Why blood group A individuals are at risk whereas blood group O individuals are protected from SARS-CoV-2 (COVID-19) infection: A hypothesis regarding how the virus invades the human body via ABO(H) blood group-determining carbohydrates

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

The proximal origin of SARS-CoV-2

(2020) Kristian G. Andersen et al.   NATURE MEDICINE

The inorganic polymer, polyphosphate, blocks binding of SARS-CoV-2 spike protein to ACE2 receptor at physiological concentrations

(2020) Meik Neufurth et al.   BIOCHEMICAL PHARMACOLOGY

Exploitation of glycosylation in enveloped virus pathobiology

(2019) Yasunori Watanabe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Serine-rich repeat proteins from gut microbes

(2019) Dimitrios Latousakis et al.   Gut Microbes

Position of human blood group O(H) and phenotype-determining enzymes in growth and infectious disease

(2018) Peter Arend   Annals of the New York Academy of Sciences

ABO phenotype-protected reproduction based on human specific α1, 2 L-fucosylation as explained by the Bombay type formation

(2018) Peter Arend   IMMUNOBIOLOGY

The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review)

(2017) Fatima Ardito et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Plasmodium DNA-mediated TLR9 activation of T-bet+ B cells contributes to autoimmune anaemia during malaria

(2017) J. Rivera-Correa et al.   Nature Communications

Pandemics, pathogenicity and changing molecular epidemiology of cholera in the era of global warming

(2017) Fazle Rabbi Chowdhury et al.   Annals of Clinical Microbiology and Antimicrobials

Early ovariectomy reveals the germline encoding of natural anti-A- and Tn-cross-reactive immunoglobulin M (IgM) arising from developmental O -GalNAc glycosylations. (Germline-encoded natural anti-A/Tn cross-reactive IgM)

(2017) Peter Arend   Cancer Medicine

In-silico prediction and modeling of the Entamoeba histolytica proteins: Serine-rich Entamoeba histolytica protein and 29 kDa Cysteine-rich protease

(2017) Kumar Manochitra et al.   PeerJ

ABO (histo) blood group phenotype development and human reproduction as they relate to ancestral IgM formation: A hypothesis

(2016) Peter Arend   IMMUNOBIOLOGY

Epithelial cells are a source of natural IgM that contribute to innate immune responses

(2016) Wenwei Shao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Regulation of Inherently Autoreactive VH4-34–Expressing B Cells in Individuals Living in a Malaria-Endemic Area of West Africa

(2016) Geoffrey T. Hart et al.   JOURNAL OF IMMUNOLOGY

Emerging Functions of Natural IgM and Its Fc Receptor FCMR in Immune Homeostasis

(2016) Hongsheng Wang et al.   Frontiers in Immunology

The O-Linked Glycome and Blood Group Antigens ABO on Mucin-Type Glycoproteins in Mucinous and Serous Epithelial Ovarian Tumors

(2015) Varvara Vitiazeva et al.   PLoS One

α2-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes

(2015) Liz Stevenson et al.   PLoS Pathogens

Influence of ABO genotype and phenotype on angiotensin-converting enzyme plasma activity

(2014) Patricia Gassó et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Quantitative Variation in Plasma Angiotensin-I Converting Enzyme Activity Shows Allelic Heterogeneity in theABOBlood Group Locus

(2013) Chikashi Terao et al.   ANNALS OF HUMAN GENETICS

Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation

(2013) Daniela Meyer et al.   BIOCHEMICAL JOURNAL

Human Germline Antibody Gene Segments Encode Polyspecific Antibodies

(2013) Jordan R. Willis et al.   PLoS Computational Biology

Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen

(2012) Liya Hu et al.   NATURE

Spontaneous Production of Immunoglobulin M in Human Epithelial Cancer Cells

(2012) Fanlei Hu et al.   PLoS One

MicroRNA regulation of innate immune responses in epithelial cells

(2011) Rui Zhou et al.   Cellular & Molecular Immunology

Control of mucin-type O-glycosylation: A classification of the polypeptide GalNAc-transferase gene family

(2011) E. P. Bennett et al.   GLYCOBIOLOGY

A Virus-Binding Hot Spot on Human Angiotensin-Converting Enzyme 2 Is Critical for Binding of Two Different Coronaviruses

(2011) K. Wu et al.   JOURNAL OF VIROLOGY

Evidence for several waves of global transmission in the seventh cholera pandemic

(2011) Ankur Mutreja et al.   NATURE

Clues to Evolution of the SERA Multigene Family in 18 Plasmodium Species

(2011) Nobuko Arisue et al.   PLoS One

Efficient Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by the Transmembrane Protease TMPRSS2

(2010) S. Matsuyama et al.   JOURNAL OF VIROLOGY

SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway

(2008) Hongliang Wang et al.   CELL RESEARCH

Inhibition of the interaction between the SARS-CoV Spike protein and its cellular receptor by anti-histo-blood group antibodies

(2008) Patrice Guillon et al.   GLYCOBIOLOGY