Artemisinin protects endothelial function and vasodilation from oxidative damage via activation of PI3K/Akt/eNOS pathway

Matrine attenuates high‐fat diet‐induced in vivo and ox‐LDL‐induced in vitro vascular injury by regulating the PKCα/eNOS and PI3K/Akt/eNOS pathways

(2019) Song Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inflammation, Immunity, and Oxidative Stress in Hypertension—Partners in Crime?

(2019) Ian R. Barrows et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Induction of endothelial dysfunction by oxidized low-density lipoproteins via downregulation of Erk-5/Mef2c/KLF2 signaling: Amelioration by fisetin

(2019) Rohit Patel et al.   BIOCHIMIE

Baicalin alleviates atherosclerosis by relieving oxidative stress and inflammatory responses via inactivating the NF-κB and p38 MAPK signaling pathways

(2018) Yuliang Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice

(2018) Dachuan Shen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Artemisinin Prevents Glutamate-Induced Neuronal Cell Death Via Akt Pathway Activation

(2018) Shao-Peng Lin et al.   Frontiers in Cellular Neuroscience

The oxidized phospholipid POVPC impairs endothelial function and vasodilation via uncoupling endothelial nitric oxide synthase

(2017) Feng-Xia Yan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Klotho ameliorates oxidized low density lipoprotein (ox-LDL)-induced oxidative stress via regulating LOX-1 and PI3K/Akt/eNOS pathways

(2017) Yansheng Yao et al.   Lipids in Health and Disease

Tim-3 inhibits low-density lipoprotein-induced atherogenic responses in human umbilical vein endothelial cells

(2017) Ming-Ke Qiu et al.   Oncotarget

25-Hydroxycholesterol impairs endothelial function and vasodilation by uncoupling and inhibiting endothelial nitric oxide synthase

(2016) Zhi-Jun Ou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Artemisinin inhibits monocyte adhesion to HUVECs through the NF-κB and MAPK pathways in vitro

(2016) YUE WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Artemisinin protects human retinal pigment epithelial cells from hydrogen peroxide-induced oxidative damage through activation of ERK/CREB signaling

(2016) Cheong-Meng Chong et al.   Redox Biology

Phosphocreatine protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway

(2015) Anil Ahsan et al.   APOPTOSIS

Baicalin attenuates angiotensin II-induced endothelial dysfunction

(2015) Xiling Wei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Artemisinin inhibits the proliferation, migration, and inflammatory reaction induced by tumor necrosis factor-α in vascular smooth muscle cells through nuclear factor kappa B pathway

(2015) Qian Cao et al.   JOURNAL OF SURGICAL RESEARCH

Circulating microparticles from patients with valvular heart disease and cardiac surgery inhibit endothelium-dependent vasodilation

(2015) Li Fu et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Dihydromyricetin protects endothelial cells from hydrogen peroxide-induced oxidative stress damage by regulating mitochondrial pathways

(2015) Xiaolong Hou et al.   LIFE SCIENCES

LOX-1, oxidant stress, mtDNA damage, autophagy, and immune response in atherosclerosis

(2014) Zufeng Ding et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

High density lipoprotein from patients with valvular heart disease uncouples endothelial nitric oxide synthase

(2014) Feng-Jun Chang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The effects of artemisinin on the proliferation and apoptosis of vascular smooth muscle cells of rats

(2013) Hai-yang Wang et al.   CELL BIOCHEMISTRY AND FUNCTION

Endothelial Dysfunction in Morbid Obesity

(2013) Maria Mauricio et al.   CURRENT PHARMACEUTICAL DESIGN

Rapid, Direct Effects of Statin Treatment on Arterial Redox State and Nitric Oxide Bioavailability in Human Atherosclerosis via Tetrahydrobiopterin-Mediated Endothelial Nitric Oxide Synthase Coupling

(2011) Charalambos Antoniades et al.   CIRCULATION

Induction of Vascular GTP-Cyclohydrolase I and Endogenous Tetrahydrobiopterin Synthesis Protect Against Inflammation-Induced Endothelial Dysfunction in Human Atherosclerosis

(2011) Charalambos Antoniades et al.   CIRCULATION

Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease

(2011) Christian Besler et al.   JOURNAL OF CLINICAL INVESTIGATION

Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

(2011) Chang Cheng et al.   PLoS One

Atrial myocardial nox2 containing NADPH oxidase activity contribution to oxidative stress in mitral regurgitation: potential mechanism for atrial remodeling

(2010) Jen-Ping Chang et al.   CARDIOVASCULAR PATHOLOGY

Artemisinin inhibits extracellular matrix metalloproteinase inducer (EMMPRIN) and matrix metalloproteinase-9 expression via a protein kinase Cδ/p38/extracellular signal-regulated kinase pathway in phorbol myristate acetate-induced THP-1 macrophages

(2010) Yue Wang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

The anti-malarial artemisinin inhibits pro-inflammatory cytokines via the NF-κB canonical signaling pathway in PMA-induced THP-1 monocytes

(2010) Wang   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Heme oxygenase-1 expression in the left atrial myocardium of patients with chronic atrial fibrillation related to mitral valve disease: its regional relationship with structural remodeling

(2008) Domenico Corradi et al.   HUMAN PATHOLOGY