标题
Therapeutic potential of targeting mitochondrial dynamics in cancer
作者
关键词
Bioenergetics, Cancer, Cell death, Chemotherapy, Mitochondrial dynamics
出版物
BIOCHEMICAL PHARMACOLOGY
Volume 182, Issue -, Pages 114282
出版商
Elsevier BV
发表日期
2020-10-12
DOI
10.1016/j.bcp.2020.114282
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth
- (2020) Meng Li et al. Cells
- Mitochondrial division inhibitor (mdivi-1) decreases oxidative metabolism in cancer
- (2020) Wenting Dai et al. BRITISH JOURNAL OF CANCER
- PRCC‐TFE3 regulates migration and invasion of translocation renal cell carcinomas via activation of Drp1‐dependent mitochondrial fission
- (2020) Bo Wang et al. CELL BIOLOGY INTERNATIONAL
- Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1
- (2020) Stéphanie Herkenne et al. Cell Metabolism
- The role of Drp1 in mitophagy and cell death in the heart
- (2020) Mingming Tong et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Altered Mitochondrial Dynamics in Motor Neuron Disease: An Emerging Perspective
- (2020) Manohar Kodavati et al. Cells
- Targeting mitochondria in melanoma: Interplay between MAPK signaling pathway and mitochondrial dynamics
- (2020) Letícia Silva Ferraz et al. BIOCHEMICAL PHARMACOLOGY
- A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats
- (2019) Julio C. B. Ferreira et al. Nature Communications
- Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
- (2019) Evandro F. Fang et al. NATURE NEUROSCIENCE
- Mitochondrial fission causes cisplatin resistance under hypoxic conditions via ROS in ovarian cancer cells
- (2019) Youngjin Han et al. ONCOGENE
- Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
- (2019) Sarbajeet Nagdas et al. Cell Reports
- Human Ovarian Cancer Tissue Exhibits Increase of Mitochondrial Biogenesis and Cristae Remodeling
- (2019) Anna Signorile et al. Cancers
- Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancer
- (2019) Yu Geon Lee et al. CANCER LETTERS
- Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors
- (2018) Grace R. Anderson et al. Nature Communications
- Mitochondrial Division Inhibitor 1 (mdivi-1) Protects Neurons against Excitotoxicity through the Modulation of Mitochondrial Function and Intracellular Ca2+ Signaling
- (2018) Asier Ruiz et al. Frontiers in Molecular Neuroscience
- Mechanisms Orchestrating Mitochondrial Dynamics for Energy Homeostasis
- (2018) Seungyoon B. Yu et al. JOURNAL OF MOLECULAR BIOLOGY
- Mitochondrial division inhibitor-1 potentiates cisplatin-induced apoptosis via the mitochondrial death pathway in cholangiocarcinoma cells
- (2018) Ornanong Tusskorn et al. BIOMEDICINE & PHARMACOTHERAPY
- Mitochondrial Fission Increases Apoptosis and Decreases Autophagy in Renal Proximal Tubular Epithelial Cells Treated with High Glucose
- (2016) Wen-Chin Lee et al. DNA AND CELL BIOLOGY
- Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling
- (2016) Martin D. Brand FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondria and Cancer
- (2016) Wei-Xing Zong et al. MOLECULAR CELL
- Mitochondrial Dynamics and Metabolic Regulation
- (2016) Timothy Wai et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Crosstalk between the mitochondrial fission protein, Drp1, and the cell cycle is identified across various cancer types and can impact survival of epithelial ovarian cancer patients
- (2016) Deepak Kumar Tanwar et al. Oncotarget
- Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission
- (2015) Natalia Stepanyants et al. MOLECULAR BIOLOGY OF THE CELL
- Mitochondrial Division Is Requisite to RAS-Induced Transformation and Targeted by Oncogenic MAPK Pathway Inhibitors
- (2015) Madhavika N. Serasinghe et al. MOLECULAR CELL
- Erk2 Phosphorylation of Drp1 Promotes Mitochondrial Fission and MAPK-Driven Tumor Growth
- (2015) Jennifer A. Kashatus et al. MOLECULAR CELL
- Mitochondrial control by DRP1 in brain tumor initiating cells
- (2015) Qi Xie et al. NATURE NEUROSCIENCE
- Mitochondrial Dynamics Protein Drp1 Is Overexpressed in Oncocytic Thyroid Tumors and Regulates Cancer Cell Migration
- (2015) André Ferreira-da-Silva et al. PLoS One
- p53 Is Required for Cisplatin-induced Processing of the Mitochondrial Fusion Protein L-Opa1 That Is Mediated by the Mitochondrial Metallopeptidase Oma1 in Gynecologic Cancers
- (2014) Bao Kong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Thei-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
- (2014) Ruchika Anand et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial dynamics and inheritance during cell division, development and disease
- (2014) Prashant Mishra et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Involvement of Drp1 in hypoxia-induced migration of human glioblastoma U251 cells
- (2014) YU-YING WAN et al. ONCOLOGY REPORTS
- Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency
- (2013) Sara Cogliati et al. CELL
- Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance
- (2013) Marc Schneeberger et al. CELL
- Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
- (2013) Marc Liesa et al. Cell Metabolism
- Mitochondrial Regulation of Cell Death
- (2013) S. W. G. Tait et al. Cold Spring Harbor Perspectives in Biology
- Mechanisms of Mitochondrial Fission and Fusion
- (2013) A. M. van der Bliek et al. Cold Spring Harbor Perspectives in Biology
- Depletion of mitochondrial fission factor DRP1 causes increased apoptosis in human colon cancer cells
- (2012) Akane Inoue-Yamauchi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer
- (2012) Jalees Rehman et al. FASEB JOURNAL
- BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery
- (2012) J Hagenbuchner et al. ONCOGENE
- Mitochondrial dynamics regulates migration and invasion of breast cancer cells
- (2012) J Zhao et al. ONCOGENE
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis
- (2010) Craig Brooks et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization
- (2010) Sylvie Montessuit et al. CELL
- Bcl-2 family interaction with the mitochondrial morphogenesis machinery
- (2010) M M Cleland et al. CELL DEATH AND DIFFERENTIATION
- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
- (2010) Matthew E. Gegg et al. HUMAN MOLECULAR GENETICS
- Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells
- (2010) Hidenori Otera et al. JOURNAL OF CELL BIOLOGY
- Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
- (2010) Keith T. Flaherty et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mitophagy
- (2009) Aviva M. Tolkovsky BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mitochondria and reactive oxygen species
- (2009) Alicia J. Kowaltowski et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitofusin-2 regulates mitochondrial and endoplasmic reticulum morphology and tethering: The role of Ras
- (2009) Olga Martins de Brito et al. MITOCHONDRION
- Targeting the phosphoinositide 3-kinase pathway in cancer
- (2009) Pixu Liu et al. NATURE REVIEWS DRUG DISCOVERY
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential
- (2008) Olwenn Guillery et al. BIOLOGY OF THE CELL
- Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
- (2008) Ann Cassidy-Stone et al. DEVELOPMENTAL CELL
- Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
- (2008) Gilad Twig et al. EMBO JOURNAL
- Bax- or Bak-Induced Mitochondrial Fission Can Be Uncoupled from Cytochrome c Release
- (2008) Clare Sheridan et al. MOLECULAR CELL
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