   HEPATOLOGY

Mitochondrial Dynamics: Biogenesis, Fission, Fusion, and Mitophagy in the Regulation of Stem Cell Behaviors

(2019) Wenyan Fu et al.   Stem Cells International

Harmine suppresses the proliferation of pancreatic cancer cells and sensitizes pancreatic cancer to gemcitabine treatment

(2019) Lin-wen Wu et al.   OncoTargets and Therapy

Decreased FBP1 expression rewires metabolic processes affecting aggressiveness of glioblastoma

(2019) Beomseok Son et al.   ONCOGENE

Mitochondrial dynamics: overview of molecular mechanisms

(2018) Lisa Tilokani et al.   Essays in Biochemistry

Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer

(2018) Subhamoy Dasgupta et al.   NATURE

LDR-Induced miR-30a and miR-30b Target the PAI-1 Pathway to Control Adverse Effects of NSCLC Radiotherapy

(2018) Gaeul Park et al.   MOLECULAR THERAPY

Dyrk1B overexpression is associated with breast cancer growth and a poor prognosis

(2017) Yingying Chen et al.   HUMAN PATHOLOGY

mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1

(2017) Masahiro Morita et al.   MOLECULAR CELL

Tbx2 confers poor prognosis in glioblastoma and promotes temozolomide resistance with change of mitochondrial dynamics

(2017) Fuxin Yi et al.   OncoTargets and Therapy

TFAP2C promotes lung tumorigenesis and aggressiveness through miR-183- and miR-33a-mediated cell cycle regulation

(2016) J Kang et al.   ONCOGENE

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Oncogenic regulation of tumor metabolic reprogramming

(2016) Míriam Tarrado-Castellarnau et al.   Oncotarget

Mitochondrial Mechanisms of Metabolic Reprogramming in Proliferating Cells

(2015) Maria Sousa et al.   CURRENT MEDICINAL CHEMISTRY

3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties

(2015) Céline Meinguet et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Durability of Kinase-Directed Therapies--A Network Perspective on Response and Resistance

(2015) B. W. Murray et al.   MOLECULAR CANCER THERAPEUTICS

Mitochondrial Division Is Requisite to RAS-Induced Transformation and Targeted by Oncogenic MAPK Pathway Inhibitors

(2015) Madhavika N. Serasinghe et al.   MOLECULAR CELL

Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

Mitochondrial control by DRP1 in brain tumor initiating cells

(2015) Qi Xie et al.   NATURE NEUROSCIENCE

Phosphatidylinositol 3-kinase/Akt signaling as a key mediator of tumor cell responsiveness to radiation

(2015) Mahmoud Toulany et al.   SEMINARS IN CANCER BIOLOGY

DYRK2 regulates epithelial-mesenchymal-transition and chemosensitivity through Snail degradation in ovarian serous adenocarcinoma

(2015) Noriko Yamaguchi et al.   TUMOR BIOLOGY

Mitochondrial Dynamics Protein Drp1 Is Overexpressed in Oncocytic Thyroid Tumors and Regulates Cancer Cell Migration

(2015) André Ferreira-da-Silva et al.   PLoS One

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Involvement of Drp1 in hypoxia-induced migration of human glioblastoma U251 cells

(2014) YU-YING WAN et al.   ONCOLOGY REPORTS

Tumor Suppressor DYRK1A Effects on Proliferation and Chemoresistance of AML Cells by Downregulating c-Myc

(2014) Qiang Liu et al.   PLoS One

Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines

(2014) Joshua C. Anderson et al.   RADIOTHERAPY AND ONCOLOGY

DYRK2 controls the epithelial–mesenchymal transition in breast cancer by degrading Snail

(2013) Rei Mimoto et al.   CANCER LETTERS

The DREAM Complex Mediates GIST Cell Quiescence and Is a Novel Therapeutic Target to Enhance Imatinib-Induced Apoptosis

(2013) S. Boichuk et al.   CANCER RESEARCH

Dual Specificity Kinase DYRK3 Couples Stress Granule Condensation/Dissolution to mTORC1 Signaling

(2013) Frank Wippich et al.   CELL

Dosage of Dyrk1a Shifts Cells within a p21-Cyclin D1 Signaling Map to Control the Decision to Enter the Cell Cycle

(2013) Jia-Yun Chen et al.   MOLECULAR CELL

Dyrk kinases regulate phosphorylation of doublecortin, cytoskeletal organization, and neuronal morphology

(2012) Tatiana I. Slepak et al.   Cytoskeleton

DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells

(2012) Naoe Taira et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial dynamics regulates migration and invasion of breast cancer cells

(2012) J Zhao et al.   ONCOGENE

Psoralidin, a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation

(2011) Hee Jung Yang et al.   BIOCHEMICAL PHARMACOLOGY

The involvement of FoxO in cell survival and chemosensitivity mediated by Mirk/Dyrk1B in ovarian cancer

(2011) Jingchun Gao   INTERNATIONAL JOURNAL OF ONCOLOGY

Mitochondria in cancer: at the crossroads of life and death

(2011) Vanessa C. Fogg et al.   Chinese Journal of Cancer

DYRK1A and DYRK3 Promote Cell Survival through Phosphorylation and Activation of SIRT1

(2010) Xiumei Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting multiple kinases in glioblastoma multiforme

(2009) Sith Sathornsumetee et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS